Search results for "Intrinsic"
showing 10 items of 386 documents
Bit-Parallel Approximate Pattern Matching on the Xeon Phi Coprocessor
2014
Bit-parallel pattern matching encodes calculated values in bit arrays. This approach gains its efficiency by performing multiple updates within a machine word. An important parameter is therefore the machine word size (e.g. 32 or 64 bits). With the increasing length of vector registers, the efficient mapping of bit-parallel pattern matching algorithms onto modern high performance computing architectures is becoming increasingly important. In this paper, we investigate an efficient implementation of the Wu-Manber approximate pattern matching algorithm on the Intel Xeon Phi coprocessor. This architecture features a 512-bit long vector processing unit (VPU) as well as a large number of process…
SWAPHI-LS: Smith-Waterman Algorithm on Xeon Phi coprocessors for Long DNA Sequences
2014
As an optimal method for sequence alignment, the Smith-Waterman (SW) algorithm is widely used. Unfortunately, this algorithm is computationally demanding, especially for long sequences. This has motivated the investigation of its acceleration on a variety of high-performance computing platforms. However, most work in the literature is only suitable for short sequences. In this paper, we present SWAPHI-LS, the first parallel SW algorithm exploiting emerging Xeon Phi coprocessors to accelerate the alignment of long DNA sequences. In SWAPHI-LS, we have investigated three parallelization approaches (naive, tiled, and distributed) in order to deeply explore the inherent parallelism within Xeon P…
The logic of the construction of rural politics: political discourses on rurality in norway
2009
Two competing discourses emerge from a careful reading of parliamentary debates in Norway on rural development. One regards rural values as intrinsic, while the other regards the rural as an actor ...
Anthropocentrism versus Ecocentrism Revisited: Theoretical Confusions and Practical Conclusions
2013
One of the hardest questions in environmental philosophy is the debate between anthropocentric and ecocentric accounts of value. I argue that a great deal of the disagreement in this debate arises from a) misunderstanding of the concepts used in the debate and b) unfruitful reading of vaguely framed arguments. The conceptual and argumentative analysis of the debate shows that many arguments can be ignored as they either contain conceptual confusion or concern issues that are actually irrelevant to the centrism division. However, there are arguments that maintain their relevance, and these arguments have important consequences on the practical environmental ethics. Hence, contrary to Bryan G…
Motivation and academic performance among first-graders : A person-oriented approach
2016
The present study applies a person-oriented approach to examine the motivational patterns children show on the basis of their reading- and math-related intrinsic value and self-concept of ability and how these patterns are related to their reading and math performance during the first grade of elementary school. The participants were 156 first grade children. The children were examined at the beginning and at the end of their first grade of elementary school. Five groups of children showing differing motivational patterns were identified using the ISOA procedure: Positive, Negative, Math-motivated, Reading-motivated, and Low interest but high belief. Children's motivational patterns were as…
Tracing Curiosity with a Value Perspective
2017
Several have challenged the idea that educating is a neutral endeavour. Following this line of thought, this article intends to examine a common concept often taken for granted: curiosity. The aim of the article is to show how curiosity is constructed as a value-loaded notion by tracing its understandings in an early-childhood-education-and-care (ECEC) context from a value perspective. Four official ECEC documents from different organisational levels will be analysed. Informed by qualitative content analysis with a concept-driven strategy, the document analysis seeks to establish connections between the notion of curiosity and prominent value fields in ECEC, such as competence, democracy an…
Motivations and domain specificity in intercultural adaptation : bloggers' experiences in their new host countries
2014
The current qualitative study investigates immigrant’s intrinsic (internal) and extrinsic (external) motivations and how they surface in the intercultural adaption process. Additionally, it aims to answer whether immigrant’s adaptation orientations differ between private and public (life) domains by testing Boski’s (2008) IAFS model [the model of integration as functional(partial) specialization]. It is a fairly recent model of adaptation and only few prior studies have utilized it. The study concentrates on voluntary migrants, individuals, who have made a personal choice to leave their homelands. In the current study naturally occurring data in a form of weblogs were utilized as research d…
Gastric cancer in autoimmune gastritis: A case-control study from the German centers of the staR project on gastric cancer research
2020
Objectives Patients with autoimmune gastritis (AIG) are reported to have an increased risk of developing gastric cancer (GC). In this study, we assess the characteristics and outcomes of GC patients with AIG in a multicenter case-control study. Methods Between April 2013 and May 2017, patients with GC, including cancers of the esophagogastric junction (EGJ) Siewert type II and III, were recruited. Patients with histological characteristics of AIG were identified and matched in a 1:2 fashion for age and gender to GC patients with no AIG. Presenting symptoms were documented using a self-administered questionnaire. Results Histological assessment of gastric mucosa was available for 572/759 GC …
Objective Bayesian point and region estimation in location-scale models.
2007
Point and region estimation may both be described as specific decision problems. In point estimation, the action space is the set of possible values of the quantity on interest; in region estimation, the action space is the set of its possible credible regions. Foundations dictate that the solution to these decision problems must depend on both the utility function and the prior distribution. Estimators intended for general use should surely be invariant under one-to-one transformations, and this requires the use of an invariant loss function; moreover, an objective solution requires the use of a prior which does not introduce subjective elements. The combined use of an invariant informatio…
Pharmacodynamic approach to study the gene transfer process employing non-viral vectors
2000
Abstract In the present work we set out to apply pharmacodynamic concepts derived from dose–response curves (Potency and Efficacy) to characterize the gene transfer efficiency of a vector:DNA complex. We employed two widely used vectors, the cationic lipid DOTAP (N,N,N-trimethyl 1-2-3-bis (1-oxo-9-octa-decenyl)oxy-(Z,Z)-1-propanaminium methyl sulfate) and the cationic polymer PEI (polyethylenimine, 800 kDa) to transfect several constructions of the green fluorescent protein cDNA. The analysis of dose–response curves indicated that in all cases the goodness-of-fit was > 0.99. Potency is a measure that provides information on gene activity per amount of DNA. Efficacy is a measure of maximum g…