Search results for "Insulin"

showing 10 items of 1360 documents

Effects of high-intensity training on physiological and hormonal adaptions in well-trained cyclists

2017

Purpose: This study aimed to compare the effects of three different high-intensity training (HIT) models, balanced for total load but differing in training plan progression, on endurance adaptations. Methods: Sixty-three cyclists (peak oxygen uptake (V˙ O2peak) 61.3 T 5.8 mLIkgj1 Iminj1 ) were randomized to three training groups and instructed to follow a 12-wk training program consisting of 24 interval sessions, a high volume of low-intensity training, and laboratory testing. The increasing HIT group (n = 23) performed interval training as 4 16 min in weeks 1–4, 4 8 min in weeks 5–8, and 4 4 min in weeks 9–12. The decreasing HIT group (n = 20) performed interval sessions in the opposite me…

GerontologyAdultMalemedicine.medical_specialtyHydrocortisoneeducationProlactin bloodPhysical Therapy Sports Therapy and Rehabilitation030204 cardiovascular system & hematologyHigh-Intensity Interval TrainingBody Mass Index03 medical and health sciencesTestosterone blood0302 clinical medicinePhysical medicine and rehabilitationSex Hormone-Binding GlobulinmedicineHumansOrthopedics and Sports MedicineTestosteroneInsulin-Like Growth Factor Ibusiness.industryHuman Growth HormoneHigh intensity030229 sport sciencesAdaptation PhysiologicalHormonesBicyclingProlactinInsulin-Like Growth Factor Binding Protein 3Multicenter studyExercise Testbusiness
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Interventions to Slow Aging in Humans: Are We Ready?

2015

The workshop entitled 'Interventions to Slow Aging in Humans: Are We Ready?' was held in Erice, Italy, on October 8-13, 2013, to bring together leading experts in the biology and genetics of aging and obtain a consensus related to the discovery and development of safe interventions to slow aging and increase healthy lifespan in humans. There was consensus that there is sufficient evidence that aging interventions will delay and prevent disease onset for many chronic conditions of adult and old age. Essential pathways have been identified, and behavioral, dietary, and pharmacologic approaches have emerged. Although many gene targets and drugs were discussed and there was not complete consens…

GerontologyAgingDisease onsetPrescription DrugsLongevityPsychological interventionReviewsBiologyAMP-Activated Protein KinasesGrowth hormoneAging; Anti-aging; Centenarians; Dietary restriction; Lifespan studies; Longevity gene; Longevity regulation; Cell Biology; AgingDietary interventionsBiological FactorsMicelongevity geneSettore BIO/13 - Biologia ApplicataAnimalsHumansSirtuinsProtein restrictionCentenarianInsulin-Like Growth Factor ILifespan studieCaloric RestrictionSettore MED/04 - Patologia GeneraleGeroscienceGene targetsRibosomal Protein S6 KinasesTOR Serine-Threonine Kinasesanti-agingdietary restrictionCell Biologydietary restriction ; lifespan studies ; longevity gene ; centenarians ; anti-aging ; longevity regulation ; aginglongevity regulation3. Good healthDietEnzyme ActivationGene Expression RegulationGrowth HormoneGenetics of agingcentenariansaging; anti-aging; centenarians; dietary restriction; lifespan studies; longevity gene; longevity regulationSignal Transductionlifespan studies
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Differences in cardiometabolic risk profiles between Chinese and Finnish older adults with glucose impairment and central obesity.

2022

Abstract Background Obesity and ethnicity play important roles in cardiovascular complications in patients with type 2 diabetes mellitus (T2DM). This study aimed to compare cardiometabolic risk profiles between Chinese and Finnish older adults of central obesity with prediabetes or T2DM. Methods Study subjects were 60–74 years old and originated from two population samples. The Finnish subjects came from the Kuopio Ischemic Heart Disease (KIHD) study (n = 1089), and the Chinese subjects came from the Shanghai High-risk Diabetic Screen (SHiDS) study (n = 818). The KIHD and SHiDS studies used similar questionnaires to determine participants’ baseline characteristics regarding the history of m…

GerontologyBlood GlucoseChinaEndocrinology Diabetes and MetabolismEndocrinology and DiabetesPrediabetic StateEndocrinologyRisk FactorsType 2 diabetes mellitusEthnicitymedicineHumanssuomalaisetObesityFinlandTriglyceridesAgedCardiometabolic riskChinesebusiness.industryFinnishCholesterol HDLriskitekijätMiddle AgedkiinalaisetCardiovascular disease riskmedicine.diseaseObesityGlucoseDiabetes Mellitus Type 2Cardiovascular DiseasesCentral obesityObesity AbdominalEndokrinologi och diabetessydän- ja verisuonitauditlihavuusInsulin Resistancebusinessaikuistyypin diabetesJournal of endocrinological investigation
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El autoconcepto y la adaptación a la enfermedad en pacientes diabéticos pediátricos

2014

ResumenNuestro objetivo es estudiar el autoconcepto y la adaptación a la enfermedad en pacientes pediátricos diabéticos. Como instrumentos de evaluación se utilizaron el registro ad-hoc para las variables sociodemográficas y de enfermedad, el cuestionario de Autoconcepto Garley (CAG) y cuestionario de respuesta adaptativa a la enfermedad en pacientes diabéticos. La muestra constó de 23 sujetos evaluados en un único momento de medida, todos ellos niños y adolescentes entre 8 y 16 años de edad. Los resultados muestran cómo aproximadamente el 50% de niños y adolescentes con diabetes tipo I presentan un autoconcepto bajo en la mayoría de las dimensiones estudiadas, destacando cómo cerca del 30%…

GerontologyClinical PsychologyPediatricsmedicine.medical_specialtyDiabetes mellitus insulinodependientemedicineType i diabetesAutoconceptoAdaptaciónDiseasePsychologyEnfermedadClínica y Salud
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Intake of Total Polyphenols and Some Classes of Polyphenols Is Inversely Associated with Diabetes in Elderly People at High Cardiovascular Disease Ri…

2016

Background: Higher consumption of some polyphenols has been associated with a reduced risk of diabetes. However, no studies have evaluated the relation between all polyphenol subclasses and the incidence of diabetes.Objective: We aimed to prospectively examine the associations between the intake of total polyphenols and different groups of polyphenols (flavonoids, phenolic acids, stilbenes, lignans, and others) on the risk of incident diabetes in the PREDIMED (Prevencion con Dieta Mediterranea) trial.Methods: This was an observational cohort analysis of the nondiabetic participants in the PREDIMED trial. This study was a multicenter, controlled, randomized, parallel-group feeding trial to a…

GerontologyEuropean populationsmedicine.medical_specialtyDiabetes riskMediterranean dietMedicine (miscellaneous)030209 endocrinology & metabolismTotal-energy intake2 cohorts03 medical and health sciences0302 clinical medicineGlucose-metabolismMediterranean dietInternal medicineDiabetes mellitusEpidemiologymedicine030212 general & internal medicineglucoseDietary patternsFood sourcesNutrition and Dieteticscox regressionProportional hazards modelbusiness.industryIncidence (epidemiology)food and beveragesInsulin sensitivitymedicine.diseasePostmenopausal womenPolyphenolepidemiologyobservational studybusinesschronic diseaseRandomized-trialCohort studyThe Journal of Nutrition
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Effects of persistent physical activity and inactivity on coronary risk factors in children and young adults. The Cardiovascular Risk in Young Finns …

1994

The tracking of physical activity and its influence on selected coronary heart disease risk factors were studied in a 6-year (original survey in 1980, with follow-ups in 1983 and 1986) study of Finnish adolescents and young adults as part of the Cardiovascular Risk in Young Finns Study. The subjects in this analysis were aged 12, 15, and 18 years at baseline. Physical activity was assessed with a standardized questionnaire, and a sum index was derived from the product of intensity, frequency, and duration of leisure time physical activity. Complete data on physical activity index from each study year were available on 961 participants. Significant tracking of physical activity was observed …

GerontologyMaleAdolescentEpidemiologyCross-sectional studymedicine.medical_treatmentPhysiologyPhysical exercise03 medical and health scienceschemistry.chemical_compound0302 clinical medicineHigh-density lipoproteinRisk FactorsMedicineHumansInsulin030212 general & internal medicineObesityYoung adultRisk factorChildExerciseFinlandTriglyceridebusiness.industryInsulinSmoking030229 sport sciencesmedicine.diseaseObesityLipidsDietCross-Sectional StudieschemistryCardiovascular DiseasesRegression AnalysisFemalebusinessFollow-Up StudiesAmerican journal of epidemiology
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Work-loss years among people diagnosed with diabetes: a reappraisal from a life course perspective

2018

Aims Early exit from the workforce has been proposed to be one of the unfavorable consequences of diabetes. We examined whether early exit from the workforce differed between persons who were and were not diagnosed with diabetes during their work career. Methods The cohort included 12,726 individuals of the Helsinki Birth Cohort Study, born between 1934 and 1944. Using data from nationwide registers, the cohort was followed up from early adulthood until they transitioned into retirement or died. Work- loss years were estimated using the restricted mean work years method. Results During a follow-up of 382,328 person-years for men and 349 894 for women, 36.8% transitioned into old age pension…

GerontologyMaleAgingWorkIMPACTEpidemiologyEndocrinology Diabetes and MetabolismCohort StudiesMELLITUS0302 clinical medicineEndocrinologyDiabetes mellitusRisk FactorsEpidemiology030212 general & internal medicineRetirementDisability pensionGeneral MedicineMiddle AgedINSULINComputingMilieux_GENERALWork (electrical)WorkforceCohortGROWTHLife course approachOriginal ArticleFemaleCohort studyAdultmedicine.medical_specialtyLongevity030209 endocrinology & metabolismHEART-DISEASE03 medical and health sciencesPensionsDiabetes mellitusInternal MedicinemedicineHumansCOHORTDisabled PersonsEarly exit from workforceAgedComputingMilieux_THECOMPUTINGPROFESSIONbusiness.industryInformationSystems_INFORMATIONSYSTEMSAPPLICATIONSLife courseDisability pensionmedicine.diseaseComputingMethodologies_PATTERNRECOGNITION3121 General medicine internal medicine and other clinical medicineDiabetes medicationComputingMilieux_COMPUTERSANDSOCIETYFOLLOW-UPbusinessFollow-Up StudiesActa Diabetologica
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Psychosocial aspects of diabetes technology

2020

Aim To identify key psychosocial research in the domain of diabetes technology. Results Four trajectories of psychosocial diabetes technology research are identified that characterize research over the past 25 years. Key evidence is reviewed on psychosocial outcomes of technology use as well as psychosocial barriers and facilitating conditions of diabetes technology uptake. Psychosocial interventions that address modifiable barriers and psychosocial factors have proven to be effective in improving glycaemic and self-reported outcomes in diabetes technology users. Conclusions Psychosocial diabetes technology research is essential for designing interventions and education programmes targeting…

GerontologyTechnology researchEndocrinology Diabetes and MetabolismMEDLINEPsychological interventionInsulin delivery030209 endocrinology & metabolismHistory 21st Century03 medical and health sciences0302 clinical medicineEndocrinologyInsulin Infusion SystemsInventionsDiabetes mellitusInternal MedicinemedicineDiabetes MellitusHumansInsulinPsychology030212 general & internal medicinebusiness.industryDiabetes mellitus therapyHistory 20th Centurymedicine.diseaseEquipment and Supplies150 PsychologieRelated researchbusiness150 PsychologyPsychosocialBehavioral SciencesDelivery of Health Care
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CARDIOMETABOLIC SYNDROME AND SARCOPENIC OBESITY IN OLDER PERSONS

2007

The aging of the world's population is a major contributor to the growing prevalence of the cardiometabolic syndrome (CMS) because older persons are more affected by the constellation of cardiovascular risk factors that constitute the syndrome. The prevalence of CMS has been related to the increasing prevalence of obesity, which is growing progressively even among older age groups. Indeed, obesity and aging are 2 overlapping mounting public health problems. It is currently accepted that CMS predicts cardiovascular mortality and/or the development of type 2 diabetes mellitus, and this is also true in studies including older persons. CMS is further complicated by modifications in body composi…

Gerontologymedicine.medical_specialtyAgingEndocrinology Diabetes and MetabolismPopulationAdipokineCardiometabolic syndromeInternal MedicinemedicineHumansSarcopenic obesityObesityeducationhealth care economics and organizationsAgedMetabolic Syndromeeducation.field_of_studybusiness.industryPublic healthType 2 Diabetes Mellitusmedicine.diseaseObesityMuscular AtrophyAdipose TissueCardiovascular DiseasesSarcopeniaLean body massPhysical therapyBody CompositionInflammation MediatorsInsulin ResistanceCardiology and Cardiovascular MedicinebusinessHuman
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Main Problems of Diabetes Mellitus Type 2 Patients in Keeping Diet

2015

A research has been carried out to assess the awareness of patients about the importance of diet, the availability of information and to make the diabetes patients with mellitus type 2 realize the urgency of dieting. The first part looks into theoretical sources and statistics about how widespread diabetes mellitus type 2 is and the importance of a healthy diet. The practical part of the research consists of the survey results. The method of quantitative research was applied. The conclusions and suggestions have been made based on the research results.

Gerontologymedicine.medical_specialtybusiness.industryNon insulin dependent diabetes mellitusSurvey resultmedicine.diseaseHealthy dietEndocrinologyInternal medicineDiabetes mellitusMedicinediabetes mellitus; diet; information; non insulin-dependent; problem; type 2medicine.symptombusinessDietingSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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