Search results for "ITALY"

showing 10 items of 2893 documents

Effect of a Natural Supplement Containing Curcuma Longa, Guggul, and Chlorogenic Acid in Patients With Metabolic Syndrome

2015

The impact of a natural supplement (Kepar; Rikrea, Italy), containing several plant extracts such as curcuma longa, silymarin, guggul, chlorogenic acid, and inulin, was evaluated in 78 patients with metabolic syndrome (MetS; 45 men; age: 62 ± 9 years). Kepar at a dose of 2 pills/d was given for 4 months as add-on therapy to the ongoing treatment, maintained at fixed doses for the entire study. Anthropometric variables, plasma lipids, glucose parameters, and oxidative stress were measured at baseline and after 4 months. We found significant reductions in body weight (from 81.1 ± 13.5 to 79.4 ± 12.5 kg, P < .0001), body mass index (from 29.6 [23.7] to 29.3 [21.9] kg/m2, P = .001), and wai…

Blood GlucoseMaleTime FactorssilymarinPilot Projectsmedicine.disease_causelaw.inventionchemistry.chemical_compoundlawWeight lossPlant GumsPlant GumCommiphoraCurcuma longainulinbiologyMetabolic Syndrome XMedicine (all)Middle AgedTreatment OutcomeItalyFemalemedicine.symptomCardiology and Cardiovascular MedicineHumanmedicine.medical_specialtyTime Factorchlorogenic acidmetabolic syndromePlant ExtractCurcumaChlorogenic acidguggulInternal medicineWeight LossmedicineHumansPilot ProjectCurcumaAgedDietary Supplementoxidative strePlants MedicinalPlant Extractsbusiness.industryCholesterolcholesterolBiomarkerbiology.organism_classificationmedicine.diseaseWeight LoOxidative Stressnatural supplementEndocrinologychemistryDietary SupplementsMetabolic syndromePhytotherapybusinessBody mass indexBiomarkersOxidative stressPhytotherapyAngiology
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Efficacy of dulaglutide on vascular health indexes in subjects with type 2 diabetes: a randomized trial

2021

Abstract Background Recent cardiovascular outcome trials have shown significant reductions in major cardiovascular (CV) events with glucagon-like peptide (GLP)-1 receptor agonists. Additionally, adjunctive surrogates for cardiovascular risk validated by some studies include arterial stiffness and endothelial function indexes. To date, no randomized trial has addressed the possible effects of antidiabetic interventional drugs such as GLP1 agonists on endothelial and arterial stiffness indexes as surrogate markers of vascular damage. Aims We aimed to evaluate metabolic efficacy and surrogate vascular efficacy endpoints of once-weekly dulaglutide (1.5 mg) plus traditional antidiabetic treatmen…

Blood GlucoseMalelcsh:Diseases of the circulatory (Cardiovascular) systemSettore MED/09 - Medicina InternaTime FactorsEndocrinology Diabetes and MetabolismGlucagon-Like PeptidesBlood PressureType 2 diabetesGastroenterologylaw.inventionRandomized controlled triallawPulse wave velocityOriginal InvestigationDiabetesMiddle AgedLipidsVasodilationTreatment OutcomeItalyDrug Therapy CombinationFemaleCardiology and Cardiovascular Medicinemedicine.drugmedicine.medical_specialtyRecombinant Fusion ProteinsIncretinsGlucagon-Like Peptide-1 ReceptorVascular StiffnessDiabetes mellitusInternal medicinemedicineHumansHypoglycemic AgentsDulaglutideAngiologyAgedVascular healthGlycated Hemoglobinbusiness.industrymedicine.diseasedulaglutide diabetes arterial stiffnessImmunoglobulin Fc FragmentsBlood pressureDiabetes Mellitus Type 2lcsh:RC666-701Arterial stiffnessDulaglutidebusinessBiomarkersCardiovascular Diabetology
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Prevalence of type 2 diabetes among patients with hypertension under the care of 30 Italian clinics of hypertension: results of the (Iper)tensione an…

2008

BACKGROUND AND PURPOSE Hypertension is known to be highly prevalent among patients with diabetes and associated with an increased risk of cardiovascular damage. In contrast, relatively few investigations have addressed the prevalence of diabetes among patients with hypertension. The purpose of the present study was to examine the prevalence of type 2 diabetes, the effectiveness of hypertension and diabetes control and the association with other cardiovascular risk factors and previous cardiovascular diseases in a cohort of patients with hypertension referred to 30 hospital outpatient clinics for the treatment of hypertension. METHODS AND PATIENTS Patients were considered as having diabetes …

Blood GlucoseMalemedicine.medical_specialtyhypertensionPhysiologyBlood Pressurediabetes; hypertension; prevalenceType 2 diabetesAmbulatory Care FacilitiesCohort Studieschemistry.chemical_compoundRisk FactorsInternal medicineDiabetes mellitusPrevalenceInternal MedicinemedicineHumansOutpatient clinicAgedCreatinineGlucose tolerance testDiabete di tipo 2 ipertensione arteriosamedicine.diagnostic_testdiabetesbusiness.industryGlucose Tolerance TestMiddle Agedmedicine.diseasediabetes; hypertensionBlood pressureEndocrinologyDiabetes Mellitus Type 2ItalychemistryFemaleMicroalbuminuriaCardiology and Cardiovascular MedicinebusinessCohort study
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Subclinical atherosclerosis and history of cardiovascular events in Italian patients with rheumatoid arthritis: Results from a cross-sectional, multi…

2017

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Blood GlucoseMalerheumatoid arthritisCross-sectional studyType 2 diabetesTriglycerideArthritis Rheumatoid0302 clinical medicineRisk FactorsCardiovascular DiseasePrevalence030212 general & internal medicineMyocardial infarctionStrokeSubclinical infectionAged 80 and overMetabolic SyndromeMetabolic Syndrome XGeneral MedicineMiddle Agedinflammatory processCholesterolItalyCardiovascular DiseasesRheumatoid arthritisAtherosclerosiHypertensionComputingMethodologies_DOCUMENTANDTEXTPROCESSINGFemaleHumanResearch ArticleAdultmedicine.medical_specialtyAdolescentsubclinical atherosclerosisObservational Study03 medical and health sciencesYoung Adultcardiovascular eventsInternal medicinemedicineHumansTriglyceridesAged030203 arthritis & rheumatologyCross-Sectional Studiebusiness.industryRisk Factor6900medicine.diseaseAtherosclerosisCross-Sectional StudiesDiabetes Mellitus Type 2Physical therapyMetabolic syndromebusinessRheumatismtraditional cardiovascular risk factorMedicine
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Serological screening for Leishmania infantum in asymptomatic blood donors living in an endemic area (Sicily, Italy)

2005

The purpose of our study was to assess whether Leishmania infantum parasitemia occurs in asymptomatic Leishmania-seropositive subjects. Samples from 500 blood donors were tested using an enzyme-linked immunosorbent assay (ELISA). Anti-Leishmania antibodies were not found in any sample. Our findings suggest that the risk of L. infantum transmission by blood transfusion in Sicily is very low.

Blood transfusionmedicine.medical_treatmentAntibodies ProtozoanBlood DonorsParasitemiaAsymptomaticSerologyleishmaniaparasitic diseasesmedicineAnimalsHumansLeishmania infantumbiologyTransmission (medicine)business.industryHematologybiology.organism_classificationmedicine.diseaseVisceral leishmaniasisItalyImmunologybiology.proteinLeishmaniasis VisceralLeishmania infantumAntibodymedicine.symptombusinessTransfusion and Apheresis Science
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First case in Italy of acquired resistance to oseltamivir in an immunocompromised patient with influenza A/H1N1v infection

2010

A pandemic influenza A/H1N1v strain with the neuraminidase H274Y mutation was detected in nasal secretions of a 2-year-old leukemic patient with influenza-like illness after 18 days of treatment with oseltamivir. At baseline, no drug-resistant virus was found, while 4 days after treatment initiation a mix- ture of wild-type and mutated virus was detected. After treatment interruption, the wild type influenza virus re-emerged and became prevalent in nasal secretions after a few days, suggesting the lower fitness of the mutated virus strain. The patient slowly improved concurrently with a decrease in virus load, which resulted negative 42 days after diagnosis. No other drug-resistant influenz…

Bodily SecretionsvirusesResistanceDrug ResistanceSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causePandemic H1N1v Oseltamivir Resistancechemistry.chemical_compoundInfluenza A Virus H1N1 SubtypePandemicInfluenza A virusInfluenza A VirusViralChildViral LoadTreatment OutcomeInfectious DiseasesItalyChild PreschoolRNA ViralFemaleViral diseaseViral loadH1N1vSequence AnalysisH1N1v; Oseltamivir; Pandemic; Resistance; Amino Acid Substitution; Antiviral Agents; Bodily Secretions; Child Preschool; Female; Humans; Immunocompromised Host; Influenza A Virus H1N1 Subtype; Influenza Human; Italy; Molecular Sequence Data; Mutation Missense; Neuraminidase; Nose; Oseltamivir; RNA Viral; Sequence Analysis DNA; Treatment Outcome; Viral Load; Viral Proteins; Withholding Treatment; Drug Resistance Viral; Virology; Infectious DiseasesHumanOseltamivirMolecular Sequence DataMutation MissenseNeuraminidaseBiologyNoseAntiviral AgentsVirusresistanceImmunocompromised HostViral ProteinsOseltamivirVirologyDrug Resistance ViralInfluenza HumanmedicineHumansH1N1 SubtypePreschoolInfluenza-like illnessPandemicSequence Analysis DNADNAVirologyInfluenzaInfluenza; A/H1N1v; Oseltamivir; resistancechemistryAmino Acid SubstitutionWithholding TreatmentMutationbiology.proteinRNAA/H1N1vMissenseNeuraminidase
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An Anthropometric Analysis of Seated and Standing People

2012

Thermal radiative exchanges of the human body with surrounding surfaces play an essential role in describing the thermal conditions of people in a given environment. Moreover, they could be induced by, among other causes, the presence of high intensity radiant sources, like lighting spots or infrared heating panels. This implies that a suitable set of radiation data related to human body anthropometry is required. This set of data mainly comprises the body surface area, the clothing area factor, the effective radiation area factor, and projected area factors. Several analytical or experimental methods may be utilized in order to compute these parameters. A detailed description of the most c…

Body surface areaeducation.field_of_studyDry Heat Exchanges clothing area factor effective radiation area factor projected area factors southern Italy.Settore ING-IND/11 - Fisica Tecnica Ambientalebusiness.industrySample (material)PopulationAnthropometryClothingStatisticsProjected areaRadiative transferEnvironmental scienceeducationSet (psychology)business
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Floristic and phytosociological features of the Brachypodium rupestre communities in Italy

2018

The pale green dense Tor-grass (Brachypodium rupestre) tufts are a quite distinctive aspect of the Italian grassland pattern of the colline and submontane belts. B. rupestre is used to be found in secondary grasslands both in natural environments and in some aspects of the post-coltural environments such as forest clearances, abandoned terraced and extensive pastures. In northern Italy (Alps, Prealps and northern Apennines) B. rupestre has only sporadically been considered in the grasslands syntaxonomic frameworks. On the contrary it occurs in those regarding the central Italy where several semi-natural and post-coltural grassland associations (e.g. Polygalo flavescentis-Brachypodietum, Gal…

Brachypodium rupestreSettore BIO/03 - Botanica Ambientale E ApplicatagrasslandssyntaxonomyBrachypodium rupestre Italy grasslands
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Time trends of benign/malignant breast biopsy ratios a multicenter Italian study.

1996

Aims and background Although they have been decreasing over time due to improved specificity of diagnostic assessment, benign biopsies of the breast are still common. Benign biopsies should be regarded as negative events, due to their economical and psychological cost and their possible negative impact on cosmesis and on further diagnostic evaluation. Methods Retrospective data on benign/malignant breast biopsies ratio (B/M) were collected in 9 Italian centers for a period of 10-15 years. The time trend of B/M and its association to age or to single centers was evaluated. Results Overall 31,001 cases were considered. A strong association of B/M to age was evident (average B/M values were 5.…

Breast biopsyAdultMaleCancer Researchmedicine.medical_specialtyMultivariate analysisBiopsyBreast NeoplasmsGastroenterologyBreast DiseasesAge DistributionInternal medicinemedicineOdds RatioHumansRetrospective StudiesGynecologymedicine.diagnostic_testTime trendsbusiness.industryCosmesisRetrospective cohort studyGeneral MedicineOdds ratioMiddle AgedConfounding effectSettore MED/18 - Chirurgia GeneraleLogistic ModelsOncologyItalyMultivariate AnalysisDiagnostic assessmentbreast carcinoma diagnosis specificityFemalebusinessTumori
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The missed Constitutional Reform and its possible impact on the sustainability of the Italian National Health Service.

2017

THE MISSED CONSTITUTIONAL REFORM AND ITS POSSIBLE IMPACT ON THE SUSTAINABILITY OF THE ITALIAN NATIONAL HEALTH SERVICE The rejection of the Constitutional Law Bill No.1429-D in the December 2016 referendum, has stimulated a cause for reflection on current health legislation and the future prospects of the Italian National Health Service; also in the context of the recent approval of the new Essential Levels of care (LEA) and other relevant laws approved by the Parliament. This article analyzes possible future legislative and organizational scenarios with particular regard to issues related to National health system’s sustainability. (www.actabiomedica.it)

Briefing onItalyNational Health ProgramsHealth Care ReformHumansActa bio-medica : Atenei Parmensis
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