Search results for "ISOC"

showing 10 items of 301 documents

Magnetic Resonance Imaging Derived Biomarkers of IDH Mutation Status and Overall Survival in Grade III Astrocytomas

2020

The evaluation of the isocitrate dehydrogenase (IDH) mutation status in the glioma decision-making process has diagnostic, prognostic and therapeutic implications. The aim of this study was to evaluate whether conventional magnetic resonance imaging (MRI) and apparent diffusion coefficient (ADC) can noninvasively predict the most common IDH mutational status (R132H) in GIII-astrocytomas and the overall survival (OS). Hence, twenty-two patients (9-F, 13-M) with a histological diagnosis of GIII-astrocytoma and evaluation of IDH-mutation status (12-wild type, 10-mutant) were retrospectively evaluated. Imaging studies were reviewed for the morphological feature and mean ADC values (ADCm). Stati…

medicine.medical_specialtyoverall survivalClinical BiochemistryradiogenomicsRadiogenomicsGastroenterologyArticle03 medical and health sciences0302 clinical medicineGliomaInternal medicinemedicineOverall survivalEffective diffusion coefficientdiffusion weighted imaging (DWI)apparent diffusion coefficient (ADC)lcsh:R5-920medicine.diagnostic_testbusiness.industryanaplastic astrocytomaMagnetic resonance imagingmedicine.diseaseExact testIsocitrate dehydrogenaseisocitrate dehydrogenase (IDH) mutation030220 oncology & carcinogenesisHuman medicinelcsh:Medicine (General)businessanaplastic astrocytomas030217 neurology & neurosurgeryAnaplastic astrocytomaDiagnostics
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High-intensity interval training and moderate intensity training with exogenous adenosine counteract development of obesity in rats

2022

Objectives High-Intensity Interval Training (HIIT) and Moderate Intensity Training (MIT) can combat the obesity epidemic. However, studies comparing their effects on obesity show controversial findings regarding weight loss. Adenosine has emerged as a possible, novel therapeutic agent to treat obesity, but more preclinical studies on its efficacy are needed. Therefore, the objectives of this study were to compare the effects of HIIT and MIT on obesity, and further to determine the dose-dependent effects of adenosine on body weight. Equipment and methods We induced obesity in male Wistar rats with high-fat diet (HFD) and monitored development of obesity by comparing the weight to rats on nor…

obesityexercisekuntoliikuntaadenosiiniintervalliharjoitteluModerate Intensity Training (MIT)painonhallintaenergy intakelihavuusOrthopedics and Sports Medicineexogenous adenosineHigh-Intensity Interval Training (HIIT)weight losskoe-eläinmallitisocaloricHigh Fat diet (HFD)
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Asymmetric Organocatalytic Synthesis of 4-Aminoisochromanones via a Direct One-Pot Intramolecular Mannich Reaction

2016

Synthesis 48(24), 4451 - 4458(2016). doi:10.1055/s-0035-1562522

one-pot reaction010405 organic chemistryChemistryOrganic Chemistryasymmetric synthesisEnantioselective synthesis010402 general chemistry54001 natural sciencesMedicinal chemistryCatalysis0104 chemical sciencesCatalysisIntramolecular forceOne pot reactionOrganocatalysisddc:540isochromanonesMannich reactionOrganic chemistryAmine gas treatingStereoselectivityorganocatalysisMannich reactionorganocatalysis; one-pot reaction; asymmetric synthesis; isochromanones; Mannich reaction
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La formazione a Sparta e ad Atene fra tradizione e teoria filosofica: il dibattito sulla 'paideia'

2001

Attraverso una carrellata selettiva di testi filosofici e letterari, nonché attraverso un complessivo riesame delle fonti primarie e secondarie, l'articolo propone una ridiscussione, a scopo eminentemente divulgativo, dell'ideale greco della 'paideia'. Da una prospettiva primariamente storico-pedagogica si mette a fuoco la presenza, nel tessuto culturale delle 'poleis' greche (e in special modo a Sparta e ad Atene), di una dialettica interna fra modelli educativi tradizionali e paradigmi formativi 'culti'. In particolare, si ripercorrono i caratteri principali della tradizione spartana e di quella ateniese in ambito educativo, per affrontare poi un esame sintetico di alcune prospettive inte…

paideiaSofistiAristofaneIsocratepedagogiaPlatoneSpartafilosofiaAteneSofocleeducazioneAristoteleSettore L-FIL-LET/04 - Lingua E Letteratura Latina
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Preavviso non lavorato e indennità di disoccupazione

2009

preavviso indennità disoccupazione
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Diversity of Isomerization Patterns and Protolytic Forms in Aminocarbene PdII and PtII Complexes Formed upon Addition of N,N′-Diphenylguanidine to Me…

2017

Reaction of the palladium(II) and platinum(II) isocyanide complexes cis-[MCl2(CNR)2] [M = Pd, R = C6H3(2,6-Me2) (Xyl), 2-Cl-6-MeC6H3, cyclohexyl (Cy), t-Bu, C(Me)2CH2(Me)3 (1,1,3,3-tetramethylbuth-1-yl abbreviated as tmbu); M = Pt, R = Xyl, 2-Cl-6-MeC6H3, Cy, t-Bu, and tmbu] with N,N′-diphenylguanidine (DPG) leads to DPG-derived metal-bound deprotonated acyclic diaminocarbene (ADC) species. This reaction occurs via a two-step process, involving the initial coupling of the guanidine with one of the isocyanides and leading to deprotonated monocarbene monochelated species, while the next addition grants the deprotonated bis-carbene bis-chelated metal compounds. DPG behaves as nucleophile, depr…

protolytic forms010405 organic chemistryStereochemistryIsocyanideOrganic ChemistrySubstituentchemistry.chemical_elementRegioselectivityaminocarbene complexes010402 general chemistry01 natural sciencesMedicinal chemistry0104 chemical sciencesdiversityInorganic Chemistrychemistry.chemical_compoundDeprotonationchemistryNucleophileisomerization patternsPhysical and Theoretical ChemistryGuanidineIsomerizationta116PalladiumOrganometallics
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CCDC 245603: Experimental Crystal Structure Determination

2004

Related Article: R.Herchel, R.Boca, M.Gembicky, J.Kozisek, F.Renz|2004|Inorg.Chem.|43|4103|doi:10.1021/ic035374i

tris((mu~2~-isocyano)-cyano-(NN''-bis(1-hydroxy-2-benzylidene)-17-diamino-4-azaheptane))-chromium(iii)-tri-iron(iii)Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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AMMORTIZZATORI SOCIALI E NUOVE PROSPETTIVE DI WELFARE

In linea con la costruzione di un Modello sociale europeo e con i principi di flexicurity e lotta all’esclusione sociale elaborati nel quadro della Strategia Europa 2020, lo studio ripercorre le tappe dell’auspicato processo di razionalizzazione/universalizzazione del sistema degli ammortizzatori sociali in Italia, al fine di conciliare le istanze di flessibilità del mercato del lavoro con un incremento della sicurezza sociale e dell’occupabilità. In particolare, si analizzano le rilevanti modifiche introdotte dalla legge n. 92 del 2012 (cd. Riforma Fornero), nonché quelle proposte, a distanza di neanche due anni, nell’ennesimo percorso di riforma prefigurato all’interno del cd. Jobs Act , …

welfare state modello sociale europeo flexicurity esclusione sociale Europa 2020 reddito minimo garantito tutela della disoccupazione ammortizzatori sociali autonomia collettiva riforma Fornero Jobs Act welfare mix.Settore IUS/07 - Diritto Del Lavoro
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Evaluation of biocidal potential of some plant species from the Mediterranean wild flora

wild flora biocidal inhibiition stimulation germination phytotoxic phytotoxicity extract extraction fungitoxic insecticidal Artemisia arborescens Rhus coriaria Dittrichia viscosa water extract bioassay essential oil Camphor Chamazulene and β-thujone Gallic acid nematodes Sesamin Ashantin Isocostic acid Carabrone TomentosinSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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Disociatīvās pieredzes, ķermeņa tēla uztveres un ruminācijas savstarpējās saistības sievietēm

2018

Pētījuma mērķis ir noskaidrot sakarības starp disociatīvās pieredzes izteiktību, ķermeņa tēla uztveri un rumināciju sievietēm. Pētījumā piedalījās 131 respondente (M=23,38; SD=3,88). Tika izmantotas trīs metodes – Disociācijas aptauja (Vanderlinden, van Dyck, Vanderreycken, Vertommen, & Verkes, 1993), Ķermeņa tēla uztveres aptauja (Slade 1996) un Ruminatīvo atbilžu skala (Treynor, Gonzalez & Nolen - Hoeksema, 2003). Pētījuma rezultāti parāda, ka ķermeņa tēla uztvere ir negatīvi statistiski nozīmīgi saistīta ar disociatīvās pieredzes izteiktību, t.i., jo izteiktāka ir disociatīvā pieredze, jo negatīvāka ir ķermeņa tēla uztvere. Pētījuma rezultāta parāda, ka ruminatīvā domāšana ir statistiski…

Ķermeņa tēla uztveres aptaujaDisociācijaDisociācijas aptaujaRuminācijaPsiholoģijaĶermeņa tēla uztvere
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