Search results for "Incidence"
showing 10 items of 2270 documents
Urban green spaces and childhood leukemia incidence: A population-based case-control study in Madrid.
2021
Abstract Background Childhood leukemia is the most common childhood cancer. To date, few risk factors related to predisposition have been identified; therefore, new hypotheses should be considered. Objective To explore the possible relationship of residential proximity to urban green spaces on childhood leukemia. Methods We conducted a population-based case control study in the metropolitan area of Madrid from 2000 to 2015. It included 383 incident cases and 1935 controls, individually matched by birth year, sex and area of residence. Using the geographical coordinates of the participants’ home residences, we built a proxy for exposure with four distances (250 m, 500 m, 750 m and 1 km) to u…
Epidemiology of Mantle Cell Lymphoma: A Population-Based Study in France
2011
Abstract Abstract 5222 Introduction: Mantle cell lymphoma (MCL) is an aggressive and rare B-cell lymphoma entity representing around 5–8% of non-Hodgkin's lymphomas in adults. To our knowledge no data is available on the epidemiology of MCL in France. We aimed to describe incidence, survival and main clinical characteristics of MCL in a French population. Methods: Patients diagnosed with MCL were identified in three administrative areas covered by an haematological malignancies registry: the Côte d'Or (from 1988 to 2008), the Basse-Normandie (from 1997 to 2006) and the Gironde (from 2002 to 2006). Main clinical features and management characteristics were collected. World age-standardised …
219 Incidence Testing of Hunter Syndrome in A Population at Risk - First Results of A Binational Screening Programme
2012
Background Hunter syndrome (Mucopolysaccharidosis type II; X-linked inheritance; prevalence rate in Europe approximately 1:77000 male newborns) is a rare, progressive, multisystemic disease, caused by deficiency of the lysosomal enzyme Iduronate-2-sulfatase. Due to the very heterogeneous phenotype Hunter syndrome is often not diagnosed before pre-school age. This is unfortunate, because patients would significantly benefit from the earliest possible start of treatment containing enzyme replacement therapy. Early screening methods are possible, but due to the rarity of this disease they are too expensive to be performed in all newborns. An at-risk patient population screening provides opport…
Epidemiology of childhood cancer
2010
The present contribution reports childhood cancer incidence and survival rates as well as time trends and geographical variation. The report is based on the databases of population-based cancer registries which joined forces in cooperative projects such as Automated Childhood Cancer Information System (ACCIS) and EUROCARE. According to these data, which refer to the International Classification of Childhood Cancer, leukemias, at 34%, brain tumors, at 23%, and lymphomas, at 12%, represent the largest diagnostic groups among the under 15-year-olds. The most frequent single diagnoses are: acute lymphoblastic leukemia, astrocytoma, neuroblastoma, non-Hodgkin lymphoma, and nephroblastoma. There …
Incidence, severity and orthodontic treatment difficulty index of impacted canines in Saudi population
2018
Background The objective of this study was to assess the incidence, severity and orthodontic treatment difficulty of impacted maxillary canines in Saudi population. Material and methods This retrospective study included an investigation of panoramic radiographs for patients attended College of Dentistry, Jazan University, Saudi Arabia. The incidence of canine impaction and orthodontic treatment difficulty index of maxillary canine impaction was assessed based on; (1) patient age, (2) vertical position, (3) buccolingual position, (4) horizontal position, (5) incisors alignment, (6) canine space, (7) midline coincidence, (8) rotation of impacted tooth. Statistical analyses were calculated by …
Symptoms of depersonalization/derealization are independent risk factors for the development or persistence of psychological distress in the general …
2016
Abstract Background Symptoms of depersonalization (DP) and derealization (DR) have a high prevalence in patient and community samples. Previous studies suggested that DP/DR symptoms might represent a marker of disease severity and poor prognosis. However, population-based studies investigating the impact of DP/DR symptoms on the course of depression and anxiety are sparse. Therefore, we aimed to analyze whether symptoms of DP/DR are longitudinally associated with the persistence or incidence of elevated symptoms of depression/anxiety. Methods We analyzed observational data from a sample of 13.182 participants of the Gutenberg Health Study. The outcomes were elevated symptoms of depression/a…
Case Control Study on Childhood Leukemia in Lower Saxony, Germany
1996
In two municipalities in Lower Saxony statistically valid clusters were observed, which attracted great public interest. Committees were set up to initiate a large variety of on-the-spot-investigations. Finally, it was decided to conduct a case control study throughout Lower Saxony to explore potential risk factors which might explain the observed clusters. A limited number of already established and currently discussed hypotheses was chosen for investigation. The study was based on patients registrated at the German Children's Cancer Registry (GCCR). For each child with leukemia diseased between 1988 and 1993 two population-based controls (local and state controls) and one tumour control w…
SP1-5 Endocrine, nutritional and metabolic diseases as associated causes of death in older women in Rio de Janeiro, Brazil
2011
Introduction Changes in lifestyle contributed to an increased incidence and mortality from endocrine, nutritional and metabolic diseases in developing countries. The aim of this study was to evaluate the burden of these diseases as a cause of death in older women in a Brazilian city. Methods All deaths of women aged 70 years or older, occurring in Rio de Janeiro, between 2003 and 2006, were identified in the Mortality Information System, a population-based nationwide registry. Death certificates with an ICD 10 Chapter IV code (E00-E90) were selected. When the code corresponded to the underlying cause, its subgroup was determined (endocrine, nutritional or metabolic diseases) and the associa…
Visual defects in subjects with Down’s syndrome
1995
Because the incidence of other visual defects is much higher in cases of Down’s syndrome than in individuals with other forms of retardation (Gardiner, 1967; Aitchison et al., 1990), we tested the color vision of a population of Down’s syndrome patients, using Ishihara plates and the Davico anomaloscope. The Down’s syndrome group had a significantly higher proportion of color deficiencies than either normal controls or a matched mentally retarded population. Refractive errors were corrected with static retinoscopy, and spatial contrast sensitivity was measured with the Vistech test.
CT and MR Imaging of Brain Tumors
1989
Our clinical population numbered 8516 patients with primary and metastatic brain tumors who underwent evaluation by computed tomography at the neurosurgical and neuroradiologic departments of the Berlin, Mainz, and Munich centers from 1975 to 1986 and at the Neurosurgical Department of Augsburg Central Hospital from 1983 to 1986. Table 5 lists all the tumors having an incidence greater than 1% in the total population; 98% of the lesions were confirmed histologically (open surgery, stereotactic biopsy, autopsy). “Rare” intracranial tumors having an incidence no greater than 1% are listed in Table 6. The frequencies of the individual tumor types correlate well with the statistical data report…