Search results for "Interaction"
showing 10 items of 5710 documents
Stromal Interaction Molecule 1 (STIM1) Is Involved in the Regulation of Mitochondrial Shape and Bioenergetics and Plays a Role in Oxidative Stress
2012
Calcium ions are involved in a plethora of cellular functions including cell death and mitochondrial energy metabolism. Store-operated Ca(2+) entry over the plasma membrane is activated by depletion of intracellular Ca(2+) stores and is mediated by the sensor STIM1 and the channel ORAI1. We compared cell death susceptibility to oxidative stress in STIM1 knock-out and ORAI1 knockdown mouse embryonic fibroblasts and in knock-out cells with reconstituted wild type and dominant active STIM1. We show that STIM1 and ORAI1 deficiency renders cells more susceptible to oxidative stress, which can be rescued by STIM1 and ORAI1 overexpression. STIM1 knock-out mitochondria are tubular, have a higher Ca…
Insect oviposition induces volatile emission in herbaceous plants that attracts egg parasitoid
2003
SUMMARYThe egg parasitoid Trissolcus basalis (Wollaston) (Hymenoptera:Scelionidae) responded to synomones emitted by leguminous plants induced by feeding and oviposition activity of the bug Nezara viridula (L.)(Heteroptera: Pentatomidae). This was shown by laboratory bioassays using a Y-tube olfactometer. Broad bean leaves (Vicia faba L.) damaged by feeding activity of N. viridula and on which host egg mass had been laid produced synomones that attracted T. basalis. By contrast,undamaged leaves or feeding-damaged leaves without eggs did not attract wasp females. French bean plants (Phaseolus vulgaris L.) also emitted attractive synomones when they were damaged by host feeding and carrying e…
Three proteins regulating integrin function - filamin, 14-3-3 and RIAM
2011
Interactions of α2β1 integrin and its ligands, type I collagen and echovirus 1
2015
TPACK and Educational Interactions : Pillars of Successful Technology Integration
2019
It is important to understand what drives the success of technology integration in educational settings, because learning in schools with technology develops the students' capacities to participate fully in the digital age. Educated students, in turn, can transform our societies through innovative scientific discoveries. Recently, the Technological Pedagogical Content Knowledge (TPACK) framework has emerged as a theoretical framework needed for understanding the teacher’s integration of digital technologies into teaching. Educational interactions, in turn, have been emphasized as a critical component of the educational practices, processes and contexts. However, these two concepts have been…
Hume’s Guillotine in Designing Ethically Intelligent Technologies
2020
Intelligent machines can follow ethical rules in their behaviour. However, it is less clear whether intelligent systems can also create new ethical principles. The former position can be called weak ethical AI and the latter strong ethical AI. Hume’s guillotine which claims that one cannot derive values from facts appears to be a fundamental obstacle to strong ethical AI. The analysis of human ethical information processes provides clarity to the possibility of strong ethical AI. Human ethical information processing begins with positive of negative emotions associated to situations. Situations can be seen as consequences of actions and for this reason people can define rules about acceptabi…
Editorial:Governance AI ethics
2022
Towards intelligibility and shared understanding : co-construction of meaning in ELF interaction
2011
Tutkielman tarkoituksena on selvittää, mitä vuorovaikutuksen keinoja puhujat käyttävät ymmärrettävyyden ja yhteisen ymmärryksen saavuttamiseksi keskusteluissa, joissa englanti toimii lingua francana (ELF) eli yhteisenä kielenä eri kieli- ja kulttuuritaustaisten puhujien kesken. Tutkielman tavoitetta lähestytään etsimällä vastauksia seuraaviin kysymyksiin: 1) Miten ELF-puhujat neuvottelevat ja luovat yhdessä merkityksiä sanoille vuorovaikutuksen aikana?, 2) Kuinka ymmärtämiseen (tai kuulemiseen) liittyvät ongelmat ratkaistaan keskustelussa? ja 3) Millä tavoin luovuutta hyödynnetään merkitysneuvotteluissa? Tutkimuksen metodina käytetään keskustelunanalyysia ja teoreettinen viitekehys muodostu…
Measurement of the low-energy antideuteron inelastic cross section
2020
In this Letter, we report the first measurement of the inelastic cross section for antideuteron-nucleus interactions at low particle momenta, covering a range of $0.3 \leq p < 4$ GeV/$c$. The measurement is carried out using p-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of $\sqrt{s_{\rm{NN}}}$ = 5.02 TeV, recorded with the ALICE detector at the CERN LHC and utilizing the detector material as an absorber for antideuterons and antiprotons. The extracted raw primary antiparticle-to-particle ratios are compared to the results from detailed ALICE simulations based on the GEANT4 toolkit for the propagation of antiparticles through the detector material. The analysis of th…
Measurement of Atmospheric Neutrino Oscillations at 6–56 GeV with IceCube DeepCore
2018
We present a measurement of the atmospheric neutrino oscillation parameters using three years of data from the IceCube Neutrino Observatory. The DeepCore infill array in the center of IceCube enables the detection and reconstruction of neutrinos produced by the interaction of cosmic rays in Earth's atmosphere at energies as low as ∼5 GeV. That energy threshold permits measurements of muon neutrino disappearance, over a range of baselines up to the diameter of the Earth, probing the same range of L/Eν as long-baseline experiments but with substantially higher-energy neutrinos. This analysis uses neutrinos from the full sky with reconstructed energies from 5.6 to 56 GeV. We measure Δm322=2.31…