Search results for "Imperfect"

Cognitive representations of predicates and the use of past tenses in French: a developmental approach

1997

Two experiments examine how French 10-year-old children and adults relate past tenses to the semantic properties of predicate types in writing. Experiment 1 involved two tasks: graphically coding two predicate dimensions (durativity and resultativity), a task designed to assess cognitive representations of these predicates; and selecting past tenses in sentences which included previously evaluated verbs. Results show that (a) 10-year-olds and adults have comparable representations of durativity, but different ones for resultativity, (b) the adults associate process charac teristics and past tenses, but 10-year-olds do not. In Experiment 2, subjects only had to code graphically two dimensio…

Degradation of aromatic compounds through the β-ketoadipate pathway is required for pathogenicity of the tomato wilt pathogenFusarium oxysporumf. sp.…

2012

Plant roots react to pathogen attack by the activation of general and systemic resistance, including the lignification of cell walls and increased release of phenolic compounds in root exudate. Some fungi have the capacity to degrade lignin using ligninolytic extracellular peroxidases and laccases. Aromatic lignin breakdown products are further catabolized via the β-ketoadipate pathway. In this study, we investigated the role of 3-carboxy-cis,cis-muconate lactonizing enzyme (CMLE), an enzyme of the β-ketoadipate pathway, in the pathogenicity of Fusarium oxysporum f. sp. lycopersici towards its host, tomato. As expected, the cmle deletion mutant cannot catabolize phenolic compounds known to …

Analysis of piezoelectric active patches performances by boundary element techniques

2008

This paper presents the analysis of active piezoelectric patches for cracked structures by Boundary Element Method. A two dimensional boundary integral formulation based on the multidomain technique is used to model cracks and to assemble the multi-layered piezoelectric patches to the host damaged structures. The fracture mechanics behavior of the repaired structures is analyzed for both perfect and imperfect interface between patches and host beams. The imperfect interface, representing the adhesive between two different layers, is modeled by using a “Spring Model” that involves linear relationships between the interface tractions, in normal and tangential directions, and the respective di…

Hydroxylation of collagen type I: evidence that both lysyl and prolyl residues are overhydroxylated in osteogenesis imperfecta

1995

The composition of the collagens secreted into the media of fibroblast cultures of 39 patients with osteogenesis imperfecta (OI) was the same in controls and OI cultures. An abnormal migration pattern of collagens upon SDS-PAGE was evident in one third of the cultures investigated. Lysyl and prolyl hydroxylation of HPLC-purified alpha 1(I) chains was elevated in about 60% of cultures. The degree of hydroxylation was highest in the lethal forms. The extent of lysyl and prolyl hydroxylation showed a strong correlation (r = 0.74, P < 0.001). While high levels of hydroxylation are frequently observed in OI patients, a direct correlation between lysyl or prolyl hydroxylation and fracture rate or…

Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi Arabia

2022

BackgroundAlthough genetic diseases are rare, children with such conditions who get infected with COVID-19 tend to have a severe illness requiring hospitalization. Osteogenesis imperfecta (OI) is a rare genetic disorder of collagen resulting in fractures and skeletal deformities. Kyphoscoliosis, restrictive lung disease, and pneumonia worsen the prognosis of patients with OI. The use of bisphosphonate improves bone mineral density (BMD) and reduces fractures in OI. There is no literature describing the impact of COVID-19 in patients with OI.MethodologyA retrospective multi-center study was performed in three hospitals in Jeddah and Riyadh, Saudi Arabia, from March 1st, 2020, until August 31…

Pathological mandibular fracture after simple molar extraction in a patient with osteogenesis imperfecta treated with alendronate

2009

Osteogenesis imperfecta (OI), is a heterogeneous group of inherited disorders of connective tissue characterized by bone fragility. Patients with this disease frequently suffer fractures, over 80% of the extremities due to the more intensive mechanical load. Fractures of the facial bones occur very infrequently. Several studies have proved that bisphosphonate therapy may be effective in reducing fracture risk in OI patients. We report here an unusual case of pathological mandibular fracture following simple molar extraction in an adult patient with OI type I and oral alendronic acid treatment. Extraction was atraumatical and without bone removal . Fracture was treated by internal fixation b…

Sonographic diagnosis of lethal osteogenesis imperfecta in the second trimester: case report and review.

1986

Trade is not necessary for agglomeration to arise

2003

We develop a spatial general equilibrium model in which the absence of trade is an endogenous outcome and we show that trade is not a necessarycondition for agglomeration to arise. More precisely, extending the modeldeveloped by Ottaviano et al. [13], we show that equilibria without tradediffer significantly from those obtained in the presence of trade. Somewhatsurprisingly, equilibrium structures without trade are richer than those withtrade, since partial agglomeration becomes a feasible outcome. Equilibrianow depend on the ratio of mobile to immobile factors and an increase in thatratio triggers a process of spatial agglomeration.

Morphological and molecular taxonomy ofPythium longisporangiumsp. nov. isolated from the Burgundian region of France

2005

During the course of an investigation on the Pythiaceous oomycetes occurring in the Burgundian vineyards, some species of Pythium possessing mainly hypogynous antheridia were found. These had been classified as oomycetes belonging to the ‘‘Pythium rostratum’’ group for a long time. Three of these isolates, having similar structures and growth, are very closely related to a recently described species, Pythium bifurcatum Paul. A close look at these, however, underlines some fundamental differences with the latter. Not all of them produce zoospores but have very large sporangia. The type specimen is F-1200 (B 76a) which is a medium-slow growing saprophyte. The sequence of the ITS region of the…

A Bayesian approach for predictive maintenance policy with imperfect monitoring

2009

In the traditional preventive maintenance policy, the periodic maintenance activities are scheduled on the basis of the a-priori information about the failure behaviour of the population which the component belongs to, by assuming a probability distribution function and by estimating the involved statistical parameters. On the contrary, with the predictive approach, the maintenance activity is scheduled on the basis of the real degradation level of the component. So, it is possible to reduce the failure probability and, at the same time, to use the component for almost all its useful life. For this reason, the predictive maintenance policy makes possible the reduction of the maintenance cos…