Search results for "JUNCTION"
showing 10 items of 862 documents
Neuromuscular fatigue following high versus low-intensity eccentric exercise of biceps brachii muscle
2009
International audience; Purpose: This study investigated neuromuscular fatigue following high versus low-intensity eccentric exercise corresponding to the same amount of work.Methods: Ten volunteers performed two eccentric exercises of the elbow flexors: a high-intensity versus a low-intensity exercise. Maximal voluntary contraction torque and surface electromyography of the biceps brachii muscle were recorded before, immediately and 48 h after exercises. Maximal voluntary activation level, neural (M-wave) and contractile (muscular twitch) properties of the biceps brachii muscle were analysed using electrical stimulation techniques.Results: Maximal voluntary contraction torque was significa…
Neuromuscular fatigue and recovery in male and female athletes during heavy resistance exercise.
1993
To examine neuromuscular fatigue and recovery ten male and nine female athletes performed a strenuous heavy resistance exercise protocol. The subjects strained their leg extensor muscles with the same maximal relative intensity by performing one maximal squat-lift with a load of 100% of 1 RM (one repetition maximum) 20 times (20 x 1 x 100%). Maximal voluntary neural activation (integrated EMG), maximal bilateral isometric force, force-time and relaxation-time curves of the leg extensor muscles were measured before and immediately after the exercise session as well as after resting for 1 hour, 2 hours, 1 day and 2 days. The session resulted in considerable gradual decreases in maximal force …
Daily hormonal and neuromuscular responses to intensive strength training in 1 week.
1988
Daily adaptive responses in the neuromuscular and endocrine systems to a 1-week very intensive strength training period with two training sessions per day were investigated in eight elite weight lifters. The morning and the afternoon sessions resulted in acute decreases (P less than 0.05-0.01) in maximal isometric strength and in the maximal neural activation (iEMG) of the leg extensor muscles, but the basic levels remained unaltered during the entire training period. Significant (P less than 0.05-0.01) acute increases in serum total and free testosterone levels were found during the afternoon sessions. During the 1-week training period, serum total and free testosterone concentrations decr…
Effect of electrostimulation training-detraining on neuromuscular fatigue mechanisms.
2007
The aim of this study was to evaluate the effects of neuromuscular electrical stimulation (NMES) training and subsequent detraining on neuromuscular fatigue mechanisms. Ten young healthy men completed one NMES fatigue protocol before and after a NMES training program of 4 weeks and again after 4 weeks of detraining. Muscle fatigue (maximal voluntary torque loss), central fatigue (activation failure), and peripheral fatigue (transmission failure and contractile failure) of the plantar flexor muscles were assessed by using a series of electrically evoked and voluntary contractions with concomitant electromyographic and torque recordings. At baseline, maximal voluntary torque decreased signifi…
Clinical practice guidelines: Oral health care for children and adults living with epidermolysis bullosa.
2020
Background Inherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility and unique oral features. Aims To provide (a) a complete review of the oral manifestations in those living with each type of inherited EB, (b) the current best practices for managing oral health care of people living with EB, (c) the current best practices on dental implant-based oral rehabilitation for patients with recessive dystrophic EB (RDEB), and (d) the current best practice for managing local anesthesia, principles of sedation, and general anesthesia for children and adults with EB undergoing dental treatment. Methods Systematic literature search, panel discussion including clinical…
A quantitative study of the pancuronium antagonism at the motor endplate in human organophosphorus intoxication
1995
Nine patients with organophosphorus (OP) intoxication developing neuromuscular transmission defects were given pancuronium 1, 2, or 4 mg intravenously (IV). Thirteen patient controls with hypoxic encephalopathy received similar dosages. The responses were monitored electrophysiologically using single and repetitive nerve stimulation (20 and 50 Hz). In OP patients, pancuronium did not alter the amplitude of the single CMAP, whereas its repetitive discharges were reduced. Severe neuromuscular blocks were reversed only partially by pancuronium 4 mg. In less severe blocks, 1 and 2 mg resulted in marked improvement. In the patient controls, pancuronium 4 mg induced a severe neuromuscular block b…
Myofibroblasts Are Evidence of Chronic Tissue Microtrauma at the Endometrial-Myometrial Junctional Zone in Uteri With Adenomyosis.
2017
Background Adenomyosis (AM) uteri exhibit hyperperistalsis. The latter causes a chronic tissue trauma at the endometrial-myometrial junctional zone (EMJZ). Upon tissue trauma, microdehiscences in the myometrium facilitate the translocation of basal endometrial fragments into the myometrium. There, a metaplasia (mediated by transforming growth factor β1 [TGFβ1] and connective tissue growth factor [CTGF]) occurs and AM lesions develop. The abundance of myofibroblasts in a tissue hallmarks metaplasia and points to a tissue microtrauma. Materials and methods To study if myofibroblasts-as an evidence of tissue microtrauma-are more abundant at EMJZ in AM-uteri, a case-control experimental study w…
Is abdominal compression a useful stimulation test for analysis of lower esophageal sphincter function?
1984
The change in pressure of competent and incompetent lower esophageal sphincter (LES) due to abdominal compression is still a controversial subject. Therefore, we studied the effect of sustained (SAC) and intermittent (IAC) abdominal compression on lower esophageal sphincter pressure (LESP) in normals (N), patients with hiatus hernia (HH), and patients with scleroderma (S). When resting lower esophageal sphincter pressure exceeded 15 mm Hg, response to SAC and IAC was similar in patients with HH and in normals. On the other hand when basal LESP was below 15 mm Hg, stimulated sphincter pressure during IAC was significantly lower than during SAC. Values recorded during SAC were also falsely hi…
Esophageal transmural potential difference in patients with symptomatic gastroesophageal reflux.
1980
Esophageal electrical potential difference (PD) was studied in 9 patients with symptomatic gastroesophageal reflux and in 9 healthy control subjects. None of the patients revealed gross mucosal damage by radiography or endoscopy, but all of them showed positive acid perfusion studies. In the stomach and across the lower esophageal sphincter PD profiles were remarkably similar in patients and controls. Throughout the lower esophagus however, PD values were slightly higher in patients with symptomatic reflux than in healthy volunteers. These data are in contrast to a previous investigation, in which patients with reflux-induced gross mucosal damage revealed a decreased PD in the lower esophag…
Neuromuscular adaptations and serum hormones in females during prolonged power training.
1990
Training-induced adaptations in the neuromuscular and endocrine systems were investigated in seven females during prolonged power type strength training. Great (p less than 0.05) changes occurred primarily during the earlier weeks of the 16-week training especially in the time of force production (from 161 +/- 107 to 93 +/- 65 ms to produce a 500 N force) and, correspondingly, in the average forces in the earlier positions of the (absolute) force-time curve of the leg extensor muscles. These changes were accompanied by significant (p less than 0.05) increases in the neural activation of the trained muscles in the earliest positions of the IEMG-time curve. Hypertrophic changes, as judged fro…