Search results for "IPM"

showing 10 items of 1361 documents

Characterization of Locally Excited and Charge-Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

2020

[EN] Lapatinib (LAP) is an anticancer drug, which is metabolized to theN- and O-dealkylated products (N-LAP andO-LAP, respectively). In view of the photosensitizing potential of related drugs, a complete experimental and theoretical study has been performed on LAP,N-LAP andO-LAP, both in solution and upon complexation with human serum albumin (HSA). In organic solvents, coplanar locally excited (LE) emissive states are generated; they rapidly evolve towards twisted intramolecular charge-transfer (ICT) states. By contrast, within HSA only LE states are detected. Accordingly, femtosecond transient absorption reveals a very fast switching (ca. 2 ps) from LE (lambda(max)=550 nm) to ICT states (…

Femtosecond transient absorptionAntineoplastic AgentsSerum Albumin HumanMolecular Dynamics Simulation010402 general chemistryLapatinib01 natural sciencesAnticancer drugsCatalysisFluorescenceQUIMICA ORGANICAComputational chemistrymedicineHumansSpectroscopy010405 organic chemistryChemistryMolecular dynamics simulationsSpectrum AnalysisOrganic Chemistrydigestive oral and skin physiologyCharge (physics)LapatinibGeneral Chemistryequipment and suppliesAnticancer drug0104 chemical sciencesCharacterization (materials science)Excited stateUltrashort pulsehuman activitiesmedicine.drug
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Thermoosmotic transfer of sterically stabilized ferrofluid particles in non-isothermal capillary porous layer

2005

Experiments on thermodiffusive transfer of ferrofluid nanoparticles in capillary porous layer are presented. The layer consists of a number of capillary filter sheets pressed between two plates of different temperatures. Steady profiles of particle concentration are detected after the experiment from magnetization of each filter sheet. It is shown that particle separation in porous layer is remarkably influenced by thermoosmotic forces. The observed effect is different for colloids of various surfactants and of various carrier liquids.

FerrofluidMaterials scienceChemical engineeringCapillary actionParticleNanoparticleequipment and suppliesCondensed Matter PhysicsPorous mediumThermal diffusivityLayer (electronics)Isothermal processElectronic Optical and Magnetic MaterialsJournal of Magnetism and Magnetic Materials
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High field magnetization of the colloidal Mn–Zn ferrite

1999

Abstract The magnetic properties of a hydrocarbon based colloid (stabilized by oleic acid) of polydisperse chemically co-precipitated Mn 0.5 Zn 0.5 Fe 2 O 4 particles are discussed in the paper. Two fractions are separated from an initial ferrofluid sample by centrifugation. X-ray diffraction measurements show the crystal structure of the particles and a broadened shape of the diffraction lines. Mean particle diameters 6.2 nm (the light fraction) and 9.7 nm (the heavy one) were determined by TEM measurements. The magnetization of the colloids is measured by VSM up to 12 T. A significant slope in the magnetization curves in the high field region is displayed for both samples in the temperatu…

FerrofluidMaterials scienceCondensed matter physicsMagnetic momentequipment and suppliesCondensed Matter PhysicsElectronic Optical and Magnetic MaterialsMagnetizationX-ray crystallographyFerrite (magnet)Magnetic nanoparticlesParticle sizehuman activitiesSpontaneous magnetizationJournal of Magnetism and Magnetic Materials
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Radiation leakage study for the Valencia applicators

2011

Abstract Introduction and purpose The Valencia applicators which are accessories of the microSelectron-HDR afterloader (Nucletron, Veenendaal, The Netherlands) are designed to treat skin lesions. These cup-shaped applicators are an alternative to superficial/orthovoltage x-ray treatment units. They limit the irradiation to the required area using tungsten-alloy shielding, and are equipped with a tungsten-alloy flattering filter allowing the treatment of skin tumors, the oral cavity, vaginal cuff, etc. The tungsten-alloy thickness to shield radiation is not the same in all parts of the applicators. This fact led us to question whether the leakage radiation differs depending on where it is me…

Film DosimetryMaterials sciencebusiness.industrymedicine.medical_treatmentBrachytherapyBrachytherapyBiophysicsGeneral Physics and AstronomyEquipment DesignGeneral MedicineDose distributionRadiation leakageRadiation ProtectionElectromagnetic shieldingmedicineDosimetryRadiology Nuclear Medicine and imagingRadiochromic filmRadiation protectionNuclear medicinebusinessMonte Carlo MethodLeakage (electronics)Biomedical engineering
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Creating an ethernet communication between a Simatic S7-1200 PLC and Arduino Mega for an omnidirectional mobile platform and industrial equipment

2020

Abstract The degree of automation in the industry increases more and more every year, trying to reduce more and more or even eliminate the collaboration with the human operator. The basis of all automatic industrial equipment is PLCs. This paper presents a method of extending the number of inputs and outputs of a Siemens Simatic S7-1200 PLC, using an Arduino Mega development board and an Ethernet communication. Following the realization of this communication, the number of inputs and outputs will increase considerably, being able to connect various sensors used for the construction of an omnidirectional mobile platform, but also for equipment for industry. The advantages of using this commu…

Flexibility (engineering)Industrial equipmentbusiness.industryComputer scienceArduinoEmbedded systemSimatic S5 PLCSiemensbusinessMega-Omnidirectional antennaAutomationIOP Conference Series: Materials Science and Engineering
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Material properties of various intraocular lenses in an experimental study.

2002

<i>Introduction:</i> With the recent introduction of small-incision cataract surgery, requirements for intraocular lens (IOL) flexibility, strength and hydrophilicity have rapidly evolved. The IOL surface, however, remains a critical factor influencing uveal biocompatibility. <i>Purpose:</i> To objectively quantify factors of material properties of various IOLs using contact angle measurements, differential scanning calorimetry, dynamic-mechanical measurements and scanning electron microscopy. <i>Material and Methods:</i> In our study, 17 currently available IOLs were investigated using contact angle measurements to assess hydrophilicity and biocompatibil…

Flexibility (engineering)Lenses Intraocularmedicine.medical_specialtygenetic structuresCalorimetry Differential ScanningComputer sciencemedicine.medical_treatmentSiliconesIntraocular lensGeneral MedicineEquipment DesignCataract surgeryeye diseasesSensory SystemsElasticityHydrogel Polyethylene Glycol DimethacrylateOphthalmologyIntraocular lensesAcrylatesOphthalmologymedicineMicroscopy Electron ScanningHumanssense organsOphthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
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Study of aerobic granular sludge stability in a continuous-flow membrane bioreactor.

2015

A granular continuous-flow membrane bioreactor with a novel hydrodynamic configuration was developed to evaluate the stability of aerobic granular sludge (AGS). Under continuous-flow operation (Period I), AGS rapidly lost their structural integrity resulting in loose and fluffy microbial aggregates in which filamentous bacteria were dominant. The intermittent feeding (Period II) allowed obtaining the succession of feast and famine conditions that favored the increase in AGS stability. Although no further breakage occurred, the formation of new granules was very limited, owing to the absence of the hydraulic selection pressure. These results noted the necessity to ensure, on the one hand the…

FlocculationEnvironmental EngineeringAerobic granular sludge (AGS)Segmented filamentous bacteria0208 environmental biotechnologyMicrobial ConsortiaBiomassBioengineering02 engineering and technology010501 environmental sciencesMembrane bioreactor01 natural sciencesWaste Disposal FluidBioreactorsBreakageBioreactorPressureBiomassWaste Management and Disposal0105 earth and related environmental sciencesContinuous-flow reactorSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleBacteriaSewageRenewable Energy Sustainability and the EnvironmentChemistryContinuous flowFeast/famine conditionMembraneEnvironmental engineeringWashoutFlocculationGeneral MedicineEquipment DesignPulp and paper industryAerobiosis020801 environmental engineeringHydraulic selection pressureAerobic granular sludge (AGS); Continuous-flow reactor; Feast/famine conditions; Hydraulic selection pressure; Membrane; Bioengineering; Environmental Engineering; Waste Management and DisposalBioresource technology
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Urea as a PCDD/F inhibitor in municipal waste incineration.

2001

Emissions of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) from municipal waste incineration have been widely studied because of their extensive toxicity, and many efforts have been made to restrict their emissions. Although a number of chemical compounds have been shown in laboratory-scale tests to inhibit the formation of PCDD/Fs, few have been tested in pilot- or full-scale plants. This work evaluates the effect of urea as a PCDD/F inhibitor in a pilot-scale incinerator that uses refuse-derived fuel (RDF). The decomposition of urea under the test conditions was also studied using detailed kinetic modeling. An aqueous solution of urea was injected into the flue gas stream …

Flue gasMunicipal solid wasteAqueous solutionPolychlorinated DibenzodioxinsEquipment DesignIncinerationManagement Monitoring Policy and LawIncinerationRefuse DisposalWaste treatmentchemistry.chemical_compoundKineticschemistryEnvironmental chemistryUreaSoil PollutantsUreaWaste Management and DisposalRefuse-derived fuelChemical decompositionBenzofuransJournal of the AirWaste Management Association (1995)
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Experimental research of surfaced nanoparticle thermal transport in a porous medium

2018

Abstract Experimental research on thermally induced nanocolloid transport in a porous environment is presented. Addition of excess surfactant to a colloid with dispersed phase made of surfaced nanoparticles results in a decrease of effective Soret coefficient in a porous environment. It is shown that with sufficient amounts of surfactant added, this effect extends to a reversal of nanoparticle thermophoretic transport direction, and that the effect shows a tendency of saturation. A mechanism of thermal transport that involves slip velocity of surfactant molecules appearing near pore walls is evaluated as a possible cause of the decrease of Soret coefficient. Effects of temperature on partic…

Fluid Flow and Transfer ProcessesMaterials scienceMechanical Engineeringtechnology industry and agricultureNanoparticle02 engineering and technologyequipment and supplies021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesThermophoresis010305 fluids & plasmasColloidPulmonary surfactantChemical engineering0103 physical sciencesMolecule0210 nano-technologyPorous mediumPorositySaturation (magnetic)International Journal of Heat and Mass Transfer
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Simultaneous Flow over and under a Gate

2000

This paper reports the results of an investigation carried out to establish the stage-discharge relationship for a flow simultaneously discharging over and under a sluice or a broad-crested gate. The stage-discharge relationship is deduced by a theoretical analysis, based on the application of the Π-theorem of the dimensional analysis and the incomplete self-similarity theory, coupled with an experimental investigation carried out by using a laboratory flume.

FlumeWater flowHydraulic equipmentSluiceFlow (psychology)WeirMeasuring instrumentEnvironmental scienceGeotechnical engineeringAgricultural and Biological Sciences (miscellaneous)Discharge coefficientWater Science and TechnologyCivil and Structural EngineeringJournal of Irrigation and Drainage Engineering
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