Search results for "Itching"
showing 10 items of 316 documents
"Me ollaan mukana tässä experimentissä" : lingvististiska resurser och språkpraktiker i tvåspråkiga ungdomssamtal i Haparanda, Stockholm och Helsingf…
2017
The thesis explores bilingual adolescents’ language use, linguistic resources, and language practices in interaction at three junior high schools in Haparanda, a Swedish town on the country’s northeastern border with Finland. A comparison is also made with interaction among bilingual adolescents at two Sweden-Finnish junior high schools in Stockholm and at one Swedish-speaking junior high school in Helsinki. The aim of the study is to increase our knowledge of bilingual adolescents’ interaction practices and language repertoires, i.e. translanguaging, in interaction. The primary data consists of close to eleven hours of video- and audio-recorded informal group and pair conversations. The da…
Groupware architecture for requirements processes in new product development
1999
An organization's ability to create successful products depends on how extensively it collects, analyzes and utilizes requirements information in its product development. Recent advances in groupware technologies allow such information to be shared more effectively in distributed organizations; thus, these technologies hold considerable potential as means of shortening the cycle time and improving the quality of requirements processes. This paper addresses issues in the design and implementation of groupware-supported requirements processes by drawing on experiences from large-scale industrial development projects within Nokia. The primary contribution of the paper is the conceptual design …
Supercontinuum Generation and Intermodal Four-Wave Mixing in a Step-Index Few-Mode Fibre
2019
International audience; The complex spatiotemporal dynamics of nonlinear light propagation in multimode fibers (MMFs) has recently witnessed a renewed interest because of their experimental realization in emerging key areas of laser physics and fiber optics [1]. Specifically, MMFs have a number of linear and nonlinear optical properties that make them very attractive to investigate new spatiotemporal effects fundamentally different from standard single-mode fibers. These include the observation of multimode solitons [2], intermodal four-wave mixing (FWM) [3], geometric parametric instabilities [4], spatial beam self-cleaning [5], and the generation of supercontinuum (SC) light when pumping …
Benefits and Drawbacks of A High Frequency Gan Zvzcps Converter
2017
This paper presents the benefits and drawbacks of replacing the traditional Si Mosfets transistors with enhancement mode GaN transistors in a Half-Bridge Zero Voltage and Zero Current Switching Power Switching (ZVZCPS) converter. This type of converters is usually used as Electronic Power Converters (EPC) for telecommunication satellites travelling-wave tube amplifiers (TWTAs). In this study, firstly the converter is theoretically analysed, obtaining its operation, losses and efficiency equations. From these equations, optimizations maps based on the main system parameters are obtained. These optimization maps are the key to quantify the potential benefits of GaN transistors in this type of…
Changes in ocular signs and symptoms when switching from preserved latanoprost 0.005% to preservative-free tafluprost 0.0015%: phase IIIb study in pa…
2008
Purpose This open-label, multinational, phase IIIb study investigated the changes in ocular signs and symptoms when patients were switched from preserved latanoprost 0.005% to preservative-free tafluprost 0.0015% (q.d. at 20:00) for 12 weeks. Methods Patients with open-angle glaucoma or ocular hypertension who had received latanoprost for at least 6 months and had at least 2 ocular symptoms or one symptom and one sign were enrolled (n=158). Change from screening in ocular symptoms and signs were the main endpoints. Data from the 6-week analysis are reported here. Results After switching to preservative-free tafluprost, the proportion of patients with at least mild symptoms decreased: irrita…
Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle
2012
Abstract Background The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a master regulator of energy metabolism, coactivates in cell lines pyruvate dehydrogenase kinase-4 (PDK4) gene expression via the estrogen-related receptor α (ERRα). We investigated the effects of long-term high-fat diet and physical activity on the expression of PDK4, PGC-1α and ERRα and the amount and function of mitochondria in skeletal muscle. Methods Insulin resistance was induced by a high-fat (HF) d…
Vulvo-vaginal atrophy: A new treatment modality using thermo-ablative fractional CO2 laser.
2015
a b s t r a c t Objective: To evaluate the efficacy and feasibility of thermo-ablative fractional CO2 laser for the treatment of symptoms related to vulvo-vaginal atrophy (VVA) in post-menopausal women. Methods: From April 2013 to December 2013, post-menopausal patients who complained of one or more VVA-related symptoms and who underwent vaginal treatment with fractional CO2 laser were enrolled in the study. At baseline (T0) and 30 days post-treatment (T1), vaginal status of the women was evaluated using the Vaginal Health Index (VHI), and subjective intensity of VVA symptoms was evaluated using a visual analog scale (VAS). At T1, treatment satisfaction was evaluated using a 5-point Likert …
A Multiple Surrogate Assisted Decomposition Based Evolutionary Algorithm for Expensive Multi/Many-Objective Optimization
2019
Many-objective optimization problems (MaOPs) contain four or more conflicting objectives to be optimized. A number of efficient decomposition-based evolutionary algorithms have been developed in the recent years to solve them. However, computationally expensive MaOPs have been scarcely investigated. Typically, surrogate-assisted methods have been used in the literature to tackle computationally expensive problems, but such studies have largely focused on problems with 1–3 objectives. In this paper, we present an approach called hybrid surrogate-assisted many-objective evolutionary algorithm to solve computationally expensive MaOPs. The key features of the approach include: 1) the use of mul…
Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle
2012
Background. The expression of PDK4 is elevated by diabetes, fasting and other conditions associated with the switch from the utilization of glucose to fatty acids as an energy source. It is previously shown that peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), a master regulator of energy metabolism, coactivates in cell lines pyruvate dehydrogenase kinase-4 (PDK4) gene expression via the estrogen-related receptor α (ERRα). We investigated the effects of long-term high-fat diet and physical activity on the expression of PDK4, PGC-1α and ERRα and the amount and function of mitochondria in skeletal muscle. Methods. Insulin resistance was induced by a high-fat (HF) diet for…
Design and realization of a DC/DC converter with a partially saturated inductor
2017
DC/DC converters, in some types of applications such as portable equipments, can require more space than it is actually available. The inductor is typically the most bulky element and the possibility to reduce its size can save up to 50% of the converter volume and area [1][2], thus increasing the power density. This reduction, however, comes with nonlinear effects caused by the saturation of the ferromagnetic core. An appropriate modelling of the inductor and of the converter circuit is needed for guaranteeing a good output power quality (Fig. 1). A Boost converter with an inductor in the partially saturated roll-off operating zone was designed and realized to study the behaviour of DC/DC …