Search results for "IgG4"
showing 6 items of 6 documents
T cell Polarization toward T(H)2/T(FH)2 and T(H)17/T(FH)17 in Patients with IgG4-related Disease
2017
International audience; IgG4-related disease (IgG4-RD) is a fibro-inflammatory disorder involving virtually every organ with a risk of organ dysfunction. Despite recent studies regarding B cell and T cell compartments, the disease's pathophysiology remains poorly understood. We examined and characterized subsets of circulating lymphocytes in untreated patients with active IgG4-RD. Twenty-eight consecutive patients with biopsy-proven IgG4-RD were included in a prospective, multicentric study. Lymphocyte's subsets were analyzed by flow cytometry, with analysis of T(H)1/T(H)2/T(H)17, T-FH cells, and cytokine release by peripheral blood mononuclear cells. Results were compared to healthy contro…
Ophthalmic manifestations in IgG4-related disease
2017
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Endoscopic ultrasonography findings in autoimmune pancreatitis
2011
Endoscopic ultrasonography is an established diagnostic tool for pancreatic masses and chronic pancreatitis. In recent years there has been a growing interest in the worldwide medical community in autoimmune pancreatitis (AIP), a form of chronic pancreatitis caused by an autoimmune process. This paper reviews the current available literature about the endoscopic ultrasonographic findings of AIP and the role of this imaging technique in the management of this protean disease.
IgG4 Related Syndrome: Another Multiorgan Disease in the Interest Field of Internal Medicine.
2016
BACKGROUND: IgG4-related disease is a rare, clinical and pathologic disease entity of unknown etiology. Its main features are increased serum concentrations of IgG4 > 1,35 g/l, lymphocyte and IgG4+plasma-cell infiltration within tissues, fibrosis or sclerosis. The classical presentation of IgG4-RSD is pancreatitis which is combined with the involvement of biliary ducts in 74 percent of patients. Extrapancreatic manifestations include: abdominal or mediastinal lymphadenopathy; the involvement of salivary glands and lacrimal glands, kidneys, lung, retroperitoneum. Since IgG4-related disease is a multiorgan lymphoproliferative syndrome, it requires a careful differential diagnosis from othe…
T Cell Polarization toward T
2016
IgG4-related disease (IgG4-RD) is a fibro-inflammatory disorder involving virtually every organ with a risk of organ dysfunction. Despite recent studies regarding B cell and T cell compartments, the disease’s pathophysiology remains poorly understood. We examined and characterized subsets of circulating lymphocytes in untreated patients with active IgG4-RD. Twenty-eight consecutive patients with biopsy-proven IgG4-RD were included in a prospective, multicentric study. Lymphocytes’ subsets were analyzed by flow cytometry, with analysis of TH1/TH2/TH17, TFH cells, and cytokine release by peripheral blood mononuclear cells. Results were compared to healthy controls and to patients with primary…
Pārtikas alergēnu kvantitatīva izpēte atopiskā dermatīta pacientiem pieaugušo vecumā
2015
Tēmas aktualitāte: AD ir hroniska recidivējošā ādas iekaisuma slimība, kas stipri ietekmē dzīves kvalitāti. Pēdējo gadu laikā gadījumu skaits turpina palielināties. AD pacientiem bieži ir arī pārtikas alerģijas, kas pasliktina pacienta stāvokli, jo provocē klīnisko simptomu rašanos. Darba mērķis: Izpētīt kuri IgG4 paneļi visbiežāk sastopami pacientiem ar atopisko dermatītu. Materiāli un metodes: Tika veiksts retrospektīvs pētījums, kura laikā tika izskatītas 57 laboratorisko analīžu atbilžu veidlapas. Tika ievērota datu konfidencialitāte. Pētījuma laikā tika atlasīti un izskatīti 57 gadīgumi vecumā no 18-50 gadiem. Pacientu vidējais vecums ir 28,5 gadi ar standartnovirzi 7,0 gadi. Tika pētī…