Search results for "IgG"
showing 10 items of 1389 documents
Experimental constraints on the coupling of the Higgs boson to electrons
2015
In the standard model (SM), the coupling of the Higgs boson to electrons is real and very small, proportional to the electron mass. New physics could significantly modify both real and imaginary parts of this coupling. We discuss experiments which are sensitive to the Higgs-electron coupling and derive the current bounds on new physics contributing to this coupling. The strongest constraint follows from the ACME bound on the electron electric dipole moment (EDM). We calculate the full analytic two-loop result for the electron EDM and show that it bounds the imaginary part of the Higgs-electron coupling to be less than 1.7 x 10^-2 times the SM electron Yukawa coupling. Deviations of the real…
gg→HH : Combined uncertainties
2021
In this paper we discuss the combination of the usual renormalization and factorization scale uncertainties of Higgs-pair production via gluon fusion with the novel uncertainties originating from the scheme and scale choice of the virtual top mass. Moreover, we address the uncertainties related to the top-mass definition for different values of the trilinear Higgs coupling and their combination with the other uncertainties.
Analytic results for virtual QCD corrections to Higgs production and decay
2006
We consider the production of a Higgs boson via gluon-fusion and its decay into two photons. We compute the NLO virtual QCD corrections to these processes in a general framework in which the coupling of the Higgs boson to the external particles is mediated by a colored fermion and a colored scalar. We present compact analytic results for these two-loop corrections that are expressed in terms of Harmonic Polylogarithms. The expansion of these corrections in the low and high Higgs mass regimes, as well as the expression of the new Master Integrals which appear in the reduction of the two-loop amplitudes, are also provided. For the fermionic contribution, we provide an independent check of the…
Special Issue - Past, present and future challenges on customer experience: Digging knowledge across sectors
2019
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Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus.
2005
Human cytomegalovirus, a chief pathogen in immunocompromised people, can persist in a healthy immunocompetent host throughout life without being eliminated by the immune system. Here we show that pp65, the main tegument protein of human cytomegalovirus, inhibited natural killer cell cytotoxicity by an interaction with the activating receptor NKp30. This interaction was direct and specific, leading to dissociation of the linked CD3zeta from NKp30 and, consequently, to reduced killing. Thus, pp65 is a ligand for the NKp30 receptor and demonstrates a unique mechanism by which an intracellular viral protein causes general suppression of natural killer cell cytotoxicity by specific interaction w…
A novel epitope of N-CAM defines precursors of human adherent NK cells
2004
AbstractActivated, adherent natural killer (A-NK) cells represent a distinct subpopulation of interleukin (IL)-2-stimulated NK cells, which are selectively endowed with the increased expression of integrins and ability to adhere to solid surfaces, migrate into, infiltrate, and destroy cancerous tissues. The present study defines the phenotype and functions of precursors of A-NK (pre-A-NK) cells in humans. Peripheral blood pre-A-NK cells, in contrast to the rest of NK cells, express a novel epitope of CD56 neuronal cell adhesion molecule, termed ANK-1, and increased cell-surface levels of integrins. Pre-A-NK cells also express low levels of CD56 and CD161, and some express CD162 receptor, do…
Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules
2013
Abstract Tumor cell populations have been recently proposed to be composed of two compartments: tumor-initiating cells characterized by a slow and asymmetrical growth, and the “differentiated” cancer cells with a fast and symmetrical growth. Cancer stem cells or cancer-initiating cells (CICs) play a crucial role in tumor recurrence. The resistance of CICs to drugs and irradiation often allows them to survive traditional therapy. NK cells are potent cytotoxic lymphocytes that can recognize tumor cells. In this study, we have analyzed the NK cell recognition of tumor target cells derived from the two cancer cell compartments of colon adenocarcinoma lesions. Our data demonstrate that freshly p…
"Table 10" of "Measurements of Higgs boson properties in the diphoton decay channel with 36 fb$^{-1}$ of $pp$ collision data at $\sqrt{s} = 13$ TeV w…
2019
Measured differential cross section with associated uncertainties as a function of HT. Each systematic uncertainty sources is fully uncorrelated with the other sources and fully correlated across bins, except for the background modelling systematics for which an uncorrelated treatment across bins is more appropriate.
"Table 16" of "Measurements of Higgs boson properties in the diphoton decay channel with 36 fb$^{-1}$ of $pp$ collision data at $\sqrt{s} = 13$ TeV w…
2019
Measured differential cross section with associated uncertainties as a function of DPHI(2JET). Each systematic uncertainty sources is fully uncorrelated with the other sources and fully correlated across bins, except for the background modelling systematics for which an uncorrelated treatment across bins is more appropriate.
"Table 18" of "Measurements of Higgs boson properties in the diphoton decay channel with 36 fb$^{-1}$ of $pp$ collision data at $\sqrt{s} = 13$ TeV w…
2019
Measured differential cross section with associated uncertainties as a function of DPHI(2GAMMA,2JET). Each systematic uncertainty sources is fully uncorrelated with the other sources and fully correlated across bins, except for the background modelling systematics for which an uncorrelated treatment across bins is more appropriate.