Search results for "IQ"
showing 10 items of 21401 documents
Lièvre et lapin à Regourdou (Montignac-sur-Vézère, Dordogne, France) : études paléontologique et taphonomique de deux accumulations osseuses d’origin…
2015
Since the end of the nineteenth century, a great deal of work studyingsubsistence patterns of prehistoric societies in Western Europe has been done. During the Middle Paleolithic, humanswere interested in small game, particularly the Leporidae, taxa that were abundant in their territories. However,distinguishing the exact nature of their origin in an archaeological site is not an easy task, given that numerous agentscould be responsible for their accumulation (i.e., natural mortality, acquisition by humans and/or other terrestrialcarnivores, or even nocturnal or diurnal raptors). In this contribution, we put forth a new taphonomic and paleontologicalstudy of the leporids of Regourdou, a Mou…
Chiral Serum Pharmacokinetics of 4-Fluoroamphetamine after Controlled Oral Administration
2021
Abstract Over the last two decades, misuse of 4-fluoroamphetamine (4-FA) became an emerging issue in many European countries. Stimulating effects last for 4–6 hours and can impact psychomotor performance. The metabolism of amphetamine-type stimulants is stereoselective and quantification of (R)- and (S)-enantiomers has been suggested for assessing time of use. To date, no data on enantioselective pharmacokinetics is available for 4-FA in serum samples. An enantioselective liquid chromatography−tandem mass spectrometry (LC–MS-MS) method was developed using a chiral Phenomenex® Lux 3 μm AMP column. Validation of the method showed satisfactory selectivity, sensitivity, linearity (0.5–250 ng/mL…
Synthesis of New 2-{[(Phenoxy or Phenyl)acetyl]amino}benzoic Acid Derivatives as 3α-Hydroxysteroid Dehydrogenase Inhibitors and Potential Antiinflamm…
1995
A number of 2-([(phenoxy or phenyl)acetyl]amino)benzoic acid derivatives were prepared in about 50% yield from (phenoxy or phenyl)acetyl chloride and anthranilic acid derivatives. All the compounds were tested as in vitro inhibitors of 3 alpha-hydroxysteroid dehydrogenase, since enzyme inhibition predicts potential antiinflammatory activity in vivo. The most active compounds 3 l, m, s are about 3.5 times more active than acetylsalicylic acid (ASA). Activity is influenced by electronic as well as steric effects.
Dehn surgeries and smooth structures on 3-dimensional transitive Anosov flows.
2020
The present thesis is about Dehn surgeries and smooth structures associated with transitive Anosov flows in dimension three. Anosov flows constitute a very important class of dynamical systems, because of its persistent chaotic behaviour, as well as for its rich interaction with the topology of the ambient space. Even if a lot is known about the dynamical and ergodic properties of these systems, there is not a clear understanding about how to classify its different orbital equivalence classes. Until now, the biggest progress has been done in dimension three, where there is a family of techniques intended for the construction of Anosov flows called surgeries.During the realization of this th…
Glycerosomes: Use of hydrogenated soy phosphatidylcholine mixture and its effect on vesicle features and diclofenac skin penetration.
2016
In this work, diclofenac was encapsulated, as sodium salt, in glycerosomes containing 10, 20 or 30% of glycerol in the water phase with the aim to ameliorate its topical efficacy. Taking into account previous findings, glycerosome formulation was modified, in terms of economic suitability, using a cheap and commercially available mixture of hydrogenated soy phosphatidylcholine (P90H). P90H glycerosomes were spherical and multilamellar; photon correlation spectroscopy showed that obtained vesicles were ∼131nm, slightly larger and more polydispersed than those made with dipalmitoylphosphatidylcholine (DPPC) but, surprisingly, they were able to ameliorate the local delivery of diclofenac, whic…
Diseños de investigación de estudios observacionales analíticos.
2016
En este vídeo se explican las principales características de los estudios de investigación observacionales analíticos, en cuanto a diseño y procedimientos. En concreto se consideran los estudios de cohortes prospectivo y retrospectivo y el de casos y controles.
Estudios de investigación experimentales
2016
En este vídeo se explican las principales características de los estudios de investigación experimentales, en cuanto a diseño y procedimientos. En concreto se consideran los estudios experimentales (ensayos clínicos aleatorizados y no aleatorizados) y los estudios cuasi-experimentales (diseño de series temporales y experimentos cruzados).
FAL CODO
2018
Autor: Espí López, Gemma V; Conesa Albaladejo, María; Matoses March, Carmen; Zurano Conches, Igncio; Serra Añó, Pilar; Alberola Zorrilla, Pilar; Garriga Hinarejos, Antonio; Gozálvez Gozálvez, Anier; Navarro Orero, David; Villagrasa Sanz, Jesús; Práctica Fisioterapia del Aparato Locomotor (FAL) de Codo. Técnicas específicas de la Asignatura de Fisioterapia del Aparato Locomotor.
FAL LUMBAR-SACRO-PELVIS
2018
Autor: Espí López, Gemma V; Conesa Albaladejo, María; Matoses March, Carmen; Zurano Conches, Igncio; Serra Añó, Pilar; Alberola Zorrilla, Pilar; Garriga Hinarejos, Antonio; Gozálvez Gozálvez, Anier; Navarro Orero, David; Villagrasa Sanz, Jesús; Práctica Fisioterapia del Aparato Locomotor (FAL) de LUMBAR-SACRO-PELVIS. Técnicas específicas de la Asignatura de Fisioterapia del Aparato Locomotor.
FAL CADERA
2018
Autor: Espí López, Gemma V; Conesa Albaladejo, María; Matoses March, Carmen; Zurano Conches, Igncio; Serra Añó, Pilar; Alberola Zorrilla, Pilar; Garriga Hinarejos, Antonio; Gozálvez Gozálvez, Anier; Navarro Orero, David; Villagrasa Sanz, Jesús; Práctica Fisioterapia del Aparato Locomotor (FAL) de CADERA. Técnicas específicas de la Asignatura de Fisioterapia del Aparato Locomotor.