Search results for "JUNCTION"
showing 10 items of 862 documents
PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion.
2015
Abstract Correct apicobasal polarization and intercellular adhesions are essential for the appropriate development of normal epithelia. Here, we investigated the contribution of the cell polarity regulator PARD3 to the development of lung squamous cell carcinomas (LSCC). Tumor-specific PARD3 alterations were found in 8% of LSCCs examined, placing PARD3 among the most common tumor suppressor genes in this malignancy. Most PAR3-mutant proteins exhibited a relative reduction in the ability to mediate formation of tight junctions and actin-based protrusions, bind atypical protein kinase C, activate RAC1, and activate STAT3 at cell confluence. Thus, PARD3 alterations prevented the formation of c…
Sakārtojuma saikļi dažādu reģistru tekstu saliktos sakārtotos teikumos
2017
Šajā pētījumā tiek analizēti sakārtojuma saikļi saliktos sakārtotos teikumos Britu Nacionālajā Korpusā. Pētījuma mērķis ir izpētīt sakārtojuma saikļu, kas saista neatkarīgas teikuma daļas saliktos sakārtotos teikumos tekstos, kas sagrupēti četros dažādos reģistros (akadēmiski teksti, daiļliteratūra, laikraksti un sarunas) Britu Nacionālajā Korpusā, biežumu un dažādību. Teorētiskā pētījuma metode, kas tika izmantota, ir teoriju par sakārtojuma saikļiem, saliktiem sakārtotiem teikumiem, reģistru un korpusu salīdzināšana. Sekojošas kvantitatīvās pētījuma metodes tika izmantotas – pirmkārt, saliktu sakārtotu teikumu ieguve no korpusa, pēc tam tika izmantotas tādas aprakstošās statistikas metode…
Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering.
2006
The establishment of a functional vasculature is as yet an unrealized milestone in bone reconstruction therapy. For this study, fiber-mesh scaffolds obtained from a blend of starch and poly(caprolactone) (SPCL), that have previously been shown to be an excellent material for the proliferation and differentiation of bone marrow cells and thereby represent great potential as constructs for bone regeneration, were examined for endothelial cell (EC) compatibility. To be successfully applied in vivo, this tissue engineered construct should also be able to support the growth of ECs in order to facilitate vascularization and therefore assure the viability of the construct upon implantation. The ma…
Las inteligencias múltiples en la escuela
2002
During many years has prevailed the idea of intelligence as a single problem solving ability (factor g) considered the best predictor of student’s academic achievement. Recently, researches have begun to take an alternative view of the problem, understanding it is a multidimensional construct. Multiple intelligences (MI) theory proposed by Gardner (1983) takes into account seven talents or skills individuals appear to have in certain amount. These latent bio-psychological potentials are stable and they are mantained through life. Theory of MI proposes that every person learns in relation to them. MI theory has many educational applications, however, very few efforts have been made to verify…
Modifications électrochimiques de surfaces et dispositifs électroniques organiques
2018
Organic electronics remains a fruitful research field thanks to the diversity of molecular structures reachable by organic synthesis. Molecular materials offer convenient shaping processes, such as solution processing techniques, which can be used for the fabrication of organic devices on plastic substrates.Our works can be summarized as the elaboration of conductometric devices thanks to electrochemistry and the study of their electrical and sensing properties. They deal with two topics: the development of new transducers based on substituted polyanilines and phthalocyanines and the study of the influence of electrochemical modifications on the behavior of known devices.We first developped…
Comparative analysis of the structure of temporomandibular joint in human and rabbit.
2016
In order to increase knowledge on the morphology and structure of the articular disc of the temporomandibular joint (TMJ) for a better understanding of the functional role of the same, it proceeded with an investigation on histological samples in the block of TMJ and periarticular tissues of adult rabits and human fatustes at different stage of development. (www.actabiomedica.it)
LIQUIDI IONICI E FULLERENI: PIATTAFORME PER NUOVI MATERIALI
The synthesis of innovative catalysts based on different carbon nanoforms (CNFs), namely fullerene C60 and carbon nanotubes (CNTs), and their application in Suzuki and Heck C-C coupling reactions, constitutes the common thread of the first part (Chapter 1 and 2) of this thesis. C60 and CNTs were functionalized with ionic liquids (ILs) and poly-amidoamine (PAMAM) dendrimers, respectively, and used as supports for palladium nanoparticles (PdNPs). Moreover, additional supported catalytic systems based on one of the synthesized C60-IL hybrids were prepared and successfully employed in the title coupling reactions. The final part (Chapter 3) of the thesis deals on the microwave-mediated synthesi…
Preparation and photocatalytic activity of ZnO-SnO2, ZnO-ZnWO4 and SnO2-ZnO-ZnWO4 nanocomposites
2014
Josephson-junction-based axion detection through resonant activation
2022
We discuss the resonant activation phenomenon on a Josephson junction due to the coupling of the Josephson system with axions. We show how such an effect can be exploited for axion detection. A nonmonotonic behavior, with a minimum, of the mean switching time from the superconducting to the resistive state versus the ratio of the axion energy and the Josephson plasma energy is found. We demonstrate how variations in switching times make it possible to detect the presence of the axion field. An experimental protocol for observing axions through their coupling with a Josephson system is proposed.
Generation of travelling sine-Gordon breathers in noisy long Josephson junctions
2022
The generation of travelling sine-Gordon breathers is achieved through the nonlinear supratransmission effect in a magnetically driven long Josephson junction, in the presence of losses, a current bias, and a thermal noise source. We demonstrate how to exclusively induce breather modes by means of controlled magnetic pulses. A nonmonotonic behavior of the breather-only generation probability is observed as a function of the noise intensity. An experimental protocol providing evidence of the Josephson breather's existence is proposed.