Search results for "International HapMap Project"

showing 2 items of 12 documents

PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity in Latvians, Lithuanians and Taiwanese

2014

PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827) and PSMA3 (rs2348071) genetic diversity was investigated in 1438 unrelated subjects from Latvia, Lithuania and Taiwan. In general, polymorphism of each individual locus showed tendencies similar to determined previously in HapMap populations. Main differences concern Taiwanese and include presence of rs2277460 rare allele A not found before in Asians and absence of rs2295827 rare alleles homozygotes TT observed in all other human populations. Observed patterns of SNPs and haplotype diversity were compatible with expectation of neutral model of evolution. Linkage disequilibrium between the rs2295826 and rs2295827 was detected to be c…

UPS ubiquitin–proteasome systemLinkage disequilibriumTF transcription factorLD linkage disequilibriumPopulationSNPLocus (genetics)Single-nucleotide polymorphismBiologyArticleHapMap JPT JapaneseGenetic diversityHuman populationTW Taiwanese populationLT Lithuanian populationGeneticsInternational HapMap ProjectAlleleeducationHapMap-CEU NorthWestern EuropeansGenetics (clinical)Geneticseducation.field_of_studyGenetic diversityProteasomeHapMap HCB Han ChineseHWE Hardy–Weinberg equilibriumHaplotypePSMC6LV Latvian populationT2DM type 2 diabetes mellitusPSMA6SNP single nucleotide polymorphismTFBS transcription factor binding sitePSMA3Meta Gene
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Genome-wide analysis of Italian sheep diversity reveals a strong geographic pattern and cryptic relationships between breeds

2014

Summary Italy counts several sheep breeds, arisen over centuries as a consequence of ancient and recent genetic and demographic events. To finely reconstruct genetic structure and relationships between Italian sheep, 496 subjects from 19 breeds were typed at 50K single nucleotide polymorphism loci. A subset of foreign breeds from the Sheep HapMap dataset was also included in the analyses. Genetic distances (as visualized either in a network or in a multidimensional scaling analysis of identical by state distances) closely reflected geographic proximity between breeds, with a clear north–south gradient, likely because of high levels of past gene flow and admixture all along the peninsula. Sa…

multidimensional scalingOvis ariesGenotypeanalysisIntrogressionContext (language use)BiologyBreedinggenetic diversity; genetic structure; genome-wide single nucleotide polymorphisms; multidimensional scaling; neighbor network; Ovis aries; oviniPolymorphism Single Nucleotidegenome-widegenome-wide single nucleotide polymorphisms; multidimensional scaling; neighbor networksingle nucleotide polymorphismsgenetic diversity; genetic structure; genome-wide; single nucleotide polymorphisms; multidimensional scaling; neighbor network; Ovis ariesGeneticsgenetic structureAnimalsneighbor networkInternational HapMap ProjectGeneticsGenetic diversityGenomeSheepSettore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICOgenome-wide single nucleotide polymorphismsGenetic VariationGeneral Medicinegenetic diversitybiology.organism_classificationBreedMouflonPhylogeographyItalyEvolutionary biologyoviniGenetic structureAnimal Science and ZoologyrevealsGenetic isolate
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