Search results for "ISR"

Search for quarks in proton-proton interactions at √s = 52.5 GeV

1978

The results of an experiment to search for quarks in pp collisions, at a total centre-of-mass energy √s = 52.5 GeV, are reported. The experiment was sensitive to fractionally charged particles with 0.035e ⩽ |Q| ⩽ 0.67e,β =v/c ⩾ 0.1, and masses up to 21 GeV/c2. The 90% confidence level on the ratio «quark flux/charged-particle flux» is 5.11 · 10−11 for |Q| = 1/3e. This value holds true for particles produced with a mean transverse momentum of 0.4 GeV/c.

Early modern state formation in the margins? A review of early modern popular politics and limited royal power in the Polish-Lithuanian Commonwealth …

2017

The traditional historiography of early modern state-building has usually followed the western European paradigm of historiography, the usual models being France, England, Brandenburg-Prussia and Sweden. Regions that do not follow this paradigm have simply been left out and labeled “backward” or as “lagging behind”. In this literary review, our focus is on two different and rather surprising cases of early modern state formation: the Polish-Lithuanian Commonwealth and the Spanish colonial empire in Latin America. By following the scholarship on these two large conglomerates, we focus on two scholarly concepts: the idea of early modern realms as composite/conglomerate states, and state forma…

BBS1 Mutations in a Wide Spectrum of Phenotypes Ranging From Nonsyndromic Retinitis Pigmentosa to Bardet-Biedl Syndrome

2012

OBJECTIVE: To investigate the involvement of the Bardet-Biedl syndrome (BBS) gene BBS1 p.M390R variant in nonsyndromic autosomal recessive retinitis pigmentosa (RP). METHODS: Homozygosity mapping of a patient with isolated RP was followed by BBS1 sequence analysis. We performed restriction fragment length polymorphism analysis of the p.M390R allele in 2007 patients with isolated RP or autosomal recessive RP and in 1824 ethnically matched controls. Patients with 2 BBS1 variants underwent extensive clinical and ophthalmologic assessment. RESULTS: In an RP proband who did not fulfill the clinical criteria for BBS, we identified a large homozygous region encompassing the BBS1 gene, which carrie…

EmPeCemos: un programa multicomponente para la prevención indicada de los problemas de conducta y el abuso de drogas

2009

En la última década, un amplio número de investigaciones ha permitido constatar la existencia de trayectorias de desarrollo desadaptativas, asociadas a problemas de conducta de inicio temprano. Estas trayectorias, en las que se implica una compleja cadena de factores familiares, escolares y socioemocionales, dan lugar a desajustes comportamentales crónicos y severos, de difícil tratamiento, incluyendo comportamientos antisociales y abuso de drogas. Por ello, la investigación en prevención subraya la necesidad de una intervención temprana que, actuando sobre los individuos en alto riesgo y su entorno, permita detener el avance hacia patrones severos de desadaptación. En esta línea, se desarr…

Synthesis of a new class of pyrrolo[3,4-h]quinazolines with antimitotic activity

2014

Abstract A new series of pyrrolo[3,4- h ]quinazolines was conveniently prepared with a broad substitution pattern. A large number of derivatives was obtained and the cellular cytotoxicity was evaluated in vitro against 5 different human tumor cell lines with GI 50 values reaching the low micromolar level (1.3–19.8 μM). These compounds were able to induce cell death mainly by apoptosis through a mitochondrial dependent pathway. Selected compounds showed antimitotic activity and a reduction of tubulin polymerization in a concentration-dependent manner. Moreover, they showed anti-angiogenic properties since reduced in vitro endothelial cell migration and disrupted HUVEC capillary-like tube net…

A 5-Year Follow-Up Study of Psychotherapy

1990

This 5-year study examined students who were in individual psychotherapy. The specific interest of the study was in the stability of changes in their self-concept after psychotherapy. Students who were patients at the Dental Health Care Unit were used as a control group. Self-concept was measured by a multidimensional measure which consisted of four dependent variables: symptoms, Beck’s Depression Inventory, self-image test and general progress during therapy. Changes in self-concept were presented as change profiles which showed that statistically significant changes had occurred in the experimental group during the 5-year follow-up study. However, the profile of the control group remained…

Climate Change, Uncertainty and Ethical Superstorms

2021

I argue that one of the most urgent tasks of geoethics is how to deal with climate change in a just and equitable way. At worst, our current path could lead to multi-metre sea-level rise, increases in storms and climate extremes, causing devastating social disruption and economic consequences. I present some alternatives on how to handle this alarming prospect, arguing that we cannot condense our decision-making on climate change into numerical calculations, but should instead make ethical judgements. The commonly used expected utility maximation can be considered a gamble on future generations’ expense for the benefit of the current ones. Thus, from a Rawlsian perspective, we will instead …

Israel vs. palestiinalaiset: konfliktin transformaatio vai pintaretoriikkaa? : pääministeri Jitzhak Rabinin puheiden ja haastatteluiden kautta tulkit…

2003

International migration, remittances, and the human capital formation of Egyptian children

2013

We study the roles that migration and remittances play in the human capital formation of children in Egypt. Our estimations reveal a significant association between remittances and human capital formation: the higher the probability of receipt of remittances, the higher the probability of school enrollment, and the older the age at which children enter the labor force. Although, with regard to the likelihood of school enrollment and the age of the first participation in the labor force, the family disruption effect of migration dominates the income effect of remittances, the likelihood of labor force participation decreases even in households from which both parents migrated.

Il sistema costituzionale e il fattore religioso in Israele

2013

Il fenomeno religioso costituisce un elemento identificativo dello Stato israeliano, caratterizzandone gli aspetti istituzionali, il sistema delle fonti, influenzando il contenuto della normativa legislativa e condizionando l’attività giudiziaria spesso alla ricerca di un necessario contemperamento tra le diverse istanze sociali non sempre rappresentate adeguatamente dalle scelte del Parlamento e degli organi governativi. L’articolo, nell’individuare i diversi ambiti in cui l’influenza del fattore religioso assume una significativa rilevanza, nel rapporto tra religione ed educazione, la protezione dei luoghi sacri, il finanziamento ad istituzioni religiose, farà riferimento alle decisioni d…