Search results for "Interactions"
showing 10 items of 1963 documents
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs.
2001
ABSTRACT Subgenomic selectable RNAs of the hepatitis C virus (HCV) have recently been shown to self-replicate to high levels in the human hepatoma cell line Huh-7 (V. Lohmann, F. Körner, J. O. Koch, U. Herian, L. Theilmann, and R. Bartenschlager, Science 285:110–113, 1999). Taking advantage of this cell culture system that allows analyses of the interplay between HCV replication and the host cell, in this study we characterized two replicon-harboring cell lines that have been cultivated for more than 1 year. During this time, we observed no signs of cytopathogenicity such as reduction of growth rates or ultrastructural changes. High levels of HCV RNAs were preserved in cells passaged under…
ELITA consensus statements on the use of DAAs in liver transplant candidates and recipients
2017
International audience; The advent of safe and highly effective direct-acting antiviral agents (DAAs) has had huge implications for the hepatitis C virus (HCV) transplant field, and changed our management of both patients on the waiting list and those with HCV graft re-infection after liver transplantation (LT). When treating HCV infection before LT, HCV re-infection of the graft can be prevented in nearly all patients. In addition, some candidates show a remarkable clinical improvement and may be delisted. Alternatively, HCV infection can be treated post-LT either soon after the transplant, taking advantage of the removal of the infected native liver, or at the time of disease recurrence, …
Contrasting reproductive traits of competing parasitoids facilitate coexistence on a shared host pest in a biological control perspective
2022
BACKGROUND: Interspecific competition in insect parasitoids is an important ecological phenomenon that has relevant implications for biological pest control. To date, interspecific intrinsic (=larval) competition has been intensively studied, while investigations on extrinsic (=adult) competition have often lagged behind. In this study we examined the role played by parasitoid reproductive traits and host clutch size on the outcome of extrinsic competition between Trissolcus basalis (Wollaston) and Ooencyrtus telenomicida (Vassiliev), two egg parasitoids of the pest Nezara viridula (L). Laboratory experiments were conducted by allowing both parasitoid species to exploit an egg mass made of …
THE EFFECTS OF MATING SYSTEM AND GENETIC VARIABILITY ON SUSCEPTIBILITY TO TREMATODE PARASITES IN A FRESHWATER SNAIL, LYMNAEA STAGNALIS
2004
The amount and distribution of genetic variability in host populations can have significant effects on the outcome of host-parasite interactions. We studied the effect of mating system and genetic variability on susceptibility of Lymnaea stagnalis snails to trematode parasites. Mating system of snails from eight populations differing in the amount of genetic variability was manipulated, and self- and cross-fertilized offspring were exposed to naturally occurring trematode parasites in a controlled lake experiment. Susceptibility of snails varied between populations, but mating-system treatment did not have a significant effect. Heterozygosity of snails was negatively correlated with the pro…
Competitive interactions are mediated in a sex-specific manner by arbuscular mycorrhiza in Antennaria dioica
2017
Plants usually interact with other plants, and the outcome of such interaction ranges from facilitation to competition depending on the identity of the plants, including their sexual expression. Arbuscular mycorrhizal (AM) fungi have been shown to modify competitive interactions in plants. However, few studies have evaluated how AM fungi influence plant intraspecific and interspecific interactions in dioecious species. The competitive abilities of female and male plants of Antennaria dioica were examined in a greenhouse experiment. Females and males were grown in the following competitive settings: (i) without competition, (ii) with intrasexual competition, (iii) with intersexual competitio…
Neutrino Structure Functions from GeV to EeV Energies
2023
The interpretation of present and future neutrino experiments requires accurate theoretical predictions for neutrino-nucleus scattering rates. Neutrino structure functions can be reliably evaluated in the deep-inelastic scattering regime within the perturbative QCD (pQCD) framework. At low momentum transfers ($Q^2 \le {\rm few}$ GeV$^2$), inelastic structure functions are however affected by large uncertainties which distort event rate predictions for neutrino energies $E_\nu$ up to the TeV scale. Here we present a determination of neutrino inelastic structure functions valid for the complete range of energies relevant for phenomenology, from the GeV region entering oscillation analyses to …
Scalar, axial-vector, and tensor resonances from the rho D-*, omega D-* interaction in the hidden gauge formalism
2009
13 pages, 15 figures.-- PACS nrs.: 13.75.Lb, 12.40.Vv, 12.40.Yx, 14.40.Cs.-- ArXiv pre-print available at: http://arxiv.org/abs/0903.3823
Vacuum local and global electromagnetic self-energies for a point-like and an extended field source
2013
We consider the electric and magnetic energy densities (or equivalently field fluctuations) in the space around a point-like field source in its ground state, after having subtracted the spatially uniform zero-point energy terms, and discuss the problem of their singular behavior at the source's position. We show that the assumption of a point-like source leads, for a simple Hamiltonian model of the interaction of the source with the electromagnetic radiation field, to a divergence of the renormalized electric and magnetic energy density at the position of the source. We analyze in detail the mathematical structure of such singularity in terms of a delta function and its derivatives. We als…
Measurement of CP asymmetry in D 0 → K - K + and D 0 → π - πdecays
2014
Time-integrated $CP$ asymmetries in $D^0$ decays to the final states $K^- K^+$ and $\pi^- \pi^+$ are measured using proton-proton collisions corresponding to $3\mathrm{\,fb}^{-1}$ of integrated luminosity collected at centre-of-mass energies of $7\mathrm{\,Te\kern -0.1em V}$ and $8\mathrm{\,Te\kern -0.1em V}$. The $D^0$ mesons are produced in semileptonic $b$-hadron decays, where the charge of the accompanying muon is used to determine the initial flavour of the charm meson. The difference in $CP$ asymmetries between the two final states is measured to be \begin{align} \Delta A_{CP} = A_{CP}(K^-K^+)-A_{CP}(\pi^-\pi^+) = (+0.14 \pm 0.16\mathrm{\,(stat)} \pm 0.08\mathrm{\,(syst)})\% \ . \nonu…
Hidden charm N and Delta resonances with heavy-quark symmetry
2013
A model is developed to describe odd-parity baryon resonances generated dynamically through a unitary baryon-meson coupled-channels approach. The scheme applies to channels with light- and/or heavy-quark content. Distinct features of the model are that i) the interaction is an S-wave contact one, ii) it reduces to the SU(3) Weinberg-Tomozawa Hamiltonian when light pseudoscalar mesons are involved, thus respecting chiral symmetry, iii) spin-flavor is preserved in the light-quark sector, and iv) heavy-quark spin symmetry is fulfilled in the heavy-quark sector. In particular, baryon-meson states with different content in c or in (c) over bar do not mix. The model is a minimal one and it contai…