Search results for "Jawbones"

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Nonexposed Variant of Bisphosphonate-associated Osteonecrosis of the Jaw: A Case Series

2010

Abstract Purpose To report a case series of patients with the nonexposed variant of bisphosphonate-associated osteonecrosis of the jaw—a form of jaw osteonecrosis that does not manifest with necrotic bone exposure/mucosal fenestration. Methods Among 332 individuals referred to 5 clinical centers in Europe because of development of jawbone abnormalities after or during exposure to bisphosphonates, we identified a total of 96 patients who presented with the nonexposed variant of osteonecrosis. Relevant data were obtained via clinical notes; radiological investigations; patients' history, and referral letters. Results The most common clinical feature of nonexposed osteonecrosis was jaw bone pa…

OsteochemonecrosisMaleTime FactorsAvascular necrosisMandibleAvascular necrosiEpidemiologyMaxillaProspective cohort studyMultiple myelomaAged 80 and overeducation.field_of_studyAlendronateBone Density Conservation AgentsDiphosphonatesOsteochemonecrosiOsteonecrosisGeneral MedicineBisphosphonatesMiddle AgedKidney NeoplasmsEuropeAvascular necrosisFemaleMultiple MyelomaAdultmedicine.medical_specialtyPopulationJawsBreast NeoplasmsSettore MED/28 - Malattie OdontostomatologicheJawbonesmedicineHumansBisphosphonateeducationAgedBisphosphonate-associated osteonecrosis of the jawbusiness.industryProstatic NeoplasmsAvascular necrosis; Bisphosphonates; Jawbones; Jaws; Mandible; Maxilla; Osteochemonecrosis; Osteonecrosismedicine.diseaseDermatologySurgeryJawMaxillaOsteoporosisJawbonebusinessOsteonecrosis of the jawJaw Diseases
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Up to a quarter of patients with osteonecrosis of the jaw associated with antiresorptive agents remain undiagnosed

2014

AbstractRecent data suggest that the traditional definition of bisphosphonate-associated osteonecrosis of the jaw (ONJ) may exclude patients who present with the non-exposed variant of the condition. To test the hypothesis that a proportion of patients with ONJ remain undiagnosed because their symptoms do not conform to the traditional case definition, we did a secondary analysis of data from MISSION (Multicentre study on phenotype, definition and classification of osteonecrosis of the jaws associated with bisphosphonates), a cross-sectional study of a large population of patients with bisphosphonate-associated ONJ who were recruited in 13 European centres. Patients with exposed and non-exp…

MaleDelayed DiagnosisSettore MED/50 - Scienze Tecniche Mediche ApplicateAntineoplastic AgentsOsteonecrosis; Jawbones; BisphosphonatesOsteonecrosis; Jawbones;BisphosphonatesSettore MED/29 - Chirurgia MaxillofaccialeSettore MED/28 - Malattie OdontostomatologicheOsteonecrosis; Jawbones; Bisphosphonates;JawbonesBisphosphonateHumansDiagnostic Errorsosteonecrosis; jawbones; bisphosphonatesPeriodontal DiseasesAgedPain MeasurementBone Density Conservation AgentsOsteonecrosisBisphosphonatesMiddle AgedCross-Sectional StudiesPhenotypeOtorhinolaryngologyTooth DiseasesTooth ExtractionOsteonecrosiOsteoporosisSurgeryBisphosphonate-Associated Osteonecrosis of the JawFemaleOral SurgeryJawbone
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