Search results for "IgG"

showing 10 items of 1389 documents

Baculoviral display of functional scFv and synthetic IgG-binding domains.

2000

Viral vectors displaying specific ligand binding moities such as scFv fragments or intact antibodies hold promise for the development of targeted gene therapy vectors. In this report we describe baculoviral vectors displaying either functional scFv fragments or the synthetic Z/ZZ IgG binding domain derived from protein A. Display on the baculovirus surface was achieved via fusion of the scFv fragment or Z/ZZ domain to the N-terminus of gp64, the major envelope protein of the Autographa californica nuclear polyhedrosis virus, AcNPV. As examples of scFv fragments we have used a murine scFv specific for the hapten 2-phenyloxazolone and a human scFv specific for carcinoembryonic antigen. In pri…

Genetic enhancementvirusesRecombinant Fusion ProteinsBlotting WesternBiophysicschemical and pharmacologic phenomenaEnzyme-Linked Immunosorbent AssayVectors in gene therapySpodopteraBiochemistryViral vector03 medical and health sciencesMice0302 clinical medicineAntibody SpecificityPeptide LibraryAnimalsHumansMolecular BiologyImmunoglobulin FragmentsCells Cultured030304 developmental biology0303 health sciencesbiologyOxazoloneNuclear Polyhedrosis VirusCell Biologyrespiratory systembiology.organism_classificationMolecular biology3. Good healthCarcinoembryonic AntigenAutographa californicaIgG binding030220 oncology & carcinogenesisImmunoglobulin Gbiology.proteinBinding Sites AntibodyAntibodyHaptenBaculoviridaeHaptensViral Fusion ProteinsBiochemical and biophysical research communications
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2006

Understanding evolutionary processes that drive genome reduction requires determining the tempo (rate) and the mode (size and types of deletions) of gene losses. In this study, we analysed five endosymbiotic genome sequences of the gamma-proteobacteria (three different Buchnera aphidicola strains, Wigglesworthia glossinidia, Blochmannia floridanus) to test if gene loss could be driven by the selective importance of genes. We used a parsimony method to reconstruct a minimal ancestral genome of insect endosymbionts and quantified gene loss along the branches of the phylogenetic tree. To evaluate the selective or functional importance of genes, we used a parameter that measures the level of ad…

Genetics0303 health sciencesPhylogenetic treeBiologyWigglesworthia glossinidiabiology.organism_classificationGenome03 medical and health sciencesNegative selection0302 clinical medicineEvolutionary biologyPhylogeneticsCodon usage biasBuchneraGene030217 neurology & neurosurgeryEcology Evolution Behavior and Systematics030304 developmental biologyBMC Evolutionary Biology
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Limits on neutral Higgs boson production in the forward region in $pp$ collisions at $\sqrt{s} = 7$ TeV

2013

Limits on the cross-section times branching fraction for neutral Higgs bosons, produced in p p collisions at root s = 7 TeV, and decaying to two tau leptons with pseudorapidities between 2.0 and 4.5, are presented. The result is based on a dataset, corresponding to an integrated luminosity of 1.0 fb(-1), collected with the LHCb detector. Candidates are identified by reconstructing final states with two muons, a muon and an electron, a muon and a hadron, or an electron and a hadron. A model independent upper limit at the 95% confidence level is set on a neutral Higgs boson cross-section times branching fraction. It varies from 8.6 pb for a Higgs boson mass of 90 GeV to 0.7 pb for a Higgs bos…

GravitacióSEARCH; MSSM; LHCHadronStandard-model Higgs boson7. Clean energy01 natural sciencesHigh Energy Physics - ExperimentSettore FIS/04 - Fisica Nucleare e SubnucleareHigh Energy Physics - Experiment (hep-ex)[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Teoria quànticaNuclear ExperimentQCBosonPhysicsHiggs physicsQuantum field theoryHiggs bosonProduction (computer science)Física nuclearLHCHadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified leptons photons or other nonhadronic particlesParticle Physics - ExperimentGravitationParticle physicsTeoria quàntica de campsNuclear and High Energy PhysicsFOS: Physical sciencesStandard-model Higgs bosons; Supersymmetric Higgs bosons; Hadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified leptons photons or other nonhadronic particlesHadronsPartícules (Física nuclear)Standard ModelSEARCH0103 physical sciences010306 general physicsLarge Hadron Collider (France and Switzerland)Standard-model Higgs bosonsMuonHadron-Hadron Scattering010308 nuclear & particles physicsBranching fractionComputer Science::Information RetrievalHadron-Hadron Scattering; Higgs physicsHigh Energy Physics::PhenomenologyGran Col·lisionador d'HadronsHiggs physicSupersymmetric Higgs bosonSupersymmetric Higgs bosonsQuantum theoryHadron-Hadron Scattering; Higgs physics; Nuclear and High Energy PhysicsHigh Energy Physics::ExperimentMSSMLepton
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REMARKS ON THE HIGGS-PARTICLE PREDICTION IN THE STANDARD MODEL

2003

HIGGS ELECTROWEAK THEORYSettore FIS/04 - Fisica Nucleare E Subnucleare
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"Table 22" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13Te…

2020

Post-fit BDT distributions in the $Z\to \ell\ell$ CR for the $\tau_{\mathrm{lep}}\tau_{\mathrm{lep}}$ SF analysis channel. The size of the combined statistical, experimental, and theoretical uncertainties is given. The exact value of the $p_{\mathrm{T}}$ cut on the leptons depends on the trigger.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreHigh Energy Physics::PhenomenologyTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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"Table 20" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13Te…

2020

Post-fit BDT distributions in the top-quark CR for the $\tau_{\mathrm{lep}}\tau_{\mathrm{lep}}$ SF channel. The size of the combined statistical, experimental, and theoretical uncertainties is given. The exact value of the $p_{\mathrm{T}}$ cut on the leptons depends on the trigger.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreHigh Energy Physics::PhenomenologyTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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"Table 21" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13Te…

2020

Post-fit BDT distributions in the top-quark CR for the $\tau_{\mathrm{lep}}\tau_{\mathrm{lep}}$ DF channel. The size of the combined statistical, experimental, and theoretical uncertainties is given.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreHigh Energy Physics::PhenomenologyTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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"Table 3" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13TeV…

2020

Post-fit BDT distributions after the VBF event selection for the $\tau_{\mathrm{lep}}\tau_{\mathrm{had}}$ analysis channel. The VBF signal is shown for $\mu = 0.73$ and $\tilde d = -0.01$. ''Other bkg'' denotes all background contributions not listed explicitly in the legend. The size of the combined statistical, experimental, and theoretical uncertainties is given. The exact value of the $p_{\mathrm{T}}$ cut on the leading lepton depends on the trigger.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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"Table 2" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13TeV…

2020

Post-fit BDT distributions after the VBF event selection for the $\tau_{\mathrm{lep}}\tau_{\mathrm{lep}}$ DF analysis channel. The VBF signal is shown for $\mu = 0.73$ and $\tilde d = -0.01$. ''Other bkg'' denotes all background contributions not listed explicitly in the legend. The size of the combined statistical, experimental, and theoretical uncertainties is given.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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"Table 1" of "Test of CP invariance in vector-boson fusion production of the Higgs boson in the H → ττ channel in proton–proton collisions at s=13TeV…

2020

Post-fit BDT distributions after the VBF event selection for the $\tau_{\mathrm{lep}}\tau_{\mathrm{lep}}$ SF analysis channel. The VBF signal is shown for $\mu = 0.73$ and $\tilde d = -0.01$. ''Other bkg'' denotes all background contributions not listed explicitly in the legend. The size of the combined statistical, experimental, and theoretical uncertainties is given. The exact value of the $p_{\mathrm{T}}$ cut on the leptons depends on the trigger.

Higgs Production13000.0Proton-Proton ScatteringBDT ScoreTau-Tau DecayHigh Energy Physics::ExperimentP P -> H + X
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