Search results for "Iode"

Sacrifices d'animaux, traditions gauloises et influences romaines

2002

International audience; En Gaule, des sacrifices animaux sont probablement pratiqués dans des sanctuaires, des nécropoles, mais sans doute dans d'autres contextes à l'occasion de banquets, par exemple2. À ces divers lieux et circonstances correspondent probablement diverses motivations et finalités. Au début de notre ère, les sacrifices animaux subissent probablement l'influence romaine, mais les sites permettant de juger de cette éventuelle influence sont encore peu nombreux. En effet, les lieux où des sacrifices animaux sont bien attestés, comme à Gournay-sur-Aronde et Vertault, sont rares et éloignés les uns des autres, aussi bien dans l'espace que dans le temps. À côté de cela, les sanc…

New polysaccharide-polyaminoacid hydrogels: a suitable strategy for colon-specific drug delivery

2007

The aim of this study was to prepare and characterize novel hydrogels with polysaccharide–polyaminoacid structure, able to undergo an enzymatic hydrolysis in the colon and potentially useful for treating inflammatory bowel diseases (IBD). Starting materials were methacrylated dextran (DEX-MA) and methacrylated α,β-poly(N-2-hydroxyethyl)-DL-aspartamide (PHM). These polymers were photocrosslinked by exposure of their aqueous solutions at 313 nm without photoinitiators. Different samples, shaped as microparticles, were obtained as a function of polymer concentration and irradiation time. FT-IR analysis confirmed the occurrence of a co-crosslinking between DEX-MA and PHM in all experimental con…

EVALUATION OF BIODEGRADABILITY ON POLYSPARTAMIDE-POLYLACTIC ACID BASED NANOPARTICLES BY CHEMICAL HYDROLYSIS STUDIES POLYMER DEGRADATION AND STABILITY

2015

Here, the synthesis of two graft copolymers based on α,β-poly(N-2-hydroxyethyl)-D,L-aspartamide (PHEA) and poly(lactic acid) (PLA), the O-(2-aminoethyl)-O′-galactosyl polyethylene glycol (GAL-PEG-NH2) or the methoxypolyethylene glycol amine (H2N-PEG-OCH3) is described. Starting from the obtained PHEA-PLA-PEG-GAL and PHEA-PLA-PEG copolymers, polymeric nanoparticles were prepared by high pressure homogenization–solvent evaporation method. To demonstrate their biodegradability as a function of the matrix composition, a chemical stability study was carried out until 21 days by incubating systems in two media mimicking physiological compartments (pH 7.4 and pH 5.5). The degradability of both nan…

Evaluation of biodegradability of novel polymeric nanoparticles based on amphiphilic polylactide-polyaspartamide derivatives.

2015