Search results for "Interrupt"
showing 10 items of 61 documents
Is the nonREM–REM sleep cycle reset by forced awakenings from REM sleep?
2002
In selective REM sleep deprivation (SRSD), the occurrence of stage REM is repeatedly interrupted by short awakenings. Typically, the interventions aggregate in clusters resembling the REM episodes in undisturbed sleep. This salient phenomenon can easily be explained if the nonREM–REM sleep process is continued during the periods of forced wakefulness. However, earlier studies have alternatively suggested that awakenings from sleep might rather discontinue and reset the ultradian process. Theoretically, the two explanations predict a different distribution of REM episode duration. We evaluated 117 SRSD treatment nights recorded from 14 depressive inpatients receiving low dosages of Trimipram…
Double inlet left ventricular main chamber, subaortic small left sided right ventricle and interrupted aortic arch type A. What operation is indicate…
1987
A case of a 23 year old female patient who suffered from the complex congenital heart lesion of a double inlet left ventricular main chamber, subaortic small left sided right ventricle and interrupted aortic arch type A is reported. With equally high blood pressures, the perfusion in the upper half of the body was maintained through the ascending aorta while the lower half and the lungs were supplied through the pulmonary artery and a patent ductus arteriosus (PDA). Angiographically, the bulbo-ventricular foramen appeared to be nonrestrictive. However, distinct signs of muscular subaortic stenosis were detected. The hemodynamic status principally allowed surgical correction when this became…
Effect of a distal weight-bearing implant on visual analog scale scores in 23 transfemoral amputees.
2018
The objective of this interrupted time series clinical trial was to evaluate the effect of a distal weight-bearing implant on well-being in patients with transfemoral amputations using the visual analog scale (VAS). A total of 29 patients from five hospitals with previous transfemoral amputations were surgically implanted with an osseoanchored implant with a distal spacer that allows a direct load on the residuum over the distal surface of the socket. Patients were followed for a 14-month period and assessed presurgically and postsurgically using the VAS. The Wilcoxon test was used to evaluate the differences between variables. VAS mean scores improved significantly after intervention. Sign…
Don't stop me now: Hampered retrieval of action plans following interruptions
2020
How can we retrieve action plans in working memory (WM) after being distracted or interrupted? The present EEG study investigated this question using a WM task in which a random sequence of single numbers (1-4 and 6-9) was presented. In a given trial, participants had to decide whether the number presented in the preceding trial was odd or even. Additionally, interfering stimuli were randomly presented in 25% of all trials, requiring the participants to either ignore a colored number (distraction) or respond to it (interruption) while maintaining the previously formed action plan in WM. Our results revealed a detrimental impact of interruptions on WM performance in trials after interrupting…
Does the Compliance to Intravesical BCG Differ between Common Clinical Practice and International Multicentric Trials?
2015
<b><i>Introduction:</i></b> The aim of this study was to analyze the reasons for intravesical BCG interruption in clinical practice. BCG for at least one year is advocated as the best regimen to treat high-risk non-muscle invasive bladder cancer (NMIBC). However, almost 50% of patients don't complete it. Toxicity accounts for 10% of dropouts in international trials. <b><i>Materials and Methods:</i></b> Patients with T1HG NMIBC undergoing 1-year BCG were enrolled in this study. BCG was administered for one year. Toxicity and causes of treatment interruption were recorded. <b><i>Results:</i></b> A total of 411 patients we…
Use of long acting injectable aripiprazole before and through pregnancy in bipolar disorder: a case report
2019
Abstract Background Long-acting injectable (LAI) antipsychotics for psychotic disorders provide advantages in treatment compliance, but data on their use in pregnancy are very limited. We present a clinical case of aripiprazole LAI use in pregnancy. Case presentation A 43-year-old woman diagnosed with bipolar disorder, with several relapses due to treatment interruption while trying to conceive. Finally, aripiprazole LAI treatment was planned by mutual agreement between doctor and the patient, who took aripiprazole LAI before and during pregnancy. She gave birth at 40 weeks to a 3500 g baby girl with no congenital malformations, who was healthy at 5 months after delivery. Conclusion As far …
Intravesical mitoxantrone in superficial bladder tumours (Ta-T1)
1993
Abstract 36 patients with histologically proven grade G1–G2, Ta-T1 transitional cell carcinoma of the bladder were introduced, after transurethral resection (TUR), into a study of intravesical chemoprophylaxis with mitoxantrone (20 mg diluted in 50 ml). After a mean follow-up of 23 months, 16 (50%) patients showed a superficial recurrence with a mean recurrence rate of 0.56 per year. In 19 patients with recurring tumours the mean recurrence rate decreased from 1.65 to 0.58 per year. 9 patients (25.7%) suffered from a chemical cystitis that in 2 cases (5.7%) required treatment interruption.
Methodological considerations for interrupted time series analysis in radiation epidemiology: an overview
2021
Interrupted time series analysis (ITSA) is a method that can be applied to evaluate health outcomes in populations exposed to ionizing radiation following major radiological events. Using aggregated time series data, ITSA evaluates whether the time trend of a health indicator shows a change associated with the radiological event. That is, ITSA checks whether there is a statistically significant discrepancy between the projection of a pre-event trend and the data empirically observed after the event. Conducting ITSA requires one to consider specific methodological issues due to unique threats to internal validity that make ITSA prone to bias. We here discuss the strengths and limitations of …
Circuit Breakers – a legal analysis of volatility safeguards in the rules of stock exchanges on the occasion of the COVID-19 crisis
2020
Abstract This paper examines circuit breakers (CBs), i. e. emergency systems of trading venues that interrupt or restrain trading when significant price movements of financial instruments occur. After a description of the ratio legis and the economic fundamentals, the genesis and the different forms of CBs are presented. The European legal framework is then outlined. The relevant rules of the Frankfurt Stock Exchange (FWB) serve as an example.
Robust model-following control of parallel UPS single-phase inverters
2008
This paper presents a robust control technique applied to modular uninterruptible power-supply (UPS) inverters operating in parallel. When compared to conventional proportional-integral (PI) control, the proposed technique improves the response of the output voltage to load steps and to high distorted output currents, reducing the distortion of the output voltage. Furthermore, an excellent distribution of currents between modules is achieved, resulting in fine power equalization between the inverters on stream. The crossover frequency of the different loop gains involved is moderate, so that robustness to variations of the operation point and to modeling uncertainties is achieved. A compara…