Search results for "Indole"

showing 10 items of 570 documents

The effect of indole-3-acetic-acid on the photosynthetic apparatus of Sinapis alba

1980

The influence of indole-3-acetic-acid (IAA) during the development of primary leaves of Sinapis alba was studied. IAA treatment (4 ppm ≈ 22.8 μM) caused a decrease of dry weight, soluble reducing sugars, soluble protein, chlorophylls, carotenoids and cytochrome f; it also caused a lower ratio of protein to chlorophyll, a lower ratio of chlorophyll a to chlorophyll b and a higher ratio of chlorophyll per cytochrome f. Furthermore, IAA treatment induced a significantly lower rate of CO2 fixation and a depressed nitrite reductase activity. Similar effects could also be observed in adaptation reactions brought about by red light and low-light (or shade) conditions.

Cytochrome fChlorophyll bChlorophyll abiologySinapisfood and beveragesPlant physiologyCell BiologyPlant ScienceGeneral MedicinePhotosynthesisbiology.organism_classificationBiochemistrychemistry.chemical_compoundchemistryChlorophyllBotanyFood scienceIndole-3-acetic acidPhotosynthesis Research
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Vibrio ponticus sp. nov., a neighbour of V fluvialis-V. furnissii clade, isolated from gilthead sea bream, mussels and seawater.

2004

A new Vibrio species, Vibrio ponticus, is proposed to accommodate four marine bacteria isolated from sea water, mussels and diseased sea bream (Sparus aurata), at the Mediterranean coast of Spain. Strains are Gram negative, slightly halophilic bacteria that require Na+ ion for growth, oxidase and catalase positive, negative for arginine dihydrolase and ornithine decarboxylase but positive for lysine decarboxylase and indole, and utilize beta-hydroxybutyrate as a sole carbon source. Phylogenetic analysis locate these marine bacteria in the vicinity of the V. fluvialis-V. furnissii clade, sharing with these two species 16S rDNA sequence similarities slightly above 97% (97.1 and 97.3%, respect…

DNA BacterialIndolesCarboxy-LyasesHydrolasesMolecular Sequence DataBiologyOrnithine DecarboxylaseApplied Microbiology and BiotechnologyMicrobiologyDNA RibosomalMicrobiologyMarine bacteriophageVibrionaceaeVibrio InfectionsRNA Ribosomal 16SSequence Homology Nucleic AcidMediterranean SeaAnimalsSeawaterRibosomal DNAEcology Evolution Behavior and SystematicsPhylogenyVibrioLysine decarboxylase3-Hydroxybutyric AcidFatty AcidsNucleic Acid HybridizationSequence Analysis DNA16S ribosomal RNAbiology.organism_classificationCatalaseVibrioSea BreamBivalviaSpainVibrio InfectionsPhenazinesGentian VioletOxidoreductasesBacteriaSystematic and applied microbiology
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Aeromonas encheleia sp. nov., isolated from European Eels

1995

Four strains isolated from European eels in Valencia, Spain, were found to constitute a DNA relatedness group which is 0 to 50% related to the 13 species and DNA group 11 of the genus Aeromonas. Phenotypically, these strains have all of the properties that define the genus Aeromonas. However, they differ from the previously described Aeromonas species by three or more properties. The strains are positive for motility, growth at 37 degrees C, indole production, and arginine dihydrolase activity. They exhibit negative reactions in tests for growth at 42 degrees C and in thiosulfate-citrate-bile salts-sucrose medium (Oxoid), Simmons citrate tests, and tests for lysine and ornithine decarboxyla…

DNA BacterialIndolesImmunologyPenicillinsMicrobiologyMicrobiologychemistry.chemical_compoundNucleic acid thermodynamicsSalicinCell MovementVibrionaceaeSequence Homology Nucleic AcidAnimalsAeromonas encheleiaAmino AcidsLactoseBase CompositionSulfonamidesbiologyArbutinNucleic Acid HybridizationDrug Resistance MicrobialAnguillabiology.organism_classificationPhenotypechemistrySpainCarbohydrate MetabolismAeromonasEnergy sourceBacteria
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Vibrio aestivus sp. nov. and Vibrio quintilis sp. nov., related to Marisflavi and Gazogenes clades, respectively

2012

Abstract Two new Vibrio species, Vibrio aestivus and Vibrio quintilis , are described after a polyphasic characterization of strains M22 T , M61 and M62 T , isolated from seawater collected off a beach on the East coast of Spain (Valencia). All three strains are Gram negative, mesophilic, slightly halophilic, fermentative rods. V. aestivus (M22 T  = CECT 7558 T  = CAIM 1861 T  = KCTC 23860 T and M61 = CECT 7559 = CAIM 1862 = KCTC 23861) is oxidase positive, reduces nitrates to nitrites, is negative for Voges Proskauer, arginine dihydrolase and indole and non hydrolytic on most substrates tested. The 16S rRNA gene sequences of M22 T and M61 are most similar to Vibrio marisflavi (97.1–97.2%) …

DNA Bacterialfood.ingredientMolecular Sequence DataBiologyDNA RibosomalApplied Microbiology and BiotechnologyMicrobiologyMicrobiologyfoodRNA Ribosomal 16SCluster AnalysisAgarSeawaterPhylogenyEcology Evolution Behavior and SystematicsVibrioIndole testOxidase testPhylogenetic treeStrain (chemistry)TemperatureSequence Analysis DNA16S ribosomal RNAHalophileBacterial Typing TechniquesMetabolismVoges–Proskauer testSpainSystematic and Applied Microbiology
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Acetyltransfer in natural product biosynthesis--functional cloning and molecular analysis of vinorine synthase.

2004

Vinorine synthase (EC 2.3.1.160) catalyses the acetyl-CoA- or CoA-dependent reversible formation of the alkaloids vinorine (or 11-methoxy-vinorine) and 16-epi-vellosimine (or gardneral). The forward reaction leads to vinorine, which is a direct biosynthetic precursor along the complex pathway to the monoterpenoid indole alkaloid ajmaline, an antiarrhythmic drug from the Indian medicinal plant Rauvolfia serpentina. Based on partial peptide sequences a cDNA clone was isolated and functionally expressed in Escherichia coli. The Km values of the native enzyme for gardneral and acetyl-CoA were determined to be 7.5 and 57 microM. The amino acid sequence of vinorine synthase has highest level of i…

DNA ComplementaryStereochemistrySequence analysisClinical BiochemistryMolecular Sequence DataPharmaceutical ScienceSequence alignmentBiochemistryRauwolfiaIndole AlkaloidsSubstrate Specificitychemistry.chemical_compoundBiosynthesisAcetyltransferasesSequence Analysis ProteinDrug DiscoveryConsensus sequenceAmino Acid SequenceCloning MolecularMolecular BiologyPeptide sequencechemistry.chemical_classificationATP synthasebiologyChemistryOrganic ChemistryAcetylationAmino acidBiochemistryAcetyltransferasebiology.proteinMutagenesis Site-DirectedMolecular MedicineSequence AlignmentBioorganicmedicinal chemistry
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LA DOPPIA CITAZIONE DEL FR. 964 DI EURIPIDE NEL DE INDOLENTIA DI GALENO

2013

The purpose of this study is to demonstrate that the second quotation of the Euripidean fr. 964 N 2 in the De indolentia, a Galenic treatise recently saved from oblivion thanks to Antoine Pietrobelli, is in fact an interpolation due to the enterprise of a scribe. The argumentation is based on words coming immediately before and after the presumed quotation.

De indolentia Galien fr. 964 N 2 di Euripide ἀλυπίας.
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Deoxysarpagine Hydroxylase — A Novel Enzyme Closing a Short Side Pathway of Alkaloid Biosynthesis in Rauvolfia

2002

Microsomal preparations from cell suspension cultures of the Indian plant Rauvolfia serpentina catalyze the hydroxylation of deoxysarpagine under formation of sarpagine. The newly discovered enzyme is dependent on NADPH and oxygen. It can be inhibited by typical cytochrome P450 inhibitors such as cytochrome c, ketoconazole, metyrapone, tetcyclacis and carbon monoxide. The CO-effect is reversible with light (450 nm). The data indicate that deoxysarpagine hydroxylase is a novel cytochrome P450-dependent monooxygenase. A pH optimum of 8.0 and a temperature optimum of 35 degrees C were determined. K(m) values were 25 microM for NADPH and 7.4 microM for deoxysarpagine. Deoxysarpagine hydroxylase…

Deoxysarpagine hydroxylase activityLightCytochromeStereochemistryClinical BiochemistryPharmaceutical ScienceBiochemistryRauwolfiaIndole AlkaloidsHydroxylationchemistry.chemical_compoundCytochrome P-450 Enzyme SystemRauvolfia serpentinaDrug DiscoveryMolecular BiologyPlant Proteinschemistry.chemical_classificationCarbon MonoxidebiologyChemistryDeoxysarpagine hydroxylaseCytochrome cOrganic ChemistryTemperatureHydrogen-Ion ConcentrationMonooxygenasebiology.organism_classificationSecologanin Tryptamine AlkaloidsKineticsEnzymeBiochemistrybiology.proteinMolecular MedicineAryl Hydrocarbon HydroxylasesNADPBioorganic & Medicinal Chemistry
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Dopamine Autoreceptor Agonists in the Treatment of Schizophrenia and Major Depression*

1992

Dopamine autoreceptor agonists reduce the firing rate, synthesis, and release of dopamine in dopaminergic neurons by means of a negative feedback mechanism via stimulation of autoreceptors. Moreover, dopamine autoreceptor agonists are able to stimulate supersensitive but not normosensitive postsynaptic receptors. For dopamine autoreceptor agonists, therapeutic effects by readjustment of excessive or deficient dopaminergic function have been postulated for positive and negative schizophrenic symptomatology as well as for subtypes of depressive disorders. Investigations on the therapeutic effects of autoreceptor-nonselective dopamine agonists in schizophrenia or depression have yielded incons…

Depressive Disordermedicine.medical_specialtyDopamine AgentsDopaminergicGeneral MedicineDopamine agonistTalipexolePsychiatry and Mental healthchemistry.chemical_compoundEndocrinologyRoxindolechemistryDopamine receptorDopamine receptor D3DopamineInternal medicineSchizophreniamedicineAutoreceptorAnimalsHumansPharmacology (medical)PsychiatryPsychologymedicine.drugPharmacopsychiatry
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Development and Validation of a Reversed-Phase Liquid Chromatography Method for the Simultaneous Determination of Indole-3-Acetic Acid, Indole-3-Pyru…

2011

A simple, sensitive, precise, and specific reverse HPLC method was developed and validated for the determination of plant hormones in barley (Hordeum vulgareL.). The method includes extraction in aqueous organic solvent followed by solid-phase extraction, sample evaporation, and reversed-phase HPLC analysis in a general purpose UV-visible (abscisic acid (ABA)) and fluorescence detection (indole-3-acetic acid (IAA) and indole-3-pyruvic acid (IPA)), high-performance liquid chromatography system. The separation was carried out on Zorbax Eclipse XDB C8 column (150 × 4.6 mm I.D) with a mobile phase composed of methanol and 1% acetic acid (60 : 40 v/v) in isocratic mode at a flow rate of 1 ml min…

Detection limitChromatographylcsh:QD71-142Article SubjectGeneral Chemical EngineeringExtraction (chemistry)lcsh:Analytical chemistryfood and beveragesReversed-phase chromatographyComputer Science ApplicationsAnalytical Chemistrychemistry.chemical_compoundAcetic acidchemistryHordeum vulgareMethanolIndole-3-acetic acidInstrumentationAbscisic acidResearch ArticleJournal of Analytical Methods in Chemistry
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ChemInform Abstract: Diels-Alder Reactions of in situ Generated N-Benzoylindolo-2,3- quinodimethane with Carbodienophiles.

2010

The indolo-2,3-quinodimethane (5), generated from 2,3-bis(bromomethyl)indole (4), was trapped with unsymmetrical carbodienophiles or N, N′-p-phenylenedimaleimide to furnish the 1,2,3,4-tetrahydrocarbazoles (6–9). [4 + 2]-Cycloaddition of 5 with tetracyanoethylene gave rise to the tetracyanocarbazole (10) and a subsequent product 11a or 11b. The Diels-Alder reaction of 5 with divinyl sulfone was regiospecific within the detection limits of HPLC analysis. Similarly, the reaction of 5 with N, N′-p-phenylenedimaleimide yielded solely the stereoisomer 9.

Detection limitIndole testIn situHplc analysischemistry.chemical_compoundchemistryDiels alderGeneral MedicineTetracyanoethyleneMedicinal chemistryDivinyl sulfoneChemInform
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