Search results for "IS Method"

showing 10 items of 730 documents

Comparison of Diffusion MRI Acquisition Protocols for the In Vivo Characterization of the Mouse Spinal Cord: Variability Analysis and Application to …

2016

Diffusion-weighted Magnetic Resonance Imaging (dMRI) has relevant applications in the microstructural characterization of the spinal cord, especially in neurodegenerative diseases. Animal models have a pivotal role in the study of such diseases; however, in vivo spinal dMRI of small animals entails additional challenges that require a systematical investigation of acquisition parameters. The purpose of this study is to compare three acquisition protocols and identify the scanning parameters allowing a robust estimation of the main diffusion quantities and a good sensitivity to neurodegeneration in the mouse spinal cord. For all the protocols, the signal-to-noise and contrast-to noise ratios…

MaleDTI-MRI spinal cord ALSPathologylcsh:MedicineSignal-To-Noise RatioNervous System030218 nuclear medicine & medical imagingDiagnostic RadiologyDiffusionMice0302 clinical medicineSuperoxide Dismutase-1Materials PhysicsMedicine and Health SciencesImage Processing Computer-AssistedAmyotrophic lateral sclerosisDiffusion (business)lcsh:ScienceMicrostructureMusculoskeletal SystemBrain MappingMultidisciplinarymedicine.diagnostic_testRadiology and ImagingPhysicsAnimal ModelsCondensed Matter PhysicsMagnetic Resonance Imagingmedicine.anatomical_structureDiffusion Tensor ImagingSpinal CordPhysical SciencesAnatomyResearch Articlemedicine.medical_specialtyImaging TechniquesBrain MorphometryMaterials ScienceMaterial PropertiesNeuroimagingMouse ModelsMice TransgenicResearch and Analysis Methods03 medical and health sciencesModel OrganismsDiagnostic MedicineFractional anisotropymedicineAnimalsSensitivity (control systems)AllelesProtocol (science)business.industryAmyotrophic Lateral Sclerosislcsh:RBiology and Life SciencesReproducibility of ResultsMagnetic resonance imagingmedicine.diseaseSpinal cordSpineNeuroanatomyDisease Models AnimalDiffusion Magnetic Resonance ImagingMutationAnisotropylcsh:Qbusiness030217 neurology & neurosurgeryBiomedical engineeringDiffusion MRINeurosciencePLoS ONE
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Longitudinal changes in physical activity, sedentary behavior and body mass index in adolescence: Migrations towards different weight cluster

2016

This study examined longitudinal changes in physical activity, sedentary behavior and body mass index in adolescents, specifically their migrations towards a different weight cluster. A cohort of 755 adolescents participated in a three-year study. A clustering Self-Organized Maps Analysis was performed to visualize changes in subjects' characteristics between the first and second assessment, and how adolescents were grouped. Also a classification tree was used to identify the behavioral characteristics of the groups that changed their weight cluster. Results indicated that boys were more active and less sedentary than girls. Boys were especially keen to technological-based activities while …

MaleDecision AnalysisPhysiologyHealth Behaviorlcsh:MedicineOverweightAdolescentsBody Mass Index0302 clinical medicineAnimal CellsMedicine and Health SciencesPublic and Occupational HealthLongitudinal Studies030212 general & internal medicineYoung adultlcsh:ScienceChildNeuronsMultidisciplinarySedentary behaviorPhysiological ParametersResearch DesignCohortEngineering and TechnologyFemaleCellular Typesmedicine.symptomPsychologyManagement EngineeringResearch ArticleAdultmedicine.medical_specialtyAdolescentMotor ActivityResearch and Analysis MethodsDisease clusterYoung Adult03 medical and health sciencesThinnessmedicineHumansObesityExercise physiologyExerciseBehaviorlcsh:RBody WeightDecision TreesBiology and Life SciencesCell BiologyPhysical Activity030229 sport sciencesOverweightmedicine.diseaseObesitySpainAge GroupsCellular NeurosciencePeople and PlacesPhysical therapylcsh:QPopulation GroupingsSedentary BehaviorBody mass indexNeuroscienceDemographyPLOS ONE
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The biometric antecedents to happiness

2017

It has been suggested that biological markers are associated with human happiness. We contribute to the empirical literature by examining the independent association between various aspects of biometric wellbeing measured in childhood and happiness in adulthood. Using Young Finns Study data (n = 1905) and nationally representative linked data we examine whether eight biomarkers measured in childhood (1980) are associated with happiness in adulthood (2001). Using linked data we account for a very rich set of confounders including age, sex, body size, family background, nutritional intake, physical activity, income, education and labour market experiences. We find that there is a negative rel…

MaleEmotionsHappinessSocial Scienceslcsh:MedicineBlood Pressure050109 social psychologyBiochemistryVascular MedicineDevelopmental psychologyPregnancyMedicine and Health ScienceshappinessPsychologyEthnicitiesPublic and Occupational Health050207 economicsChildlcsh:Scienceta512Finlandmedia_commonMultidisciplinary05 social sciencesConfoundingAge FactorsBiometricsAdipose TissueChild PreschoolFemaleAnatomyPsychologyResearch ArticleAdultAdolescentBiometrics515 Psychologymedia_common.quotation_subjectPhysical activityResearch and Analysis MethodsSex FactorsComputational Techniques0502 economics and businessAdultsHumansPersonality0501 psychology and cognitive sciencesAssociation (psychology)Triglyceridesbiometric antecedentslcsh:RBiology and Life SciencesPhysical Activityta3121ta3123Biological TissueAge GroupsNegative relationshipPeople and PlacesHappinessPopulation Groupingslcsh:QLiterature studyBiomarkersFinnsFollow-Up StudiesPLOS ONE
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Qualitative analysis of the Best Possible Self intervention: Underlying mechanisms that influence its efficacy.

2019

BackgroundThe Best Possible Self is a Positive Psychology Intervention which asks participants to write down about themselves in their best possible future. Previous studies have shown its efficacy to enhance wellbeing, but the mechanisms that underlie its efficacy are still unknown.ObjectiveThe aim of this study was to analyze the content of the essays of the BPS intervention and to examine how this content was related to the efficacy of the intervention to increase positive affect.MethodParticipants (N = 78) were randomized to either the Best Possible Self condition, or one of two variants of the intervention: one's best self in the present, and one's best self in the past. Qualitative an…

MaleEmotionsPsychological interventionSocial Sciences050109 social psychologyDevelopmental psychologyMathematical and Statistical TechniquesLearning and MemorySociologyMedicine and Health SciencesPsychologyHuman Familiesmedia_commonMultidisciplinaryStatistics05 social sciencesQRMetaanalysisSelf EfficacyPsychology PositivePhysical SciencesRegression AnalysisMedicineFemalePositive psychologyPsychologyResearch ArticleAdultMediation (statistics)Adolescentmedia_common.quotation_subjectScienceQualitative propertyResearch and Analysis MethodsInterpersonal Relationships050105 experimental psychologyHuman LearningInterpersonal relationshipIntervention (counseling)Mental Health and PsychiatryHumansLearning0501 psychology and cognitive sciencesStatistical MethodsSelf-efficacyCognitive PsychologyBiology and Life SciencesCollective Human BehaviorHappinessCognitive ScienceMathematicsNeurosciencePLoS ONE
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Regional variations in Helicobacter pylori infection, gastric atrophy and gastric cancer risk: The ENIGMA study in Chile.

2020

International audience; Background: Regional variations in gastric cancer incidence are not explained by prevalence of Helicobacter pylori, the main cause of the disease, with several areas presenting high H. pylori prevalence but low gastric cancer incidence. The IARC worldwide H. pylori prevalence surveys (ENIGMA) aim at systematically describing age and sex-specific prevalence of H. pylori infection around the world and generating hypotheses to explain regional variations in gastric cancer risk.Methods: We selected age- and sex-stratified population samples in two areas with different gastric cancer incidence and mortality in Chile: Antofagasta (lower rate) and Valdivia (higher rate). Pa…

MaleEpidemiologyPathology and Laboratory MedicineGastroenterologyGeographical locations0302 clinical medicineRisk FactorsHelicobacterEpidemiology of cancerPrevalenceMedicine and Health SciencesMedicineChileEnzyme-Linked ImmunoassaysYoung adultChildeducation.field_of_studyMultidisciplinary[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologybiologyCancer Risk FactorsStomachQRMiddle AgedBacterial Pathogens3. Good healthOncologyMedical MicrobiologyChild Preschool030220 oncology & carcinogenesisMedicineFemale030211 gastroenterology & hepatologyPathogensCancer EpidemiologyResearch ArticleAdultmedicine.medical_specialtyAdolescentSciencePopulationResearch and Analysis MethodsMicrobiologyHelicobacter InfectionsYoung Adult03 medical and health sciencesSigns and SymptomsAtrophyStomach NeoplasmsInternal medicineGastrointestinal TumorsHumansCagASeroprevalenceImmunoassayseducationMicrobial PathogensAgedChile (Country)Bacteriabusiness.industryOrganismsInfantBiology and Life SciencesCancers and NeoplasmsCancerSouth AmericaHelicobacter pylorimedicine.diseasebiology.organism_classificationHelicobacter Pyloridigestive system diseasesGastric CancerAge GroupsMedical Risk FactorsPeople and PlacesImmunologic TechniquesPopulation GroupingsClinical MedicineAtrophybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyPLoS ONE
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Analysis of Mycobacterium tuberculosis-Specific CD8 T-Cells in Patients with Active Tuberculosis and in Individuals with Latent Infection

2009

CD8 T-cells contribute to control of Mycobacterium tuberculosis infection, but little is known about the quality of the CD8 T-cell response in subjects with latent infection and in patients with active tuberculosis disease. CD8 T-cells recognizing epitopes from 6 different proteins of Mycobacterium tuberculosis were detected by tetramer staining. Intracellular cytokines staining for specific production of IFN-gamma and IL-2 was performed, complemented by phenotyping of memory markers on antigen-specific CD8 T-cells. The ex-vivo frequencies of tetramer-specific CD8 T-cells in tuberculous patients before therapy were lower than in subjects with latent infection, but increased at four months a…

MaleEpitopes T-Lymphocytelcsh:MedicineCD8-Positive T-LymphocytesEpitopeDiagnostic RadiologyInfectious Diseases/Bacterial InfectionsSpectrum Analysis TechniquesCellular typesCytotoxic T celllcsh:ScienceImage Cytometryeducation.field_of_studyMultidisciplinarybiologyRadiology and ImagingImmune cellsInfection ImagingMiddle AgedFlow CytometryActinobacteriaPhenotypeSpectrophotometryCytokinesWhite blood cellsFemaleCytophotometryResearch Articlemedicine.drugInterleukin 2Cell biologyBlood cellsTuberculosisImaging TechniquesImmunologyPopulationT cellsCytotoxic T cellsResearch and Analysis MethodsMycobacterium tuberculosisDiagnostic MedicineImmunology/Immunity to InfectionsHLA-A2 AntigenmedicineHumansTuberculosiseducationMedicine and health sciencesHLA-A AntigensBacteriaFluorimetrylcsh:ROrganismsBiology and Life SciencesMycobacterium tuberculosisbiology.organism_classificationmedicine.diseaseVirologyRetractionAnimal cellsImmunology/Immune ResponseImmunologyMycobacterium tuberculosis CD8 T cells Tuberculosis Latent Infectionlcsh:QCD8MycobacteriumPLoS ONE
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Sexual orientation predicts men’s preferences for sexually dimorphic face-shape characteristics: A replication study

2020

Many researchers have proposed that straight men prefer women’s faces displaying feminine shape characteristics at least partly because mating with such women will produce healthier offspring. Although a prediction of thisadaptation-for-mate-choicehypothesis is that straight men will show stronger preferences for feminized versus masculinized versions of women’s faces than will gay men, only one previous study has directly tested this prediction. Here we directly replicated that study by comparing 623 gay and 3163 straight men’s preferences for feminized versus masculinized versions of faces. Consistent with the adaptation-for-mate-choice hypothesis of straight men’s femininity preferences,…

MaleEthnic groupSocial Sciences050109 social psychologyChoice Behavior5. Gender equalityPsychological AttitudesMedicine and Health SciencesEthnicitiesPsychologyHomosexualsmedia_commonSex CharacteristicsMultidisciplinaryQ05 social sciencesRResearch AssessmentFemininityResearch DesignMasculinitybehavior and behavior mechanismsMedicineEngineering and TechnologyFemaleAnatomyPsychologySocial psychologyResearch ArticleAdultSciencemedia_common.quotation_subjectSexual BehaviorReplication StudiesBFResearch and Analysis MethodsInterpersonal Relationships050105 experimental psychologyFace shapeInterpersonal relationshipPrototypesHumans0501 psychology and cognitive sciencesMasculinityBiology and Life SciencesSexual dimorphismFemininityTechnology DevelopmentCollective Human BehaviorFacePeople and PlacesSexual orientationRomantic partnersPopulation GroupingsHeadSexuality GroupingsPLoS ONE
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The effect of an extra piece of fruit or vegetables at school on weight status in two generations - 14 years follow-up of the Fruit and Vegetables Ma…

2018

Background: The obesity epidemic presents a major public health challenge, and a poor diet quality has been identified as one of the most important contributing factors. Whereas a sufficient fruit and vegetable consumption has been associated with several positive health outcomes, the long-term effect on overweight and obesity is unclear. Thus, the aims of this study were to investigate if one year with free school fruit had any effect on weight status 14 years later, and if it affected the birth weight of the participants’ children. Methods: In 2001, 10 -12-year old Norwegian children, received one year of free school fruit in the intervention study “Fruits and Vegetables Make the Marks” (…

MaleEuropean PeoplePhysiologylcsh:MedicineSocial SciencesSurveysOverweightFamilies0302 clinical medicineSociologyVegetablesPrevalenceMedicine and Health SciencesBirth WeightEthnicities030212 general & internal medicineParent-Child Relationslcsh:ScienceChildChildrenSchoolsMultidisciplinaryEukaryotaPlantsPhysiological ParametersResearch DesignlanguageFemaleDiet Healthymedicine.symptomResearch ArticleAdultmedicine.medical_specialtyNorwegian PeopleOffspringBirth weight030209 endocrinology & metabolismNorwegianResearch and Analysis MethodsEducationFruits03 medical and health sciencesSex FactorsmedicineHumansObesityEducational AttainmentSchool Health ServicesSurvey Researchbusiness.industryPublic healthlcsh:RBody WeightInfant NewbornOrganismsBiology and Life SciencesFeeding BehaviorOdds ratioOverweightmedicine.diseaseObesitylanguage.human_languageLow birth weightSocioeconomic FactorsAge GroupsFruitPeople and Placeslcsh:QPopulation GroupingsbusinessFollow-Up StudiesDemography
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Prevalence of intimate partner violence against women in Sweden and Spain: A psychometric study of the 'Nordic paradox'.

2019

The high prevalence of intimate partner violence against women (IPVAW) in countries with high levels of gender equality has been defined as the "Nordic paradox". In this study we compared physical and sexual IPVAW prevalence data in two countries exemplifying the Nordic paradox: Sweden (N = 1483) and Spain (N = 1447). Data was drawn from the European Union Agency for Fundamental Rights Survey on violence against women. To ascertain whether differences between these two countries reflect true differences in IPVAW prevalence, and to rule out the possibility of measurement bias, we conducted a set of analyses to ensure measurement equivalence, a precondition for appropriate and valid cross-cul…

MaleEuropean PeopleSpanish PeoplePhysiologyEpidemiologyEmotionsIntimate Partner ViolenceSocial Sciences050109 social psychologyCriminologySurveysGeographical locations0302 clinical medicineSociologyRisk FactorsReproductive PhysiologySurveys and QuestionnairesCopulationPrevalenceMedicine and Health SciencesEthnicitiesPublic and Occupational Health030212 general & internal medicineYoung adultHispanic Peoplemedia_commonMultidisciplinary05 social sciencesComparabilityTraumatic Injury Risk FactorsQRMiddle AgedConfirmatory factor analysisEuropeResearch DesignMedicineFemaleCrimePsychologyResearch ArticleAdultCross-Cultural ComparisonAdolescentPsychometricsScienceSample (statistics)Research and Analysis MethodsSexual and Gender Issues03 medical and health sciencesYoung AdultBiasmedia_common.cataloged_instanceHumans0501 psychology and cognitive sciencesEuropean UnionEuropean unionViolent CrimeAgedProbabilitySwedenSurvey ResearchBiology and Life SciencesSamhällsvetenskapDifferential item functioningCross-cultural studiesSpainMedical Risk FactorsDomestic violencePopulation GroupingsPeople and placesDemographyPLoS ONE
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Relationship between perception of smile esthetics and orthodontic treatment in Spanish patients

2018

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201102 One of the main objectives of orthodontic treatment is to achieve an esthetic smile. This study set out to analyze differences in the perception of smile esthetics among patients before and after receiving orthodontic treatment. 250 Spanish patients analyzed a single photograph in which, by means of computer software, midline diastema, black triangle, gingival margin of the left central incisor, and gingival (ªgummyº) smile were altered. Each patient analyzed these images before and after undergoing orthodontic treatment. Patient…

MaleEuropean PeopleVisual perceptionTeethSpanish Peoplegenetic structuresGingivaSocial Scienceslcsh:MedicineOrthodontics.SmilingOrthodontics CorrectiveAttitudes (Psychology)IncisorsBeauty0302 clinical medicineGummy smileComputer softwareMedicine and Health SciencesMedicinePsychologyEthnicities030212 general & internal medicineUpper central incisorlcsh:ScienceHispanic Peoplemedia_commonOrthodonticsMultidisciplinaryOdontología estética.Research AssessmentModels DentalReproducibilityIncisorPhotography DentalVisual PerceptionFemaleAnatomyResearch ArticleAdultComputer and Information SciencesAdolescentEstheticsmedia_common.quotation_subjectOral MedicineOrthodonticsResearch and Analysis MethodsComputer Software03 medical and health sciencesYoung AdultDientes - Estética.PerceptionOrtodoncia.HumansMaxillary central incisorComputer Simulationbusiness.industrylcsh:RDental ModelsBiology and Life Sciences030206 dentistryJawSpainAge GroupsDentistryPeople and PlacesDentistry - Aesthetic aspects.Population Groupingslcsh:Qsense organsbusinessDigestive SystemHeadSoftwareGingival margin
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