Search results for "Inorganic chemist"

showing 10 items of 7340 documents

Synthesis and characterization of ferrocene-based Schiff base and ferrocenecarboxaldehyde oxime and their adsorptive removal of methyl blue from aque…

2018

Abstract The ferrocene-based Schiff base 3 was synthetized by reaction of ferrocenecarboxaldehyde 1 with 4-aminoantipyrine 2. However, the reaction of 1 with hydroxylamine affords ferrocenecarboxaldehyde oxime 4. Compounds 3 and 4 were fully characterized by IR, 1H, 13C and DEPT-135 NMR spectroscopy, elemental analyses and also by single crystal X-ray diffraction. Compounds 3 and 4 were used to remove anionic methyl blue dye from wastewater. The results established that both compounds have high adsorption capacity towards methyl blue. Langmuir adsorption capacity of compound 4 (464 mmol/g) is much higher than that of compound 3 (193 mmol/g) at 25 °C. The kinetics data was fitted well pseudo…

methyl blue dyeLangmuirMethyl blue02 engineering and technology010402 general chemistry01 natural sciencesBiochemistryInorganic Chemistrychemistry.chemical_compoundAdsorptionHydroxylamineMaterials ChemistryPhysical and Theoretical Chemistryferrocenecarboxaldehyde oximeta116single crystal X-ray diffractionAqueous solutionSchiff baseOrganic Chemistry021001 nanoscience & nanotechnologyOximeferrocene-based Schiff base0104 chemical sciencesFerrocenechemistryadsorption0210 nano-technologyNuclear chemistryJournal of Organometallic Chemistry
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Interaction of methyltin(IV) compounds with carboxylate ligands. Part 1: formation and stability of methyltin(IV)–carboxylate complexes and their rel…

2006

Quantitative data on the stability of mono-, di- and trimethyltin(IV)-carboxylate complexes (acetate, malonate, succinate, malate, oxydiacetate, diethylenetrioxydiacetate, tricarballylate, citrate, butanetetracarboxylate and mellitate) are reported at t=25°C and I → 0 mol l - 1 . Several mononuclear, mixed proton, mixed hydroxo and polynuclear species are formed in these systems. As expected, the stability trend is mono- > di- > trimethyltin(IV) and mono < di < tri < tetra < hexa for the organotin moieties and carboxylate ligands investigated, respectively. Moreover, ligands containing, in addition to carboxylic,-O-and-OH groups show a significantly higher stability with respect to analogou…

methyltin(IV) cationLigandStereochemistryMetal ions in aqueous solutionGeneral ChemistryHEXAMedicinal chemistryInorganic Chemistrymethyltin(IV)–carboxylate complexeschemistry.chemical_compoundMalonatechemistryspeciationStability constants of complexesmethyltin(IV) cationsChemical stabilitySettore CHIM/01 - Chimica AnaliticaCarboxylatemethyltin(IV)–carboxylate complexeBinding sitecarboxylate ligandmethyltin(IV) cations; carboxylate ligands; methyltin(IV)–carboxylate complexes; speciationcarboxylate ligands
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The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.

2021

Since the approval of the first monoclonal antibody (mAb) in 1986, a huge effort has been made to guarantee safety and efficacy of therapeutic mAbs. As of July 2021, 118 mAbs are approved for the European market for a broad range of clinical indications. In order to ensure clinical efficacy and safety aspects, (pre-)clinical experimental approaches evaluate the respective modes of action (MoA). In addition to antigen-specificity including binding affinity and -avidity, MoA comprise Fc-mediated effector functions such as antibody dependent cellular cytotoxicity (ADCC) and the closely related antibody dependent cellular phagocytosis (ADCP). For this reason, a variety of cell-based assays have…

modes of action (MoA)GlycosylationQH301-705.5medicine.drug_classCellReceptors FcReviewBiologyMonoclonal antibodyCatalysisInorganic Chemistrychemistry.chemical_compoundMonoklonaler Antikörper ; effector function ; antibody dependent cellular phagocytosis (ADCP) ; therapeutic monoclonal antibodies (mAbs) ; Fcγ receptor (FcγR) ; modes of action (MoA) ; antibody dependent cellular cytotoxicity (ADCC)medicineAnimalsHumansAvidityClinical efficacyBiology (General)Physical and Theoretical ChemistryReceptorQD1-999Molecular BiologySpectroscopyAntibody-dependent cell-mediated cytotoxicityEffectortherapeutic monoclonal antibodies (mAbs)Organic ChemistryAntibody-Dependent Cell CytotoxicityAntibodies Monoclonalantibody dependent cellular phagocytosis (ADCP)General MedicineFcγ receptor (FcγR)Computer Science ApplicationsImmunoglobulin Fc Fragmentsantibody dependent cellular cytotoxicity (ADCC)Chemistrymedicine.anatomical_structurechemistryImmunologyImmunotherapyeffector functionInternational journal of molecular sciences
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Polymorphism and Metallic Behavior in BEDT-TTF Radical Salts with Polycyano Anions

2012

Up to five different crystalline radical salts have been prepared with the organic donor BEDT-TTF and three different polynitrile anions. With the polynitrile dianion tcpd2− (=C[C(CN)2]32−), two closely related radical salts: α&#039;-(ET)4tcpd·THF (1) (THF = tetrahydrofurane) and α&#039;-(ET)4tcpd·H2O (2) have been prepared, depending on the solvent used in the synthesis. With the mono-anion tcnoetOH− (=[(NC)2CC(OCH2CH2OH)C(CN)2]−) two polymorphs with similar physical properties but different crystal packings have been synthesized: θ-(ET)2(tcnoetOH) (3) and β&#039;&#039;-(ET)2(tcnoetOH) (4). Finally, with the mono-anion tcnoprOH− (=[(NC)2CC(OCH2CH2CH2OH)C(CN)2]−) we have prepared a metallic…

molecular conductorsGeneral Chemical EngineeringInorganic chemistrybis(ethylenedithio)tetrathiafulvalene; polycyano anions; molecular conductors; synthetic metals02 engineering and technology010402 general chemistry01 natural sciencesMedicinal chemistrysynthetic metalsInorganic ChemistryMetalCrystalbis(ethylenedithio)tetrathiafulvalenelcsh:QD901-999[CHIM.CRIS]Chemical Sciences/Cristallography[CHIM]Chemical SciencesGeneral Materials Sciencepolycyano anionsChemistry021001 nanoscience & nanotechnologyCondensed Matter Physics0104 chemical sciencesSolventPolymorphism (materials science)visual_artvisual_art.visual_art_mediumlcsh:Crystallography0210 nano-technology
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Magneto-structural correlations in discrete $Mn^{II}‐W^V$ cyano‐bridged assemblies with polyimine ligands

2010

We present the magneto-structural correlations for two novel discrete cyano-bridged assemblies based on cationic complexes of manganese(II) with diimine ligands and octacyanotungstate(V) ions. The crystal structure of [Mn II (terpy)(dmf)-(H 2 O) 2 ][Mn II (terpy)(H 2 O)(dmf)(μ-NC)W V (CN) 7 ] 2· 6H 2 O (1) (terpy = 2,2';6',2"-terpyridine, dmf = dimethylformamide) contains dinuclear {Mn II W V } - cyano-bridged anions, while the crystal structure of [Mn II (phen) 3 ] 2 [MnII(phen) 2 (μ-NC) 2 -W V (CN) 6 ] 2 (ClO 4 ) 2 ·9H 2 O (2) (phen = 1,10-phenanthroline) is built of tetranuclear {Mn II 2 W V 2} 2- square anions. Intramolecular Mn-W magnetic interactions through the cyano bridges are repr…

molecular squaresStereochemistrytungstenstructure elucidationCationic polymerizationchemistry.chemical_elementcyanidesCrystal structureManganeseIonInorganic Chemistrychemistry.chemical_compoundCrystallographyAtomic orbitalchemistryIntramolecular forcemanganeseDimethylformamidemagnetic propertiesDiimine
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Structures and energetic properties of 4-halobenzamides

2018

The amide bond represents one of the most fundamental functional groups in chemistry. The properties of amides are defined by amidic resonance (nN→π*C=O conjugation), which enforces planarity of the six atoms comprising the amide bond. Despite the importance of 4-halo-substituted benzamides in organic synthesis, molecular interactions and medicinal chemistry, the effect of 4-halo-substitution on the properties of the amide bond in N,N-disubstituted benzamides has not been studied. Herein, we report the crystal structures and energetic properties of a full series of 4-halobenzamides. The structures of four 4-halobenzamides (halo = iodo, bromo, chloro and fluoro) in the N-morpholinyl series h…

morpholinyl amidescrystal structure010405 organic chemistryCrystal structure010402 general chemistryCondensed Matter PhysicsRing (chemistry)Resonance (chemistry)01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundCrystallographychemistryresonance energiestwisted amidesMorpholineAmideamide bondsHalogenMaterials ChemistryPeptide bondOrganic synthesisPhysical and Theoretical ChemistryActa Crystallographica Section C Structural Chemistry
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Excitation Transfer Engineering in Ce-Doped Oxide Crystalline Scintillators by Codoping with Alkali-Earth Ions

2018

This work has been supported by the European Social Fund Measure No. 09.3.3-LMT-K-712 activity Improvement of Researchers Qualification by Implementing the World-Class R&D Projects, and by grant #14.W03.31.0004 of the Russian Federation Government. Authors are grateful to CERN Crystal Clear Collaboration and COST Action TD1401 "Fast Advanced Scintillator Timing (FAST)" for support of collaboration.

multicomponent garnetsMaterials scienceInorganic chemistryexcitation transferscintillators02 engineering and technologyScintillator7. Clean energy01 natural sciencesDoped oxideIonfree carrier0103 physical sciences:NATURAL SCIENCES:Physics [Research Subject Categories]Materials ChemistryElectrical and Electronic EngineeringAlkaline earth metal010308 nuclear & particles physicsmulticomponent garnetfree carriersSurfaces and Interfaces021001 nanoscience & nanotechnologyCondensed Matter PhysicsFree carrierSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialsscintillator0210 nano-technologyExcitationphysica status solidi (a)
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Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives

2011

Topological-mathematical models based on multiple linear regression analyses have been built to predict the reaction yields and the anti-inflammatory activity of a set of heterocylic amidine derivatives, synthesized under environmental friendly conditions, using microwave irradiation. Two models with three variables each were selected. The models were validated by cross-validation and randomization tests. The final outcome demonstrates a good agreement between the predicted and experimental results, confirming the robustness of the method. These models also enabled the screening of virtual libraries for new amidine derivatives predicted to show higher values of reaction yields and anti-infl…

multilineal regression analysisQSAR analysisAmidinesAnti-Inflammatory AgentsQuantitative Structure-Activity RelationshipArticleCatalysismolecular topologylcsh:ChemistryInorganic ChemistryAmidineHeterocyclic Compounds 1-Ringchemistry.chemical_compoundComputational chemistryLinear regressionOrganic chemistryPhysical and Theoretical Chemistryyield reactionanti-inflammatory activitylcsh:QH301-705.5Molecular BiologySpectroscopyChemistryOrganic ChemistryGeneral MedicineComputer Science Applicationslcsh:Biology (General)lcsh:QD1-999Microwave irradiationMolecular topologyAlgorithmsamidine derivativesInternational Journal of Molecular Sciences
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Tolerance, Adaptation, and Cell Response Elicited by Micromonospora sp. Facing Tellurite Toxicity: A Biological and Physical-Chemical Characterization

2022

The intense use of tellurium (Te) in industrial applications, along with the improper disposal of Te-derivatives, is causing their accumulation in the environment, where oxyanion tellurite (TeO32&minus;) is the most soluble, bioavailable, and toxic Te-species. On the other hand, tellurium is a rare metalloid element whose natural supply will end shortly with possible economic and technological effects. Thus, Te-containing waste represents the source from which Te should be recycled and recovered. Among the explored strategies, the microbial TeO32&minus; biotransformation into less toxic Te-species is the most appropriate concerning the circular economy. Actinomycetes are ideal candidates in…

multivariate statistical analysisExtracellular Polymeric Substance MatrixSuperoxide DismutaseOrganic ChemistryGeneral MedicineSettore BIO/19 - Microbiologia Generalefatty acidsMicromonosporaCatalysisComputer Science ApplicationsInorganic ChemistryFTIR spectroscopyProtein Aggregatestellurite; bacterial cell membrane; cell morphology changes; fatty acids; FTIR spectroscopy; oxidative stress; heavy metals; multivariate statistical analysisbacterial cell membranecell morphology changesoxidative stressPhysical and Theoretical ChemistryTelluriumheavy metalstelluriteMolecular BiologySpectroscopy
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Intra-Articular Injection of Botulinum Toxin for the Treatment of Knee Osteoarthritis: A Systematic Review of Randomized Controlled Trials

2023

The purpose of the present paper was to review the available evidence on intra-articular botulinum toxin (BTX) injection in the treatment of knee osteoarthritis and to compare it to other conservative treatment options. A systematic review of the literature was performed on the PubMed, Scopus, Cochrane Library, Web of Science, Pedro and Research Gate databases with the following inclusion criteria: (1) randomized controlled trials (RCTs), (2) written in the English language, and (3) published on indexed journals in the last 20 years (2001–2021) dealing with the use of BTX intra-articular injection for the treatment of knee OA. The risk of bias was assessed using the Cochrane Risk of Bias to…

musculoskeletalSettore MED/34 - Medicina Fisica E RiabilitativaOrganic Chemistryintra-articularGeneral MedicineCatalysisComputer Science ApplicationsarthritiInorganic Chemistrysystematic reviewbotulinumtendinopathyPhysical and Theoretical ChemistryMolecular BiologySpectroscopyInternational Journal of Molecular Sciences
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