Search results for "IXO"
showing 10 items of 167 documents
The role of maternal effects in host-parasite interactions: examination of the development of the immune defense in a colonial seabird, the black-leg…
2004
One of the main aims of evolutionary biology is to understand the mechanisms responsible for the phenotypic variation on which natural selection can act. Maternal effects occur when a mother's phenotype or her environment influence her offspring's phenotype. Despite the importance of such effects for the ecology of host-parasite interactions, their role has been relatively neglected to date. In this thesis, we examined how mothers influence the immune defense of their young in an environment that varies in space and time. This work has primarily focused on a colonial seabird, the black-legged kittiwake (Rissa tridactyla). Using this model, we have first shown that specific maternal antibodi…
Rodent host population dynamics drive zoonotic Lyme Borreliosis and Orthohantavirus infections in humans in Northern Europe
2021
Zoonotic diseases, caused by pathogens transmitted between other vertebrate animals and humans, pose a major risk to human health. Rodents are important reservoir hosts for many zoonotic pathogens, and rodent population dynamics affect the infection dynamics of rodent-borne diseases, such as diseases caused by hantaviruses. However, the role of rodent population dynamics in determining the infection dynamics of rodent-associated tick-borne diseases, such as Lyme borreliosis (LB), caused by Borrelia burgdorferi sensu lato bacteria, have gained limited attention in Northern Europe, despite the multiannual abundance fluctuations, the so-called vole cycles, that characterise rodent population d…
Caracterización, tradición y fuentes caballerescas del personaje de Merlín en el Quijote
2010
RESUMEN Este artículo estudia la caracterización de Merlín en el Quijote de Miguel de Cervantes. Para ello, se analizan las dos apariciones del encantador, en la cueva de Montesinos y en la cacería con los duques. Para comprender la caracterización de Merlín y la razón de su aparición en la novela cervantina, se parte de los atributos del mago en las novelas de caballerías castellanas del Siglo de Oro y en otras fuentes caballerescas. Además, se explican muchos de los atributos de la caracterización de Merlín en la obra Cervantes, a partir de su larga tradición que se remonta a la Eda Media. PALABRAS CLAVE: Merlín, el Quijote, novelas de caballerías, fuentes. ABSTRACT This article studies M…
Fast and accurate methodology for direct mercury determination in hair and nails
2015
AbstractA solvent-free, easy, fast and waste-free methodology was developed for the determination of total mercury levels in hair and nails. Samples were taken from several volunteers and directly analysed, with levels of mercury in the range between 0.5 and 8 ng/mg. The influence of quantity of hair, as well as the addition of small amount of solvent and the necessity of previous treatment were studied. Also, a history of mercury exposure was provided by the distance of the hair from the scalp of each volunteer, the results of which were correlated with fish consumption. Furthermore, a short study of mercury in nails was carried out and correlated to the results from hair mercury levels. A…
Metabolic plasticity of mixotrophic algae is key for their persistence in browning environments
2022
Light availability is the main regulator of primary production, shaping photosynthetic communities and their production of ecologically important biomolecules. In freshwater ecosystems, increasing dissolved organic carbon concentrations, commonly known as browning, leads to lower light availability and the proliferation of mixotrophic phytoplankton. Here, a mixotrophic algal species (Cryptomonas sp.) was grown under five increasing dissolved organic carbon concentrations to uncover the plastic responses behind the success of mixotrophs in browning environments and their effect in the availability of nutritionally important biomolecules. In addition to the browning treatments, phototrophic, …
Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner
2004
The serotonin type 3 (5-HT(3)) receptor is the only ligand-gated ion channel receptor for serotonin (5-HT). 5-HT(3) receptors play an important role in modulating the inhibitory action of dopamine in mesocorticolimbic brain regions. Neuroleptic drugs are commonly thought to exert their psychopharmacological action mainly through dopamine and serotonin type 2 (5-HT(2)) receptors. Except for clozapine, a direct pharmacological interaction of neuroleptics with 5-HT(3) receptors has not yet been described. Using the concentration-clamp technique, we investigated the effects of flupentixol, various phenothiazines, haloperidol, clozapine and risperidone on Na(+)-inward currents through 5-HT(3) re…
Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei of Appendiceal Origin: A Single Center Experience.
2021
Background: Pseudomyxoma peritonei (PMP) originating from appendiceal mucinous neoplasm is a rare peritoneal malignancy characterized by the progressive intraperitoneal accumulation of mucus leading to death if left untreated. In recent years, cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) offered increased survival rates. This study aims to identify the clinical, pathological, and surgical features influencing safety and survival outcomes of patients undergoing CRS and HIPEC for PMP of appendiceal origin.Methods: A retrospective analysis of all patients undergoing CRS and HIPEC for PMP of appendiceal origin from January 2015 to May 2019 was cond…
Dopaminergic modulation of evoked vasopressin release from the isolated neurohypophysis of the rat
1982
1. Neurointermediate lobes of rat pituitaries were incubated in Locke or Krebs solution, and the vasopressin released into the medium was assayed on the blood pressure of the pithed rat or by a radioimmunological procedure. Release of vasopressin over resting levels was evoked either by incubation with 60 mM KCl (high K) solution or by electrical stimulation of the pituitary stalk. Two different kinds of electrical stimulation were carried out. Procedure A (1 ms, 10 Hz, 5 times for 1 min within 10 min) induced a vasopressin overflow which was greatly calcium-dependent but only insignificantly sensitive to tetrodotoxin (TTX). Procedure B (0.2 ms, 15 Hz, 10 s trains with 10 s intervals for 10…
Mecanismes implicats en l'homeòstasi i desintoxicació de metalls en peixos de la Mar Mediterrània
2015
El medi marí està exposat a canvis físics i químics que principalment són antropogènics. Cal destacar alguns canvis com l'augment de la temperatura de l'aigua i la presència de metalls els quals poden afectar negativament l'estat de salut dels organismes residents. Les particulars característiques del Mar Mediterrani en quant a la elevada densitat de població costanera i reduïda circulació d’aigua, entre altres, fa d’aquesta mar un lloc molt vulnerable front als contaminants. La heterogeneïtat que per la presencia de contaminats en general, i metalls tòxics en particular, representa la proximitat a la costa o la profunditat fa necessari estudiar la contaminació i els seus efectes en cadascú…
Patogēnu prevalence migrējošo putnu ērcēs 2018. gadā Papē
2022
Šajā pētījumā ir analizēta Borrelia spp., Babesia spp., Rickettsia spp., Anaplasma phagocytophilum un Ca. N. mikurensis prevalence 2018. gadā Papē ievāktās migrējošo putnu ērcēs. Izmantojot PCR metodes tika analizētas 788 Ixodes ricinus ērces, kas nolasītas no 369 putniem. Kur nepieciešams, patogēnus noteica līdz sugas līmenim, izmantojot sekvencēšanu. Tika konstatēts, ka minētie patogeni ir sastopami ar šādu prevelenci: Borrelia sp. – 7,86 %, Babesia sp. – 0,63 %, Rickettsia spp. – 11,41 %, A. phagocytophilum – 0,76 %, un Ca. N. mikurensis – 4,06 %. Proporcionāli visvairāk ērču bija Turdus ģints, Erithacus rubecula un Acrocephalus ģints putniem, kuru ligzdošanas un barošanās uzvedība veici…