Search results for "Injection"

showing 10 items of 920 documents

Neurochemistry of identified motoneurons of the tensor tympani muscle in rat middle ear

2008

The objective of the present study was to identify efferent and afferent transmitters of motoneurons of the tensor tympani muscle (MoTTM) to gain more insight into the neuronal regulation of the muscle. To identify MoTTM, we injected the fluorescent neuronal tracer Fluoro-Gold (FG) into the muscle after preparation of the middle ear in adult rats. Upon terminal uptake and retrograde neuronal transport, we observed FG in neurons located lateral and ventrolateral to the motor trigeminal nucleus ipsilateral to the injection site. Immunohistochemical studies of these motoneurons showed that apparently all contained choline acetyltransferase, demonstrating their motoneuronal character. Different…

medicine.medical_specialtyStilbamidinesEar MiddleNeuropeptideSubstance PCalcitonin gene-related peptideInjections IntramuscularTensor tympani muscleCholine O-AcetyltransferaseRats Sprague-Dawleychemistry.chemical_compoundInternal medicinemedicineAnimalsNeuronal transportFluorescent DyesMotor NeuronsStaining and LabelingTyrosine hydroxylaseChemistryNeuropeptidesNeurochemistryNeuropeptide Y receptorImmunohistochemistryCholine acetyltransferaseSensory SystemsRatsEndocrinologynervous systemFemaleTensor TympaniHearing Research
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Oxygen consumption is a quality marker for human oocyte competence conditioned by ovarian stimulation regimens.

2011

Objective To evaluate the effect of different ovarian stimulation protocols on oocyte respiration and to investigate the relationship between oocyte oxygen consumption and reproductive outcome. Design Prospective observational cohort study. Setting Infertility clinic in a university hospital. Patient(s) A total of 349 oocytes from 56 IVF treatment cycles in our oocyte donation program. Intervention(s) None. Main Outcome Measure(s) Average oocyte oxygen consumption rate in fmol/s. We correlated oxygen consumption values with ovarian stimulation features, fertilization, embryo quality on days 2 and 3, and implantation. Result(s) Differences in the measured oxygen consumption rates were found …

medicine.medical_specialtyStimulationBiologyAndrologyHuman fertilizationOxygen ConsumptionOvulation InductionPregnancyInternal medicineRespirationmedicineHumansEmbryo ImplantationSperm Injections IntracytoplasmicOocyte DonationObstetrics and GynecologyEmbryoOdds ratioOocyteEmbryo TransferConfidence intervalOxygenEndocrinologymedicine.anatomical_structureBlastocystReproductive MedicineFertilizationOocytesFemaleInfertility FemaleEmbryo qualityBiomarkersFertility and sterility
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Intracardiac Cardioversion for Ablation of the Atrioventricular Conduction System in Patients with Drug Resistant Atrial Flutter

1983

The technique of intracardiac cardioversion for the ablation of the atrioventricular conduction system was used in three male patients (65, 53 and 57 years of age) with atrial flutter unresponsive to medical management. In the first patient a DC current of 80 J was applied while the other patients required 300 and 400 J respectively. In the first patient a transient third degree AVblock was induced enabling the ventricular rate to be easily controlled with drugs. This patient died 5 months later of resistant congestive heart failure. Autopsy revealed no gross evidence of myocardial damage in the tricuspid valve area or in the interventricular septum. In the other two patients a permanent th…

medicine.medical_specialtySupraventricular arrhythmiabusiness.industrymedicine.medical_treatmentAutopsyAblationCardioversionmedicine.diseaseIntracardiac injectionmedicine.anatomical_structureInternal medicineHeart failurecardiovascular systemCardiologyMedicinecardiovascular diseasesInterventricular septumbusinessAtrial flutter
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Efficacy of botulinum toxin in the treatment of bruxism : systematic review

2019

Background Currently it has been shown that botulinum toxin is effective for a wide variety of medical conditions, and can be applied for therapeutic purposes as cosmetic. In recent years, there has been a growing trend in the use of this drug substance to control the muscular overactivity of bruxism. The objective of this study was the use of botulinum toxin type A (BTX-A) than traditional methods, by conducting a systematic review of randomized clinical trials (RCTs) published in the health sciences literature. Material and Methods An electronic search was made in the databases of the PubMed, Cochrane Library and Scopus data between March and October 2017, ECA, which will analyze the effe…

medicine.medical_specialtyToxina botulínicaMEDLINEReviewCochrane LibraryPlaceboInjections Intramuscularlaw.inventionMasseter muscleOcclusal Splints03 medical and health sciences0302 clinical medicineRandomized controlled triallawBotulinum toxinmedicineHumansBotulinum Toxins Type AGeneral DentistryOral Medicine and Pathologybusiness.industryMasseter MuscleBruxisme030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Botulinum toxinstomatognathic diseasesOtorhinolaryngologyNeuromuscular AgentsUNESCO::CIENCIAS MÉDICASPhysical therapySurgeryBruxismbusinessBiomedical sciencesmedicine.drug
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Update on the principles and novel local and systemic therapies for the treatment of non-infectious uveitis.

2012

Ocular inflammatory disorders constitute a sight-threatening group of diseases that might be managed according to their severity. Their treatment guidelines experience constant changes with new agents that improve the results obtained with former drugs. Nowadays we can make use of a five step protocol in which topical, periocular and systemic corticosteroids remain as the main therapy for non-infectious uveitis. In addition, immunosuppresive drugs can be added in order to enhance the anti-inflammatory effects and to play the role of corticosteroid-sparing agents. These can be organized in four other steps: cyclosporine and methotrexate in a second one; azathioprine, mycophenolate and tacrol…

medicine.medical_specialtyTreatment protocolCyclophosphamideAdministration TopicalImmunologyAnti-Inflammatory AgentsAzathioprineUveitisInfectious uveitisAdrenal Cortex HormonesmedicineImmunology and AllergyAnimalsHumansIntensive care medicinePharmacologyChlorambucilbusiness.industryTumor Necrosis Factor-alphaGeneral Medicinemedicine.diseaseTacrolimusSurgeryInjections IntravenousPractice Guidelines as TopicMethotrexateImmunotherapybusinessUveitisAlgorithmsImmunosuppressive Agentsmedicine.drugInflammationallergy drug targets
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Intravitreal dexamethasone implant for cystoid macular edema and inflammation after scleral buckling

2015

Purpose Cystoid macular edema may occur following scleral buckling and therefore deteriorate the visual outcome. Inflammation may be the major causative factor in the development of postoperative cystoid macular edema. This case demonstrates the effectiveness of a dexamethasone implant as a treatment after the onset of choroidal inflammation and cystoid macular edema 6 months following scleral buckling and having visual acuity restored. Methods A 59-year-old phakic woman treated with scleral buckling for macula-off retinal detachment presented 2 months after surgery with cystoid macular edema with choroidal inflammation. Optical coherence tomography and fluorescein angiography were performe…

medicine.medical_specialtyTriamcinolone acetonideVisual acuityChoroiditisgenetic structuresVisual AcuityTriamcinolone AcetonideDrug ImplantDexamethasoneMacular EdemaChoroiditiPostoperative ComplicationsGlucocorticoidOptical coherence tomographyOphthalmologyChoroidal inflammationMedicineHumansFluorescein AngiographyMacular edemaGlucocorticoidsDexamethasoneDrug Implantsmedicine.diagnostic_testbusiness.industryIntravitreal InjectionRetinal DetachmentRetinal detachmentGeneral MedicineIntravitreal dexamethasone implantMiddle Agedmedicine.diseaseFluorescein angiographyeye diseasesOphthalmologyScleral BucklingIntravitreal InjectionsFemalesense organsImplantPostoperative Complicationmedicine.symptombusinessCystoid macular edemaTomography Optical Coherencemedicine.drugHuman
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Is Kelami's Method Still Useful in the Smartphone Era? The Virtual 3-Dimensional Reconstruction of Penile Curvature in Patients With Peyronie's Disea…

2021

Abstract Background Peyronie's disease is an idiopathic fibrotic disease affecting the penile tunica albuginea. Among other resulting deformities, the more common penile curvature should be assessed preferentially with in-office goniometric estimation after pharmacologically induced erection, although clearly invasive and uncomfortable. Aim In the present pilot study, we investigated the usefulness for the patient and the surgeon of a 3-dimensional (3D) reconstruction of the penile curvature obtained through photogrammetry software in clinical evaluation and surgical planning. Methods Enrolled patients received alprostadil 10 μg by intracavernous injection. Then, the medical personnel took …

medicine.medical_specialtyUrologyEndocrinology Diabetes and MetabolismPreoperative counseling030232 urology & nephrologyIntracavernous injectionSurgical planning03 medical and health sciences0302 clinical medicineEndocrinologymedicineIn patientReconstructive Surgical Procedures030219 obstetrics & reproductive medicinePeyronie's DiseaseGroinbusiness.industryGeneral surgerymedicine.diseasePsychiatry and Mental healthmedicine.anatomical_structureReproductive MedicineThree-Dimensional ImageComputer-Assisted DiagnosisPenile curvaturePeyronie's diseasebusinessPenis
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Observational outcomes in proliferative diabetic retinopathy patients following treatment with ranibizumab, panretinal laser photocoagulation or comb…

2021

Purpose Ranibizumab monotherapy showed stronger effects on area of retinal neovascularization (NV) reduction while offering better visual acuity (VA) results than panretinal laser photocoagulation (PRP) monotherapy during the first 12 months of the PRIDE study. The second year of PRIDE was an observational, non-interventional follow-up, performed to evaluate long-term anatomical and functional outcomes in proliferative diabetic retinopathy (PDR) patients under real-life conditions, prior to the approval of ranibizumab for PDR. Methods Seventy-three PDR patients (28 from the ranibizumab group; 20 from the PRP group; 25 from the combination group) were included in the observational follow-up …

medicine.medical_specialtyVisual acuityCombination therapyVisual AcuityAngiogenesis InhibitorsLight CoagulationPanretinal laser photocoagulation03 medical and health sciencesRetinal neovascularization0302 clinical medicineOphthalmologyRanibizumabMedicineHumansDiabetic Retinopathybusiness.industryGeneral MedicineDiabetic retinopathymedicine.diseaseCombined Modality TherapyDiscontinuationOphthalmologyIntravitreal Injections030221 ophthalmology & optometryObservational studyRanibizumabmedicine.symptombusiness030217 neurology & neurosurgerymedicine.drugFollow-Up StudiesActa ophthalmologicaReferences
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Urgent Vitrectomy with Vancomycin Infusion, Silicone Oil Endotamponade, and General Antibiotic Treatment in Multiple Cases of Endophthalmitis from a …

2021

The aim of this study was to report on the anatomical and functional results of surgical management of seven cases of endophthalmitis related to a single day of intravitreal aflibercept injections. Patients with signs of endophthalmitis who underwent aflibercept injections (seven eyes) performed on the same day were retrospectively evaluated. The data of visual acuity and optical coherence tomography (OCT) within nine months of the follow-up and the treatment and results of microbiological cultures are reported. Four of the total seven cases had a positive bacterial culture outcome (Streptococcus mitis). All patients underwent vitrectomy combined with phacoemulsification when the eyes were …

medicine.medical_specialtyVisual acuitygenetic structuresmedicine.medical_treatmentlcsh:MedicineVitrectomyBacterial endophthalmitiArticle03 medical and health sciences0302 clinical medicineEndophthalmitisOphthalmologymedicinepost-injection endophthalmitis030212 general & internal medicineAfliberceptendophthalmitis treatmentbusiness.industrylcsh:Rbacterial endophthalmitisGeneral MedicinePhacoemulsificationMacular degenerationmedicine.disease<i>Streptococcus mitis/oralis</i>eye diseasesStreptococcus mitis/oralis030221 ophthalmology & optometryVancomycinTamponadeBacterial endophthalmitis; En-dophthalmitis treatment; Post-injection endophthalmitis; Streptococcus mitis/oralissense organsmedicine.symptomPost-injection endophthalmitiEn-dophthalmitis treatmentbusinessmedicine.drugJournal of Clinical Medicine
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The fate of implant after endoscopic injection of dextranomer/hyaluronic acid in vesicoureteral reflux: time to partial reabsorption and stabilization

2020

Summary Background/introduction Vesicoureteral reflux (VUR) potentially leads to renal damage, scarring, and eventually end-stage renal disease. Endoscopic treatment is well tolerated in children, it has reduced costs, and it effectively prevents urinary tract infections (UTIs), while avoiding long term antibiotics use. Objective With the aim to investigate the time needed to reach the stabilization of the dextranomer/hyaluronic acid (Dx/HA) implants and to identify cut-off heights to ensure the success of the procedure, the authors analyzed ultrasonographic (US) intra-operative appearance of the mounds following endoscopic treatment for VUR and repeated the measurements during serial posto…

medicine.medical_specialtyVoiding cystourethrogramUrologyUrinary system030232 urology & nephrologyVesicoureteral reflux03 medical and health sciences0302 clinical medicine030225 pediatricsmedicineHumansHyaluronic AcidAntibiotic prophylaxisChildMound heightRetrospective StudiesVesico-Ureteral Refluxmedicine.diagnostic_testReabsorptionbusiness.industryVesicoureteral refluxRefluxInfantDextransmedicine.diseaseSurgeryTreatment OutcomeReabsorptionSub-ureteral injectionPediatrics Perinatology and Child HealthDextranomerImplantbusinessmedicine.drugJournal of Pediatric Urology
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