Search results for "ISOTOPE"

showing 10 items of 2232 documents

Measuring the 14C content in liquid scintillators

2016

We are going to perform a series of measurements where the 14C/12C ratio will be measured from several liquid scintillator samples with a dedicated setup. The setup is designed with the aim of measuring ratios smaller than 10−18. Measurements take place in two underground laboratories: in the Baksan Neutrino Observatory, Russia and in the Pyh¨asalmi mine, Finland. In Baksan the measurements started in 2015 and in Pyh¨asalmi they start in the beginning of 2015. In order to fully understand the operation of the setup and its background contributions a development of simulation packages has also been started. Low-energy neutrino detection with a liquid scintillator requires that the intrinsic …

low-energy neutrino detectionhiililiquid scintillatorsisotope ratio
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Elemental and isotope covariation of noble gases in mineral phases from Etnean volcanics erupted during 2001–2005, and genetic relation with peripher…

2008

Abstract During 2001–2005, Mount Etna was characterized by intense eruptive activity involving the emission of petrologically different products from several vents, which involved at least two types of magma with different degrees of evolution. We investigated the ratios and abundances for noble-gas isotopes in fluid inclusions trapped in olivines and pyroxenes in the erupted products. We confirm that olivine has the most efficient crystalline structure for preserving the pristine composition of entrapped gases, while pyroxene can suffer diffusive He loss. Both the minerals also experience noble gas air contamination after eruption. Helium isotopes of the products genetically linked to the …

magma degassing.geographygeography.geographical_feature_categoryOlivinefluid inclusionhelium isotopeTrace elementGeochemistryPyroxeneengineering.materialnoble gaseMantle (geology)Settore GEO/08 - Geochimica E VulcanologiaVolcanic rockGeophysicsVolcanoSpace and Planetary ScienceGeochemistry and PetrologyEarth and Planetary Sciences (miscellaneous)engineeringFluid inclusionsMetasomatismGeologymagma degassing
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Sedimentation and tropical vegetation changes in Southern Benin (West Africa), carbon-13 tracing of organic matter dynamics and fluctuations of the s…

2007

12 pages; International audience

mangrovepaleoenvironment[SDE.MCG]Environmental Sciences/Global Changes[ SDV.SA.SDS ] Life Sciences [q-bio]/Agricultural sciences/Soil study13C/12C isotope ratio[SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil study[ SDU.STU.ST ] Sciences of the Universe [physics]/Earth Sciences/Stratigraphy[ SDU.STU.GC ] Sciences of the Universe [physics]/Earth Sciences/Geochemistry[SDE.MCG] Environmental Sciences/Global Changes[ SDE.MCG ] Environmental Sciences/Global ChangesOuémé-Sô[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/Geochemistry[SDU.STU.ST]Sciences of the Universe [physics]/Earth Sciences/Stratigraphy[SDU.STU.GC] Sciences of the Universe [physics]/Earth Sciences/Geochemistry[SDU.STU.ST] Sciences of the Universe [physics]/Earth Sciences/StratigraphyBeninsea level fluctuation[SDV.SA.SDS] Life Sciences [q-bio]/Agricultural sciences/Soil studydelta faciesComputingMilieux_MISCELLANEOUS
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Direct mass measurements on neutron-deficient xenon isotopes with the ISOLTRAP mass spectrometer

2002

The masses of Xe isotopes with 124 A 114 have been measured using the ISOLTRAP spectrometer at the on-line mass separator ISOLDE/CERN. A mass resolving power of 500000 was chosen resulting in an accuracy of m 12 keV for all isotopes investigated. Con icts with existing mass data of several standard deviations were found. peerReviewed

massaspektrometriaatomic massesXenon isotopesPhysics::Instrumentation and Detectorspenning trapNuclear Experimentradioactive ions
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The influence of bacteria-dominated diets on Daphnia magna somatic growth, reproduction, and lipid composition

2012

We explored how dietary bacteria affect the life history traits and biochemical composition of Daphnia magna, using three bacteria taxa with very different lipid composition. Our objectives were to (1) examine whether and how bacteria-dominated diets affect Daphnia survival, growth, and fecundity, (2) see whether bacteria-specific fatty acid (FA) biomarkers accrued in Daphnia lipids, and (3) explore the quantitative relationship between bacteria availability in Daphnia diets and the amounts of bacterial FA in their lipids. Daphnia were fed monospecific and mixed diets of heterotrophic (Micrococcus luteus) or methanotrophic bacteria (Methylomonas methanica and Methylosinus trichosporium) and…

media_common.quotation_subjectDaphnia magnaHeterotrophApplied Microbiology and BiotechnologyMicrobiologyDaphniaBotanyAnimalsFood sciencereproductive and urinary physiologymedia_commonchemistry.chemical_classificationCarbon IsotopesBacteriaNitrogen IsotopesEcologybiologyReproductionfungiFatty acidbiology.organism_classificationLipidsDietCryptomonasFertilityDaphniachemistryPhytoplanktonMethylomonas methanicaReproductionBiomarkersBacteriaFEMS Microbiology Ecology
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Data from: Lake size and fish diversity determine resource use and trophic position of a top predator in high-latitude lakes

2015

Prey preference of top predators and energy flow across habitat boundaries are of fundamental importance for structure and function of aquatic and terrestrial ecosystems, as they may have strong effects on production, species diversity, and food-web stability. In lakes, littoral and pelagic food-web compartments are typically coupled and controlled by generalist fish top predators. However, the extent and determinants of such coupling remains a topical area of ecological research and is largely unknown in oligotrophic high-latitude lakes. We analyzed food-web structure and resource use by a generalist top predator, the Arctic charr Salvelinus alpinus (L.), in 17 oligotrophic subarctic lakes…

medicine and health carebenthicSalvelinus alpinusenergy mobilizationstable isotope analysisMedicineLife sciences
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Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer

2019

There is still a great unmet medical need concerning diagnosis and treatment of breast cancer which could be addressed by utilizing specific molecular targets. Tumor-associated MUC1 is expressed on over 90 % of all breast cancer entities and differs strongly from its physiological form on epithelial cells, therefore presenting a unique target for breast cancer diagnosis and antibody-mediated immune therapy. Utilizing an anti-tumor vaccine based on a synthetically prepared glycopeptide, we generated a monoclonal antibody (mAb) GGSK-1/30, selectively recognizing human tumor-associated MUC1. This antibody targets exclusively tumor-associated MUC1 in the absence of any binding to MUC1 on health…

medicine.drug_classEstrogen receptorMUC1Breast NeoplasmsMice TransgenicDeferoxamineMonoclonal antibody89Zr03 medical and health sciences0302 clinical medicineBreast cancerIn vivoCell Line TumorBiomarkers TumormedicineAnimalsHumansTissue Distributionskin and connective tissue diseasesMUC1Triple-negative breast cancermAbRadioisotopesMice Inbred BALB Cbiologybusiness.industryMucin-1breast cancer diagnosisAntibodies MonoclonalCancerGeneral MedicinePrognosismedicine.diseaseImmunohistochemistryMice Inbred C57BLPositron-Emission Tomographybiology.proteinCancer researchFemale030211 gastroenterology & hepatologyZirconiumAntibodybusinessResearch PaperInternational Journal of Medical Sciences
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16α-Iodo-3,17β-estradiol: A stable ligand for estrogen receptor determinations in tissues with high 17β-hydroxysteroid dehydrogenase activity

1983

Recently, the successful synthesis of radioiodinated 16 alpha-iodo-3,17 beta-estradiol-[125I] [125I]E2 was reported [1]. This new ligand has similar binding characteristics to the estrogen receptor (ER) [2-5] as the currently used tritium labeled estradiol [3H]E2. However, it offers several advantageous features: (a) high specific activity (theoretically 2,000 Ci/mmol) [1]; (b) minor problems with radioactive waste due to its short half life and (c) the possibility of simultaneous determination of ER and progesterone receptors (PgR) by double labeling with [125I]E2 and [3H]R5020 [6, 7]. As we are presently trying to determine ER and PgR in human placental cytosols we were interested in the …

medicine.medical_specialty17-Hydroxysteroid DehydrogenasesPlacentaEstrogen receptorEstroneOvaryLigandsTritiumEndometriumBiochemistryIodine Radioisotopeschemistry.chemical_compoundEndocrinologyPregnancyInternal medicinemedicineHumansHydroxysteroid dehydrogenaseReceptorEstradiolChemistryHalf-lifeLigand (biochemistry)Kineticsmedicine.anatomical_structureEndocrinologyReceptors EstrogenBiochemistryFemalehormones hormone substitutes and hormone antagonistsJournal of Steroid Biochemistry
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Characterization of adenosine receptors in guinea-pig isolated left atria

1989

1. The effects of purinergic stimulation on action potential, force of contraction, 86Rb efflux and 45Ca uptake were investigated in guinea-pig left atria. 2. Adenosine exerted a negative inotropic effect which was antagonized by adenosine deaminase but enhanced by dipyridamole. 3. The negative inotropic effect of adenosine was mimicked by 5'-(N-ethyl)-carboxamido-adenosine (NECA) and the isomers of N6-(phenyl-isopropyl)-adenosine, R-PIA and S-PIA. NECA and R-PIA were about 100 times more potent than adenosine, whereas R-PIA was about 100 times more potent than S-PIA. 4. The inotropic effects of adenosine (in the presence of dipyridamole), NECA, R-PIA and S-PIA were competitively antagonize…

medicine.medical_specialtyAdenosineContraction (grammar)Guinea PigsPopulationAction PotentialsStimulationAdenosine-5'-(N-ethylcarboxamide)In Vitro TechniquesMembrane PotentialsAdenosine deaminaseTheophyllineInternal medicinemedicineAnimalseducationPharmacologyMembrane potentialeducation.field_of_studybiologyChemistryCalcium RadioisotopesMyocardiumPurinergic receptorReceptors PurinergicHeartDipyridamoleMyocardial ContractionAdenosineAdenosine receptorElectric StimulationEndocrinologyPhenylisopropyladenosinecardiovascular systembiology.proteinRubidium RadioisotopesResearch Articlemedicine.drugBritish Journal of Pharmacology
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Prenatal diagnosis of mucolipidosis II (I-cell disease)

1976

A pregnancy at risk for mucolipidosis II (I-cell disease) was monitored in which an affected fetus was predicted on the basis of the analyses of lysosomal hydrolases in amniotic fluid and cultured amniotic fluid cells, and by the demonstration of an excessive accumulation of [35S] sulfate-labeled glycosaminoglycans in cultured amniotic cells. This diagnosis was confirmed by performing enzyme assays and [35S] sulfate incorporation studies on material derived from the aborted fetus.

medicine.medical_specialtyAmniotic fluidHydrolasesPrenatal diagnosisSulfur RadioisotopesAndrologyGlycosaminoglycanPregnancyPrenatal DiagnosisInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingCells CulturedGlycosaminoglycansPregnancyFetusbusiness.industryMucolipidosisAborted FetusGeneral MedicineMucopolysaccharidosesAmniotic Fluidmedicine.diseaseEndocrinologyPediatrics Perinatology and Child HealthFemaleI-cell diseaseLysosomesbusinessEuropean Journal of Pediatrics
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