Search results for "IPT"

A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA b…

2002

The Cockayne syndrome B (CSB) gene product is involved in the repair of various types of base modifications in actively transcribed DNA sequences. To investigate its significance for the repair of endogenous oxidative DNA damage, homozygous csb(-/-)/ogg1(-/-) double knockout mice were generated. These combine the deficiency of CSB with that of OGG1, a gene coding for the mammalian repair glycosylase that initiates the base excision repair of 7,8-dihydro-8-oxoguanine (8-oxoG). Compared to ogg1(-/-) mice, csb(-/-)/ogg1(-/-) mice were found to accumulate with age severalfold higher levels of oxidited purine modifications in hepatocytes, splenocytes and kidney cells. In contrast, the basal (ste…

In Vitro Study on Bone Heating during Drilling of the Implant Site: Material, Design and Wear of the Surgical Drill

2020

Objective: An in vitro study was made to compare mean thermal variation according to the material, design and wear of the surgical drills used during dental implant site preparation. Material and methods: Three study groups (stainless steel drills with straight blades

Dissonance and Neutralization of Subscription Streaming Era Digital Music Piracy : An Initial Exploration

2016

Both legal and illegal forms of digital music consumption continue to evolve with wider adoption of subscription streaming services. With this paper, we aim to extend theory on digital music piracy by showing that the rising controversy and diminishing acceptance of illegal forms of consumption call for new theoretical components and interactions. We introduce a model that integrates insights from neutralization and cognitive dissonance theories. As an initial empirical test of the proposed Dissonance-Neutralization model, we estimate a structural equation model based on self-administered survey data obtained from 322 respondents. Our results uncover potential demographic differences in pir…

Happiness is ... a good transcription : shortcomings in the sheet music publications in the music of the Beatles (1967-68)

2001

Happiness is... a good transcription : reconsidering the Beatles sheet music publications

2006

Hankkiessaan Beatles-nuotinnoksen käsiinsä ei kuluttajalla välttämättä ole ollenkaan käsitystä siitä, minkä tasoinen kulloinenkin nuotinnos on, eli kuinka luotettava se on verrattuna alkuperäiseen lähteeseen eli levyyn. Musiikin käyttäjälle olisi varmasti paljon hyötyä ja iloa siitä, jos nuotit vastaisivat paremmin levyjä – valitettavasti vain julkaistut nuotinnokset ovat suurelta osin puutteellisia ja jättäneet paljon toivomisen varaa. Myös maailmalla erittäin paljon myydyn ja tunnetun ”The Beatles Complete Scoresin” transkriptiot ovat monelta osin kaukana siitä mitä levyillä todellisuudessa on. Nuottien kustantaminen on yhä edelleenkin suurta bisnestä, mutta sitä ei ole kuitenkaan jostain…

Utilisation et possibilités de méthodes dites -omiques en viticulture

2020

In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides

2012

Withania somnifera (L.) Dunal (Indian ginseng, winter cherry, Solanaceae) is widely used in traditional medicine. Roots are either chewed or used to prepare beverages (aqueous decocts). The major secondary metabolites of Withania somnifera are the withanolides, which are C-28-steroidal lactone triterpenoids. Withania somnifera extracts exert chemopreventive and anticancer activities in vitro and in vivo. The aims of the present in silico study were, firstly, to investigate whether tumor cells develop cross-resistance between standard anticancer drugs and withanolides and, secondly, to elucidate the molecular determinants of sensitivity and resistance of tumor cells towards withanolides. Usi…

Aging-associated changes in NF-kappa Β signaling

2000

Macroscytus raunoi, a new burrower bug species from Papua New Guinea (Hemiptera: Heteroptera: Cydnidae: Cydninae)

2016

Abstract Macroscytus raunoi, a new species of the genus Macroscytus Fieber, 1860, is described from the Morobe Province on the northern coast of Papua New Guinea. The new species is similar in its morphological characters to Australian M. arnhemicus J. A. Lis, 1999. Differences in morphology and male genitalia which enable separation of both species are provided.

Taxonomic review of the

2017

Abstract Two new species of the genus Fulvius Stål are described from the Philippines and Papua New Guinea. A taxonomic review of representatives of the F.bifenestratus species group, illustrations of the male genitalia, a color habitus image of each species, and a key to species of the group are provided.