Search results for "Istologia"
showing 10 items of 140 documents
Analisi delle varianti rare del carcinoma a cellule uroteliali della vescica nei Pazienti sottoposti a cistectomia radicale: impatto sulla prognosi.
2013
The association between appendicitis severity and patient age with appendiceal neoplasm histology—a population-based study
2022
Abstract Purpose Recent studies have reported alarming appendiceal tumor rates associated with complicated acute appendicitis, especially in patients presenting with a periappendicular abscess. However, the data on histology of appendiceal tumors among acute appendicitis patients is limited, especially in patient cohorts differentiating between uncomplicated and complicated acute appendicitis. We have previously reported the association of increased appendiceal tumor prevalence with complicated acute appendicitis in this population-based study. The objective of this secondary analysis was to evaluate the association of both appendicitis severity and patient age with appendiceal tumor histol…
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
2016
Seuls les 100 premiers auteurs dont les auteurs INRA ont été entrés dans la notice. La liste complète des auteurs et de leurs affiliations est accessible sur la publication.; International audience; In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues…
Autophagy
2012
Klionsky, Daniel J. et al.
The effects of dietary fumonisin B1 on growth and physiology of rainbow trout (Oncorhynchus mykiss)
2016
Kalanrehuissa on perinteisesti luotettu kalajauhoon ja -öljyyn rehujen pääasiallisina proteiinin- ja energianlähteinä. Näitä raaka-aineita on nykyään alettu korvata kasviperäisillä ainesosilla niiden edullisemman hinnan ja helpomman saatavuuden vuoksi, esimerkiksi maissilla, vehnällä ja soijalla. Pilaantuneen kasviperäisen raaka-aineen mukana rehuun pääsee haitallisia mykotoksiineja. Mykotoksiinit ovat homesienten sekundäärisiä metaboliatuotteita, joita ne pääasiassa tuottavat kilpailuun muita homeita vastaan, ja joiden on havaittu aiheuttavan kasvun heikentymistä ja sairauksia monilla eri kotieläimillä, mutta niiden vaikutuksista kaloihin tiedetään varsin vähän. Yksi yleisimmistä mykotoksi…
Autophagy
2021
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide…
CHARACTERIZATION AND ENERGETIC METABOLISM ANALYSIS OF DIFFERENT POPULATIONS OF UMBILICAL CORD MESENCHYMAL STEM CELLS FOR THE TREATMENT OF STROKE
Stroke is a leading cause of death and disability worldwide. A direct consequence of oxygen and glucose deprivation during stroke is the dysfunction of mitochondria that impairs oxidative metabolism and contributes to oxidative stress, neuronal death and inflammation. Human umbilical cord (UC)-derived MSCs (UC-MSCs) are an attractive source for regenerative medicine purposes due to their self-renewal and multipotent differentiation potential, immunomodulatory and anti-inflammatory abilities. Notably, because UC is supplied from only three blood vessels, the UC-MSCs are physiologically adapted to survive in a relatively hypoxic and glucose poor environment leading to the hypothesis that thes…
Fyysisen aktiivisuuden yhteys rintasyövän erilaistumisasteeseen postmenopausaalisilla naisilla
2015
Rintasyöpä on naisten yleisin syöpä länsimaissa ja eniten sitä esiintyy yli 60-vuotiailla. Postmenopausaalisen rintasyövän riskiin voidaan vaikuttaa fyysisen aktiivisuuden avulla. Fyysisen aktiivisuuden on aikaisemmissa tutkimuksissa todettu olevan yhteydessä rintasyöpäriskiin siten, että liikuntaa harrastavilla rintasyöpäriski on pienempi kuin vähän liikkuvilla. Tämän työn tarkoituksena oli selvittää, onko fyysinen aktiivisuus yhteydessä rintasyövän histologiseen erilaistumisasteeseen postmenopausaalisilla naisilla. Lisäksi tutkittiin, mitkä muut tekijät ovat yhteydessä rintasyövän histologiseen erilaistumisasteeseen. Tämän poikkileikkaustutkimuksen aineistona on käytetty 12 kuukautta kest…
Juutalainen Jeesus
2013
H&E Multi-Laboratory Staining Variance Exploration with Machine Learning
2022
In diagnostic histopathology, hematoxylin and eosin (H&E) staining is a critical process that highlights salient histological features. Staining results vary between laboratories regardless of the histopathological task, although the method does not change. This variance can impair the accuracy of algorithms and histopathologists’ time-to-insight. Investigating this variance can help calibrate stain normalization tasks to reverse this negative potential. With machine learning, this study evaluated the staining variance between different laboratories on three tissue types. We received H&E-stained slides from 66 different laboratories. Each slide contained kidney, skin, and colon tissue sampl…