Search results for "Joints"

Presenza di Osteoartrite in un campione scheletrico proveniente da una necropoli paleocristiana di Marsala (Italia)

2008

Traditional vs. sliding-joint masonry infilled frames: Seismic reliability and EAL

2020

Abstract In reinforced concrete (RC) multi-storey buildings, the important role of the seismic interaction of structural frames with masonry infills has been revealed by several earthquakes and investigated by many authors. Recently, several innovative infill solutions have been proposed to mitigate such interaction, which could result in widespread damage in both the masonry and the RC structure and sometimes jeopardize the building stability and the occupants’ safety. One solution consists in the partitioning of the masonry infill into several sub-panels, relatively sliding along specific joints. This paper investigates the seismic assessment of this technological solution in the framewor…

Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells

2021

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.sciencedirect.com/science/article/pii/S2214031X21000656?via%3Dihub Background: Osteoarthritis (OA) is a joint disease characterized by cartilage degradation, low-grade synovitis and subchondral bone alterations. In the damaged joint, there is a progressive increase of oxidative stress leading to disruption of chondrocyte homeostasis. The modulation of oxidative stress could control the expression of inflammatory and catabolic mediators involved in OA. We have previously demonstrated that extracellular vesicles (EVs) present in the secretome of human mesenchymal stem cells from adipose tissu…

Influence of material characteristics on plastomechanics of the fsw process for T-joints

2009

Abstract The potential of friction stir welding (FSW) has thoroughly been investigated by several authors, however their focus has primarily been on butt joints. T-joints are of paramount interest for transportation industries especially due to their capacity to straighten panels. Welding of T-joints is very challenging due to thin walls, poor location of the rib–web interface and the requirements for corner-fillets. This paper investigates FSW of T-joints of two popular aluminum alloys, i.e. 2024-T4 and 6082-T6, and the role played by the material characteristics on joining. First, an experimental study is carried out with specially designed fixture to determine the effect of process condi…

Design and use of a Fatigue Test Machine in Plane Bending for Composite Specimens and Bonded Joints

2011

Polymeric and composites materials are increasingly used in industry as structural parts, so that specific information on their mechanical properties "at long term" (creep, relaxation, fatigue) are requested. The design and implementation of these components also requires that they are permanently connected together to perform certain functions. The use of adhesives in structural joints has increased over recent years thanks to the continuous development by companies which provide the market with adhesive having better and better mechanical properties. The main areas relate to the aerospace, aeronautical and automotive industries, where requirements are required for lightness and reliabilit…

TOWARD A DESIGN METHOD FOR METAL-COMPOSITE CO-CURED JOINT BASED ON THE G-SIFs

2013

Abstract In this work, a systematic study of the singular stress field in the zone where the interface intersects the free edge surfaces of bonded metal-composite co-cured joints, has been performed. The obtained theoretical, numerical and experimental results have permitted to detect the relationships between the joint configuration and the singular stress field, as well as to implement a new design method based on the so called generalised stress intensity factors. Such a proposed method allows the user to predict the static strength of a generic metal-composite co-cured joint, vs. the main influence parameters as the elastic modulus of the coupled materials, the overlap length, the taper…

Summary and recommendations of the OARSI FDA osteoarthritis Assessment of Structural Change Working Group

2011

Import JabRef | WosArea Orthopedics; Rheumatology; International audience; Objective: The Osteoarthritis Research Society International initiated a number of working groups to address a call from the US Food and Drug Administration (FDA) on updating draft guidance on conduct of osteoarthritis (OA) clinical trials. The development of disease-modifying osteoarthritis drugs (DMOADs) remains challenging. The Assessment of Structural Change (ASC) Working Group aimed to provide a state-of-the-art critical update on imaging tools for OA clinical trials. Methods: The Group focussed on the performance metrics of conventional radiographs (CR) and magnetic resonance imaging (MRI), performing systemati…

Prosthetic modelling and simulation

2020

Abstract Modelling of physical systems can be divided into two categories: physical and mathematical modelling. Physical modelling is a process in which we construct tangible scale models that look very much like the real system. In the past century, consider the animal models that have significantly influenced the development of disease treatment and artificial joints. However, scale models require a great deal of time and resources to develop and there are limits to what can be learned from them. Mathematical or behavioural modelling is a more abstract system used for studying a research question that does not necessarily lend itself to physical modelling. In these models, the system is s…

Scattering resonances and Pseudospectrum : stability and completeness aspects in optical and gravitational systems

2022

The general context of this thesis is an effort to establish a bridge between gravitational andoptical physics, specifically in the context of scattering problems using as a guideline concepts andtools taken from the theory of non-self-adjoint operators. Our focus is on Quasi-Normal Modes(QNMs), namely the natural resonant modes of open leaky structures under linear perturbationssubject to outgoing boundary conditions. They also are referred to as scattering resonances.In the conservative self-adjoint case the spectral theorem guarantees the completeness andspectral stability of the associated normal modes. In this sense, a natural question in the non-self-adjoint setting refers to the char…

static optimal estimation of joint accelerations for inverse dynamics problem solution

2002

In inverse dynamics computations, the accuracy of the solution strongly depends on the accuracy of the input data. In particular, estimated joint moments are highly sensitive to uncertainties in acceleration data. The aim of the present work was to improve classical inverse dynamics computations by providing an accurate estimation of accelerations. Accelerations are usually calculated from noise-polluted position data using numerical double differentiation, which amplifies measurement noise. The objective of the present paper is to use all available imperfect position and force measurements to extract optimum acceleration estimations. A weighted least-squares optimisation approach is used t…