Search results for "Intervertebral Disc"

showing 10 items of 66 documents

A comparative study of mechanical properties of fresh and frozen-thawed porcine intervertebral discs in a bioreactor environment

2016

Abstract Limited availability of fresh intervertebral discs (IVDs) necessitates the use of frozen-thawed samples in biomechanical investigations. Several authors have reported the mechanical properties of frozen-thawed IVDs, but few studies have investigated the effects of storage temperature and cooling rate. The validity and reliability of the applied freezing-thawing procedures are still relatively unknown. The study aims to compare the mechanical responses of fresh porcine IVDs and porcine IVDs, which were frozen at different freezing temperatures with a controlled-rate cooling process and then thawed. The specimens were obtained from pigs aged 6 months. A total of 18 functional spine u…

Cryopreservationmusculoskeletal diseasesLumbar VertebraeMaterials scienceSwine0206 medical engineeringBiomedical EngineeringReproducibility of Results02 engineering and technologymusculoskeletal system020601 biomedical engineeringBiomechanical PhenomenaBiomaterials03 medical and health sciencesBioreactors0302 clinical medicineCooling rateMechanics of MaterialsFreezingBioreactorAnimalsFrozen storageIntervertebral Disc030217 neurology & neurosurgeryBiomedical engineeringJournal of the Mechanical Behavior of Biomedical Materials
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The short-term efficacy and safety of artificial total disc replacement for selected patients with lumbar degenerative disc disease compared with ant…

2018

PurposeTo systematically compare the efficacy and safety of lumbar total disc replacement (TDR) with the efficacy and safety of anterior lumbar interbody fusion (ALIF) for the treatment of lumbar degenerative disc disease (LDDD).MethodsThe electronic databases PubMed, Web of Science and the Cochrane Library were searched for the period from the establishment of the databases to March 2018. The peer-reviewed articles that investigate the safety and efficacy of TDR and ALIF were retrieved under the given search terms. Quality assessment must be done independently by two authors according to each item of criterion. The statistical analyses were performed using RevMan (version 5.3) and Stata (v…

Databases FactualIntervertebral Disc DegenerationCochrane Librarylaw.inventionDatabase and Informatics MethodsMathematical and Statistical Techniques0302 clinical medicineRandomized controlled triallawMedicine and Health SciencesRange of Motion ArticularDatabase Searching030222 orthopedicsMultidisciplinaryQStatisticsRMetaanalysisResearch AssessmentHospitalsTreatment OutcomeResearch DesignMeta-analysisPhysical SciencesObservational StudiesMedicineRange of motionResearch ArticleTotal Disc Replacementmedicine.medical_specialtySystematic ReviewsClinical Research DesignScienceSurgical and Invasive Medical ProceduresResearch and Analysis MethodsDegenerative disc disease03 medical and health sciencesLumbarmedicineHumansStatistical Methodsbusiness.industryEvidence-based medicinemedicine.diseaseSurgeryHealth CareSpinal FusionHealth Care FacilitiesObservational studyAdverse EventsbusinessPublication BiasMathematics030217 neurology & neurosurgeryPLOS ONE
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High-Definition Imaging in Spinal Neuroendoscopy

2010

BACKGROUND Spinal endoscopy is still under controversial discussion. An often acclaimed critic is the poor endoscopic image quality in comparison with the microscope. Since high-definition digital cameras have recently been introduced into spinal neuroendoscopy, the aim of the current study is to examine whether superior image quality has a relevant impact on intraoperativen orientation. MATERIAL AND METHODS A lumbar endoscopic discectomy was recorded simultaneously in High-Definition resolution (HD) and Standard-Definition resolution (SD). 10 experienced spinal surgeons were asked to identify predefined as well as not predefined anatomic structures in HD and SD resolution. Additionally, th…

Endoscopic neurosurgerymedicine.medical_specialtymedicine.diagnostic_testImage qualityOrientation (computer vision)business.industryVideo-Assisted SurgeryGeneral MedicineVideo qualityNeurosurgical ProceduresSurgeryEndoscopyNeuroendoscopyLumbarHumansMedicineHigh definitionSpinal DiseasesSurgeryNeurology (clinical)RadiologybusinessIntervertebral Disc DisplacementDiskectomymin - Minimally Invasive Neurosurgery
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Posterior epidural intervertebral disc migration and sequestration: A systematic review

2022

Posterior epidural intervertebral disc migration and sequestration (PEIMS) is a rare and debilitating complication of degenerative disc disease. Radiological differential diagnosis is often challenging, complicating the accurate planning of appropriate treatment strategies. We systematically reviewed the literature on PEIMS, focusing on clinical-radiological features and available treatments. PubMed, Scopus, Web of Science, and Cochrane were searched to include studies reporting clinical data of patients with PEIMS. Clinical characteristics, treatment strategies, and functional outcomes were analyzed. We included 82 studies comprising 157 patients. Median age was 54 years (range, 19-91). PE…

Epidural SpaceLumbar VertebraeSettore MED/27 - NeurochirurgiaGeneral MedicineIntervertebral Disc DegenerationMiddle AgedSpineSpine surgeryNeurologySettore MED/36Physiology (medical)HumansSurgerySpine fusionNeurology (clinical)Intervertebral DiscDegenerative disc diseaseIntervertebral Disc DisplacementDisc herniation
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Lumbar Disc Degeneration and Sagittal Flexibility

1996

It is uncertain whether intervertebral disc degeneration is associated with reduced or increased flexibility, although lumbar flexibility is known to reduce with advancing age. This cross-sectional study of 214 middle-aged men attempted to determine the influence on lumbar sagittal flexibility from intervertebral disc degeneration parameters measured from magnetic resonance images (disc height, signal intensity, bulging, osteophytes). Multivariate analyses showed that a reduced extent of lumbar flexibility could be accounted for by the combined effect of decreasing disc height together with increasing age, weight, and back pain frequency. Although it remains possible that single degenerate …

Flexibility (anatomy)medicine.diagnostic_testbusiness.industryMagnetic resonance imagingIntervertebral discAnatomyDegeneration (medical)Sagittal planeIntervertebral diskmedicine.anatomical_structureLumbarmedicineBack painSurgeryNeurology (clinical)medicine.symptombusinessJournal of Spinal Disorders
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Prädiktoren der Lebensqualität nach orthopädischer Behandlung lumbaler "bandscheibenbedingter" Rückenschmerzen/ Predictors of quality of life after o…

2003

Zusammenssung Fragestellung: Untersuchung der pradiktiven Bedeutung organpathologischer, psychischer und psychosozialer Parameter fur die Lebensqualitat bei Katamnese von Patienten mit lumbalen "bandscheibenbedingten" Beschwerden. Methode: In dieser prospektiven Studie wurden 109 Patienten mit lumbaler "bandscheibenbedingter" Schmerzsymptomatik vor und ein Jahr nach stationarer orthopadischer Behandlung hinsichtlich ihrer Lebensqualitat und psychischen Belastung untersucht. Der Behandlungserfolg wurde mit Hilfe der deutschen Version des Short Form Health Survey (SF-36), die psychische Belastung mit Hilfe der Symptom-Checkliste 90 (SCL-90-R) und die Krankheitsbewaltigung mit Hilfe des Freibu…

Health related quality of lifeGynecologymedicine.medical_specialtySF-36business.industryOrthopedic surgerymedicineBack painmedicine.symptombusinessLumbar intervertebral discChronic low back painZeitschrift für Psychosomatische Medizin und Psychotherapie
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The Role of Endoscopy in the Treatment of Acute Traumatic Anterior Epidural Hematoma of the Cervical Spine: Case Report

1997

OBJECTIVE AND IMPORTANCE: Epidural hematoma (EDH) of the spine represents an uncommon neurosurgical disorder that sometimes requ;res emergent surgical decompressive therapy. Traumatic EDH of the cervical spine is exceedingly rare. The hematoma is usually located dorsally in the epidural space. We present one case of acute EDH located ventrally in the cervical spine. Special emphasis is placed on the role of spinal endoscopy in surgical treatment. CLINICAL PRESENTATION: After a fall from a tree, a 69-year-old man with rapidly increasing tetraparesis was referred to our institution. Plain films of the cervical spine revealed nothing abnormal. The results of computed tomography were highly sus…

Hematoma Epidural CranialMaleReoperationmedicine.medical_specialtyWounds NonpenetratingHematomaEpidural hematomaSpinal cord compressionmedicineHumansEpidural HemorrhageAgedEndoscopesNeurologic ExaminationForamen magnummedicine.diagnostic_testbusiness.industryDecompression Surgicalmedicine.diseaseEpidural spaceSurgeryEndoscopymedicine.anatomical_structureCervical VertebraeSurgeryNeurology (clinical)EmergenciesbusinessSpinal Cord CompressionIntervertebral Disc DisplacementCervical vertebraeNeurosurgery
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Technical Feasibility of Electromagnetic US/CT Fusion Imaging and Virtual Navigation in the Guidance of Spine Biopsies.

2020

 To test the technical feasibility of electromagnetic computed tomography (CT) + ultrasound fusion (US)-guided bone biopsy of spinal lesions. This retrospective study included 14 patients referred for biopsy of spinal bone lesions without cortical disruption or intervertebral disc infection. Lesions were located in the sacrum (n = 4), lumbar vertebral body (n = 7) or intervertebral disc (n = 3). Fusion technology matched a pre-procedure CT scan with real-time ultrasound. The first six procedures were performed under both standard CT and CT + US fusion guidance (group 1). In the last eight procedures, the needle was positioned under fusion imaging guidance alone, and CT was only used at the …

Image-Guided BiopsyImage fusionmedicine.diagnostic_testbusiness.industryUltrasoundRetrospective cohort studyIntervertebral discSacrum030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicinemedicine.anatomical_structureBone lesion030220 oncology & carcinogenesisBiopsymedicineProcedure DurationFeasibility StudiesHumansRadiology Nuclear Medicine and imagingNuclear medicinebusinessTomography X-Ray ComputedElectromagnetic PhenomenaRetrospective StudiesUltraschall in der Medizin (Stuttgart, Germany : 1980)
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Comparison of 2 Zero-Profile Implants in the Treatment of Single-Level Cervical Spondylotic Myelopathy: A Preliminary Clinical Study of Cervical Disc…

2016

Objectives Cervical disc arthroplasty (CDA) with Discover prosthesis or anterior cervical discectomy and fusion (ACDF) with Zero-P cage has been widely used in the treatment of cervical spondylotic myelopathy (CSM). However, little is known about the comparison of the 2 zero-profile implants in the treatment of single-level CSM. The aim was to compare the clinical outcomes and radiographic parameters of CDA with Discover prosthesis and ACDF with Zero-P cage for the treatment of single-level CSM. Methods A total of 128 consecutive patients who underwent 1-level CDA with Discover prosthesis or ACDF with Zero-P cage for single-level CSM between September 2009 and December 2012 were included in…

MaleKinematicsPhysiologymedicine.medical_treatmentlcsh:MedicineAnterior cervical discectomy and fusionOssificationProsthesisLaryngology0302 clinical medicineMedicine and Health SciencesMedicine030212 general & internal medicineRange of Motion Articularlcsh:ScienceIntervertebral DiscProstheticsMultidisciplinaryPhysicsClassical MechanicsDysphagiaProstheses and ImplantsMiddle Agedmedicine.anatomical_structureTreatment OutcomeConnective TissueSpinal fusionPhysical SciencesCervical VertebraeFemaleBone RemodelingAnatomyRange of motionCervical vertebraeResearch ArticleBiotechnologyDiskectomyAdultmedicine.medical_specialtySurgical and Invasive Medical ProceduresSpinal Cord DiseasesArthroplasty03 medical and health sciencesMusculoskeletal System ProceduresFunctional spinal unitHumansArthroplasty ReplacementLigamentsbusiness.industrylcsh:RBiology and Life SciencesIntervertebral discArthroplastySurgeryBiological TissueSpinal FusionOtorhinolaryngologylcsh:QMedical Devices and EquipmentSpondylosisbusinessPhysiological Processes030217 neurology & neurosurgeryPLoS ONE
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Collagen-low molecular weight hyaluronic acid semi-interpenetrating network loaded with gelatin microspheres for cell and growth factor delivery for …

2015

Intervertebral disc (IVD) degeneration is one of the main causes of low back pain. Current surgical treatments are complex and generally do not fully restore spine mobility. Development of injectable extracellular matrix-based hydrogels offers an opportunity for minimally invasive treatment of IVD degeneration. Here we analyze a specific formulation of collagen-low molecular weight hyaluronic acid (LMW HA) semi-interpenetrating network (semi-IPN) loaded with gelatin microspheres as a potential material for tissue engineering of the inner part of the IVD, the nucleus pulposus (NP). The material displayed a gel-like behavior, it was easily injectable as demonstrated by suitable tests and did …

MaleMaterials scienceBiomedical EngineeringMice SCIDMesenchymal Stem Cell TransplantationBiochemistryChondrocyteInjectionsBiomaterialsExtracellular matrixchemistry.chemical_compoundTransforming Growth Factor beta3Tissue engineeringImplants ExperimentalElastic ModulusHyaluronic acidmedicineAnimalsHumansRegenerationHyaluronic AcidIntervertebral DiscMolecular BiologyMesenchymal stem cellViscosityRegeneration (biology)Mesenchymal stem cellMesenchymal Stem CellsGeneral MedicineChondrocyteChondrogenesisMicrospheresMolecular WeightHydrogelmedicine.anatomical_structurechemistrySelf-healing hydrogelsGelatinCollagenRheologyChondrogenesisBiotechnologyBiomedical engineeringActa biomaterialia
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