Search results for "Interventional"

showing 10 items of 300 documents

Combining split-and-merge and multi-seed region growing algorithms for uterine fibroid segmentation in MRgFUS treatments

2016

Uterine fibroids are benign tumors that can affect female patients during reproductive years. Magnetic resonance-guided focused ultrasound (MRgFUS) represents a noninvasive approach that uses thermal ablation principles to treat symptomatic fibroids. During traditional treatment planning, uterus, fibroids, and surrounding organs at risk must be manually marked on MR images by an operator. After treatment, an operator must segment, again manually, treated areas to evaluate the non-perfused volume (NPV) inside the fibroids. Both pre- and post-treatment procedures are time-consuming and operator-dependent. This paper presents a novel method, based on an advanced direct region detection model, …

SpeedupUterine fibroidsImage ProcessingBiomedical EngineeringThermal ablation02 engineering and technologyMagnetic Resonance Imaging InterventionalFocused ultrasound030218 nuclear medicine & medical imaging03 medical and health sciencesComputer-Assisted0302 clinical medicineImage Processing Computer-Assisted0202 electrical engineering electronic engineering information engineeringmedicineHumansSegmentationRadiation treatment planningSplit-and-merge segmentationSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniMRgFUS treatmentsInterventionalLeiomyomaMulti-seed adaptive region growingbusiness.industrymedicine.diseaseMagnetic Resonance Imagingfemale genital diseases and pregnancy complicationsComputer Science ApplicationsAutomatic segmentation MRgFUS treatments Multi-seed adaptive region growing Split-and-merge segmentation Uterine fibroids Algorithms Female High-Intensity Focused Ultrasound Ablation Humans Leiomyoma Magnetic Resonance Imaging Magnetic Resonance Imaging Interventional Image Processing Computer-AssistedMRgFUS treatmentRegion growingAutomatic segmentation; MRgFUS treatments; Multi-seed adaptive region growing; Split-and-merge segmentation; Uterine fibroids; Algorithms; Female; High-Intensity Focused Ultrasound Ablation; Humans; Leiomyoma; Magnetic Resonance Imaging; Magnetic Resonance Imaging Interventional; Image Processing Computer-AssistedHigh-Intensity Focused Ultrasound AblationFemale020201 artificial intelligence & image processingAutomatic segmentationbusinessMerge (version control)AlgorithmAlgorithmsUterine fibroidsMedical & Biological Engineering & Computing
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MRgFUS results Italy

2017

PURPOSE: To present our preliminary results achieved with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. Moreover, to our knowledge, this is the world-first tcMRgFUS system ever installed on a 1.5T MRI unit. Technical issues faced to achieve a safe and effective treatment will be discussed focusing on MR high-resolution live imaging and thermometry sequences optimization. METHOD AND MATERIALS: Patient enrollment was based on indication for functional neurosurgery and evidence of medication-refractory disease; a detailed medical history has been collected together with a complete clinical examin…

Stereotaxic TechniquesBrain; High-Intensity Focused Ultrasound ablation; Magnetic Resonance Imaging Interventional; Minimally Invasive Surgical Procedures; Stereotaxic TechniquesHigh-Intensity Focused Ultrasound ablationSettore MED/27 - NeurochirurgiaBrainSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaMinimally Invasive Surgical ProcedureMagnetic Resonance Imaging InterventionalSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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MR-guided focused ultrasound application for moving target tumor ablation in abdominal area: Coil selection

2020

PubMed: 32276552

SwineThermal ablationMagnetic Resonance Imaging InterventionalTumor ablationFocused ultrasound030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery03 medical and health sciencesCE marking0302 clinical medicineEcho planar imagingAbdomenAnimalsHumansMedicineRadiology Nuclear Medicine and imagingRadiological and Ultrasound TechnologyEcho-Planar ImagingPhantoms Imagingbusiness.industryCoils magnetic resonance thermometry tracking echo planar imaging magnetic resonance-guided focused-ultrasound surgery CE marking validation verificationTrackingLiver NeoplasmsVerificationSettore MED/37 - NeuroradiologiaCoilsGeneral MedicineFocused ultrasound surgeryDisease Models AnimalLiverMagnetic resonance thermometryElectromagnetic coil030220 oncology & carcinogenesisHigh-Intensity Focused Ultrasound AblationbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaMri guidedMagnetic resonance thermometryBiomedical engineering
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Interventistica eco-guidata per l’articolazione d’anca

2013

Lo scopo di questo lavoro è di rivedere le principali applicazioni della interventistica eco-guidata d’anca, descrivendone le indicazioni e la metodologia. L’ecografia è una metodica considerata sicura per i pazienti, in quanto non è stato dimostrato un possibile danno dovuto all’energia trasmessa dagli ultrasuoni ai tessuti del paziente, contrariamente alle metodiche che fanno uso di radiazioni ionizzanti, come la radiografia convenzionale e la tomografia computerizzata. Inoltre, l’ecografia risulta rapida ed efficace nel guidare l’ago verso la sede voluta evitando di intercettare strutture vascolari e/o nervose, consentendo quindi una maggiore sicurezza, rispetto alle tecniche interventis…

The purpose of this work is to review the main applications of ultrasound-guided hip intervention al procedures describing the indications and methodology. Ultrasound is a method considered safe for patients as it has not been shown a possible damage due to ultrasound energy transmitted towards the patient's tissues as opposed to methods that make use of ionizing radiation such as conventional radiography and computed tomography. In addition ultrasound is quick and effective in guiding the needle to the desired location avoiding vascular and/or nerve structures thus enabling greater security compared to the techniques performed in interventional fluoroscopy which also have the disadvantage of a large delivery of ionizing radiation for both patient and operator. Several authors have described the main techniques of ultrasound-guided hip intervention and its various applications that can be both diagnostic (as in the case of joint fluid aspiration to assess the presence or absence of septic arthritis) and therapeutic (as in the case of drugs inoculations or evacuation of exceeding intra-articular fluid).
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Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy.

2010

Aims Currently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic gene therapy is also currently incompletely understood. In this study, the effects of increasing doses of adenoviral (Ad) vascular endothelial growth factor-A (VEGF-A) were evaluated on vascular growth, metabolic benefits, and systemic side effects. Methods and results Adenoviral vascular endothelial growth factor-A or AdLacZ control was injected intramuscularly (109–1011 vp/mL) or intra-arterially (5 × 1011 vp/mL) into rabbit ( n = 102) hindlimb muscles and examined 6 or 14 days later. Blood flow, tissue oedema, metabolic benefits, and…

Vascular Endothelial Growth Factor Amedicine.medical_specialtyAngiogenesisGenetic VectorsNeovascularization PhysiologicEnzyme-Linked Immunosorbent Assayta3111Injections IntramuscularAdenoviridaeNeovascularizationchemistry.chemical_compoundInternal medicinemedicineAnimalsMuscle SkeletalUltrasonography InterventionalSprouting angiogenesisDose-Response Relationship Drugbusiness.industryGene Transfer TechniquesMetabolic acidosisGenetic Therapymedicine.diseaseCapillariesHindlimbVascular endothelial growth factorVascular endothelial growth factor AEndocrinologychemistryLac OperonCirculatory systemRabbitsmedicine.symptomCardiology and Cardiovascular MedicinebusinessPerfusionEuropean heart journal
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WhatsAPP in neurosurgery: the best practice is in our hands

2017

WhattsAPPmedicine.medical_specialtymedicine.diagnostic_testbusiness.industrySettore MED/27 - NeurochirurgiaBest practiceMEDLINENeurosurgeryInterventional radiology03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesismedicineSurgeryMedical physicsNeurology (clinical)Neurosurgerybusiness030217 neurology & neurosurgeryNeuroradiology
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Accuracy of ultrasonography in the diagnosis of acute appendicitis in adult patients: review of the literature

2013

Background Ultrasound is a widely used technique in the diagnosis of acute appendicitis; nevertheless, its utilization still remains controversial. Methods The accuracy of the Ultrasound technique in the diagnosis of acute appendicitis in the adult patient, as shown in the literature, was searched for. Results The gold standard for the diagnosis of appendicitis still remains pathologic confirmation after appendectomy. In the published literature, graded-compression Ultrasound has shown an extremely variable diagnostic accuracy in the diagnosis of acute appendicitis (sensitivity range from 44% to 100%; specificity range from 47% to 99% ). This is due to many reasons, including lack of operat…

appendicitisAbdominal painmedicine.medical_specialtyMEDLINEAcuteAcute; appendicitis; ultrasound; abdominal pain; abdomenAbdomen (US)UltrasoundAbdomenmedicineAcute appendicitisRadiological and Ultrasound TechnologyAdult patientsmedicine.diagnostic_testbusiness.industryResearchUltrasoundInterventional radiologyAbdominal PainAcute appendicitis Ultrasound; Abdomen; Abdominal PainAcute appendicitis UltrasoundAcute appendicitisRadiologymedicine.symptomUltrasonographybusinessCritical Ultrasound Journal
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A randomized multicenter trial on a lung ultrasound-guided treatment strategy in patients on chronic hemodialysis with high cardiovascular risk

2021

Lung congestion is a risk factor for all-cause and cardiovascular mortality in patients on chronic hemodialysis, and its estimation by ultrasound may be useful to guide ultrafiltration and drug therapy in this population. In an international, multi-center randomized controlled trial (NCT02310061) we investigated whether a lung ultrasound-guided treatment strategy improved a composite end point (all-cause death, non-fatal myocardial infarction, decompensated heart failure) vs usual care in patients receiving chronic hemodialysis with high cardiovascular risk. Patient-Reported Outcomes (Depression and the Standard Form 36 Quality of Life Questionnaire, SF36) were assessed as secondary outcome…

cardiovascular riskmedicine.medical_specialtymedicine.medical_treatmentPopulationlung congestionlaw.inventionKidney FailureRandomized controlled trialRenal DialysisRisk FactorslawMulticenter trialInternal medicineHumansMedicineChronicRisk factorESRDeducationLungUltrasonography InterventionalDialysisUltrasonographylung ultrasoundeducation.field_of_studyInterventionalbusiness.industryHazard ratiochronic kidney failuremedicine.diseaseESRD; cardiovascular risk; chronic kidney failure; heart failure hemodialysis; lung congestion; lung ultrasoundHeart Disease Risk FactorsCardiovascular DiseasesNephrologyHeart failureQuality of LifeKidney Failure ChronicHemodialysisheart failure hemodialysisbusinessKidney international
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Factors Associated with Decisions for Initial Dosing, Up-Titration of Propiverine and Treatment Outcomes in Overactive Bladder Syndrome Patients in a…

2021

Two doses of propiverine ER (30 and 45 mg/d) are available for the treatment of overactive bladder (OAB) syndrome. We have explored factors associated with the initial dosing choice (allocation bias), the decision to adapt dosing (escalation bias) and how dosing relative to other factors affects treatment outcomes. Data from two non-interventional studies of 1335 and 745 OAB patients, respectively, receiving treatment with propiverine, were analyzed post-hoc. Multivariate analysis was applied to identify factors associated with dosing decisions and treatment outcomes. Several parameters were associated with dose choice, escalation to higher dose or treatment outcomes, but only few exhibited…

dose-titrationmedicine.medical_specialtyMultivariate analysisTreatment outcomeMedizin030232 urology & nephrologyUrologylcsh:MedicineArticle03 medical and health sciencesBasal (phylogenetics)0302 clinical medicinemedicineDosingallocation biasbusiness.industrylcsh:RGeneral Medicinemedicine.diseaseOveractive bladder syndromepropiverineOveractive bladderoveractive bladder syndrome030220 oncology & carcinogenesisNon interventionalPropiverinebusinessmedicine.drugescalation biasJournal of Clinical Medicine
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Pre-operative interventional radiology: could it have a role before complex laparoscopic surgery?

2021

Bleedings occurring during a surgical intervention can be caused by haemostatic defects, but they are generally due to ineffective local haemostasis. Current coagulation systems may not be sufficient to achieve a good haemostasis, causing, at the same time, tissue dama-ge. Furthermore, the availability of such devices does not eliminate difficulties linked to the isolation of vessels, a crucial step of surgical procedures that require the removal of an organ or part of it, in case of inflammation or neoplasm. This difficulty is even more evident, and weighs more on operative times, when the surgeon engages with video-assisted surgery, where anatomical structures are difficult to detect and …

embolic agentsHumansblood loss controlHemorrhageLaparoscopyRadiology InterventionalEmbolization Therapeuticminimally invasive surgery
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