Search results for "Ikääntymien"

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Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs

2009

We investigated whether long-term hormone replacement therapy (HRT) is associated with mobility and lower limb muscle performance and composition in postmenopausal women. Fifteen 54- to 62-yr-old monozygotic female twin pairs discordant for HRT were recruited from the Finnish Twin Cohort. Habitual (HWS) and maximal (MWS) walking speeds over 10 m, thigh muscle composition, lower body muscle power assessed as vertical jumping height, and maximal isometric hand grip and knee extension strengths were measured. Intrapair differences (IPD%) with 95% confidence intervals (CI) were calculated. The mean duration of HRT use was 6.9 ± 4.1 yr. MWS was on average 7% (0.9 to 13.1%, P = 0.019) and muscle…

SenescenceAgingmedicine.medical_specialtyvaihdevuodetPhysiologyMonozygotic twinWalkingIsometric ContractionPhysiology (medical)Internal medicineIkääntymienmedicineHumansMuscle Skeletalmuscle powersukupuolihormonitHand Strengthbusiness.industryEstrogen Replacement TherapySkeletal muscleEstrogenslihaksen voimantuottotehoTwins MonozygoticMiddle Agedmedicine.diseaseTwin studyTwin Studies as TopicMenopauseEndocrinologymedicine.anatomical_structureTransgender hormone therapyAgeingTwin Studies as TopicFemaleMenopauseTomography X-Ray ComputedbusinessMuscle ContractionlihasvoimaJournal of Applied Physiology
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