Search results for "IPA"
showing 10 items of 5795 documents
A hemocyanin from the Onychophora and the emergence of respiratory proteins
2002
The velvet worms (Onychophora) are considered living fossils and are closely related to the Euarthropoda. Onychophora possess a tracheal system for respiratory function, but oxygen-transport proteins have been considered unnecessary. Here, we show that the hemolymph of the Epiperipatus sp. (Onychophora: Peripatidae) contains an arthropod-type hemocyanin, demonstrating that such protein exists outside the Euarthropoda. Thus, the evolution of oxygen carriers preceded the divergence of the Onychophora and Euarthropoda and was most likely linked to the evolution of an efficient circulatory system in a low-oxygen environment. The cDNA of the Epiperipatus hemocyanin subunit comprises 2,287 bp an…
Expression profiling of uniparental mouse embryos is inefficient in identifying novel imprinted genes
2006
AbstractImprinted genes are expressed from only one allele in a parent-of-origin-specific manner. We here describe a systematic approach to identify novel imprinted genes using quantification of allele-specific expression by Pyrosequencing, a highly accurate method to detect allele-specific expression differences. Sixty-eight candidate imprinted transcripts mapping to known imprinted chromosomal regions were selected from a recent expression profiling study of uniparental mouse embryos and analyzed. Three novel imprinted transcripts encoding putative non-protein-coding RNAs were identified on the basis of parent-of-origin-specific monoallelic expression in E11.5 (C57BL/6 × Cast/Ei)F1 and in…
The Effects of Downturns on Labour Force Participation
2011
This paper uses an impulse-response function approach to assess the magnitude and persistence of the effects of downturns on labour force participation for a sample of 30 countries over the period 1960-2008. Past severe recessions appear to have had a significant and persistent impact on participation, while moderate downturns did not. The aggregate participation rate effect of severe downturns peaked on average at about 1½ to 2½ percentage points five to eight years after the cyclical peak, and was still significant after almost a decade. Youths and older workers account for the bulk of this effect. Institutional and policy settings are found to be an important factor having shaped the res…
Las vías de acceso al poder local en la Valencia del siglo XVIII. Continuidad y cambio de un proceso de ennoblecimiento de los oficios municipales
1987
La abolición de los fueros en 1707 y el establecimiento de la Nueva Planta como marco jurídico a partir del cual se iba a dotar de contenido a las instituciones valencianas, introdujeron cambios cualitativos en lo que venía siendo el devenir histórico del poder local. Supuso, al mismo tiempo, la concreción de una nueva dinámica en las relaciones de la Monarquía con las distintas instancias o niveles de poder existentes. Uno de ellos era el municipio y, especialmente, el municipio foral. Del conjunto de transformaciones de que fue objeto este último, quisiéramos referirnos aquí a los mecanismos de cooptación del personal político a escala local, a través de un análisis no ya de la nueva olig…
Nuevos datos biográficos sobre Juan de Miralles
1997
Aportación de nuevos datos biográficos inéditos de Juan Miralles Trayllon, negociante establecido en La Habana en 1740, elemento importante en el tráfico esclavista y agente de España durante los años de la guerra de Emancipación de los EE. UU. de América. Contribution of new unpublished biographical data of Juan Miralles Trayllon, a dealer who was established in La Havana in 1740, important element in the slaveholding traffic and agent of Spain during the years of the Emancipation war of the United States of America.
El Síndico de la ciudad de Valencia. De las Germanías a la insaculación
2001
El síndico de la ciudad de Valencia era uno de los principales cargos en el organigrama político municipal de la capital del Reino durante el periodo foral; de ahí que el sistema de provisión del mismo llegara a cobrar suficiente entidad como para suscitar deseos de control por parte de la ciudad y de la Corona. Además de analizar las características del oficio y la relación de quienes lo desempeñaron, el presente trabajo se centra en las disputas que ambos sectores de la administración mantuvieron sobre su designación, especialmente a partir del momento, a finales del Quinientos, en que se desdobla el cargo y deja de ser perpetuo, escapando al control tradicional que había venido mantenien…
Darcy–Forchheimer Magnetized Nanofluid flow along with Heating and Dissipation Effects over a Shrinking Exponential Sheet with Stability Analysis
2022
Nanoparticles have presented various hurdles to the scientific community during the past decade. The nanoparticles dispersed in diverse base fluids can alter the properties of fluid flow and heat transmission. In the current examination, a mathematical model for the 2D magnetohydrodynamic (MHD) Darcy–Forchheimer nanofluid flow across an exponentially contracting sheet is presented. In this mathematical model, the effects of viscous dissipation, joule heating, first-order velocity, and thermal slip conditions are also examined. Using similarity transformations, a system of partial differential equations (PDEs) is converted into a set of ordinary differential equations (ODEs). The problem is …
Synthetic environmental appraisal of waste management system: an application to the Sicilian region
2004
This paper addresses the problem of synthetically evaluating the environmental performances of urban solid waste systems. This, in fact, represents a crucial point in the management process of complex systems that local administrations are called to cope with, in order to provide decisions about policy options that involve different issues characterising the quality of life of people. Suitable methods of evaluation are clearly required for this aim. This work introduces the dashboard of sustainability and the ecological footprint approaches as aggregate indicators of the performances of solid waste management systems. The methods have been selected due to their intrinsic simplicities, provi…
Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analy…
2019
Background Maternal obesity and excessive gestational weight gain may have persistent effects on offspring fat development. However, it remains unclear whether these effects differ by severity of obesity, and whether these effects are restricted to the extremes of maternal body mass index (BMI) and gestational weight gain. We aimed to assess the separate and combined associations of maternal BMI and gestational weight gain with the risk of overweight/obesity throughout childhood, and their population impact. Methods and findings We conducted an individual participant data meta-analysis of data from 162,129 mothers and their children from 37 pregnancy and birth cohort studies from Europe, No…
The think aloud method in studying the translation process
2019
This paper presents a theoretical description of the process-oriented research method in translation studies known as the think aloud method and a case study of an experimental application of think-aloud protocols (TAP). The article begins with a brief description of the relevance of its topic, taking into account the state of current researches in the field of translation studies. A literature review of recent publications where the think aloud method and think-aloud protocols as the principal introspective and retrospective method in different translation studies is given. The shortcomings and advantages of applying the think aloud method are discussed and the ways to optimise the use of …