Search results for "Interleukin 13"

showing 3 items of 23 documents

Anti-type2-Antibodies Specifically Inhibit Murine Asthma Features Induced By Intranasal Application of IL-5 and IL-13

2016

biologybusiness.industryImmunologymedicine.diseaseImmunologyInterleukin 13biology.proteinImmunology and AllergyMedicineNasal administrationAntibodybusinessInterleukin 5AsthmaJournal of Allergy and Clinical Immunology
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Individual and Synergistic Effects of IL-5 and IL-13 on Trans-Compartmental Activation and Migration of Eosinophils and Murine Asthma Features

2016

business.industryImmunologyInterleukin 13ImmunologymedicineImmunology and Allergymedicine.diseasebusinessInterleukin 5AsthmaJournal of Allergy and Clinical Immunology
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Osteoprotegerin expression in liver is induced by IL-13 through TGF-β

2020

1.AbstractBackgroundsOsteoprotegerin (OPG) is a profibrotic mediator produced by myofibroblasts under influence of transforming growth factor β (TGFβ). Its expression in experimental models of liver fibrosis correlates well with disease severity and treatment responses. The regulation of OPG in liver tissue is largely unknown and we therefore set out to elucidate which growth factors/interleukins associated with fibrosis induce OPG and through which pathways.MethodsPrecision-cut liver slices of wild type and STAT6-deficient mice and 3T3 fibroblasts were used to investigate the effects of TGFβ, interleukin (IL) 13 (IL13), IL1β, and platelet-derived growth factor BB (PDGF-BB) on expression of…

musculoskeletal diseasesChemistryGrowth factormedicine.medical_treatmentmedicine.diseaseAP-1 transcription factorOsteoprotegerinDownregulation and upregulationFibrosisInterleukin 13medicineCancer researchGalunisertibTransforming growth factor
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