Search results for "Integument"
showing 10 items of 754 documents
Procollagen C-proteinase Enhancer Stimulates Procollagen Processing by Binding to the C-propeptide Region Only*
2011
Background: Procollagen C-proteinase enhancer-1 (PCPE-1) is an extracellular glycoprotein that increases activity of certain zinc metalloproteinases involved in tissue development and repair. Results: PCPE-1 binds uniquely to the C-propeptide region of the procollagen molecule. Conclusion: PCPE-1 enhances proteolysis by binding solely to the procollagen C-propeptides. Significance: These data may lead to future applications in the development of antifibrotic therapies.
Achievement of thermotolerance through hsps phosphorylation in sea urchin embryos.
1995
TPA treatment of sea urchin embryos is able to induce thermotolerance. Evidence is provided that TPA treatment induces phosphorylation of a constitutive stress protein of 38 KDa.
Immunological detection of phenylalanine hydroxylase protein in Drosophila melanogaster.
1992
A monoclonal antibody raised against monkey liver phenylalanine hydroxylase (PAH) has been used to detect this protein in Drosophila melanogaster. A cross-reacting material (CRM) band of apparent molecular mass 50-52 kDa, equivalent to that deduced for the Drosophila melanogaster PAH protein based on the pah gene cDNA sequence, has been detected. This CRM was analysed throughout development and showed an equivalent pattern to that reported for PAH activity in this insect, with maxima at pupariation and at pharate adult formation. Distribution of this CRM in larval tissues, the haemolymph and the adult body is mainly restricted to the larval fat body and the adult head. Demonstration of this…
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.
2008
Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …
Lipocalins in Arthropod Chemical Communication.
2021
Abstract Lipocalins represent one of the most successful superfamilies of proteins. Most of them are extracellular carriers for hydrophobic ligands across aqueous media, but other functions have been reported. They are present in most living organisms including bacteria. In animals they have been identified in mammals, molluscs, and arthropods; sequences have also been reported for plants. A subgroup of lipocalins, referred to as odorant-binding proteins (OBPs), mediate chemical communication in mammals by ferrying specific pheromones to the vomeronasal organ. So far, these proteins have not been reported as carriers of semiochemicals in other living organisms; instead chemical communicatio…
Kinetics of solid-state fermentation of lupin with Rhizophus oligosporus based on nitrogen compounds balance
2021
Solid-state fermentation could be a potentially effective method for improving the nutritional value of legumes. The objective of this study was to explore this technology in Lupinus mutabilis, a species of lupin, using a strain of Rhizopus oligosporus mold for solid-state fermentation. Three L. mutabilis varieties (INIAP-450, INIAP-451, and Criollo) were evaluated, including the effect of the grain status (whole or ground) and integument or husk (presence or absence). Kinetic parameters of the fermentation process were studied to define the specific speed of nitrogen formation and the digestibility and nutritional quality of the resulting protein. After incubation at 28 °C for 96 h, the ti…
Phantoms Used for Mapping of Skin Chromophores by Multi-spectral Imaging
2014
Skin phantoms can be used for better understanding of diffuse reflectance imaging of skin. In this study, skin phantoms of hemoglobin, bilirubin and melanin were developed and studied for possibilities to calibrate chromophore concentration values.
Local flap reconstruction of large scalp defects
2008
Scalp defects can have a number of origins, and their repair is dependent upon their location, size and depth. In the case of the scalp, the repair of even small defects is complicated. Local flaps are the reference for the reconstruction of such defects. Knowledge of scalp anatomy is essential for preparing these flaps, which must be based on one or two vascular pedicles to afford a large rotation angle ? thereby facilitating closure of the defect. The parietal zone is the location offering the greatest flap mobilization possibilities. We present a case involving the repair of a major pericranial frontoparietal scalp defect. A local transverse posterior transpositioning scalp flap was rais…
The effects of combined diamond microdermabrasion and a mixture of cosmetic acids on the condition of acne prone skin: a case report
2021
Background: Exfoliating treatments are widely used in cosmetology and dermatology forthe treatment of skin lesions and, above all, toreduce the number of skin eruptions that occur with acne vulgaris. An effective treatment that can be offered to people suffering from this disease is diamond microdermabrasion. The addition of acid peeling to this treatment may lead to even better results than in the case of monotherapy. Aim of the study: To assess the effectiveness of a combination of microdermabrasion and acid peeling on a 21-year-old woman suffering from acne vulgaris. Case report: The patient suffered from acne vulgaris, too high a level of sebum on the entire surface of the face, and, ov…
Additional file 7: of Characterization of disease-specific cellular abundance profiles of chronic inflammatory skin conditions from deconvolution of …
2019
Figure S4. Changes in cellular composition due to UVB phototherapy. Comparison of the abundance of various cell types in the lesional and non-lesional skin of patients with atopic dermatitis before and after narrow-band UVB phototherapy. Expression data from dataset GSE27887 [35] was used for this analysis. The p-value of each comparison is presented above each beanplot. (PDF 863 kb)