Search results for "Juvenil"
showing 10 items of 450 documents
A controlled trial of intra-articular corticosteroids with or without methotrexate in oligoarticular juvenile idiopathic arthritis
2014
In contrast with the numerous controlled trials conducted in polyarticular or systemic juvenile idiopathic arthritis (JIA), little evidence-based information is available for oligoarticular JIA. As a result, the management of children with this subtype, which is the most prevalent in Western countries, is largely empiric. Intra-articular corticosteroid (IAC) injection is the therapy of first choice for oligoarthritis in many pediatric rheumatology centers. However, although IAC injections are usually highly efficacious, relapses of synovitis are common and sometimes occur only a few months after the procedure. It is still unclear whether concomitant administration of methotrexate (MTX) may …
Intra-articular corticosteroids versus intra-articular corticosteroids plus methotrexate in oligoarticular juvenile idiopathic arthritis: a multicent…
2017
Summary Background Little evidence-based information is available to guide the treatment of oligoarticular juvenile idiopathic arthritis. We aimed to investigate whether oral methotrexate increases the efficacy of intra-articular corticosteroid therapy. Methods We did this prospective, open-label, randomised trial at ten hospitals in Italy. Using a concealed computer-generated list, children younger than 18 years with oligoarticular-onset disease were randomly assigned (1:1) to intra-articular corticosteroids alone or in combination with oral methotrexate (15 mg/m 2 ; maximum 20 mg). Corticosteroids used were triamcinolone hexacetonide (shoulder, elbow, wrist, knee, and tibiotalar joints) o…
Early Treatment of Systemic Juvenile Idiopathic Arthritis with Canakinumab and Complete Remission After 2 Years of Treatment Suspension: Case Report …
2019
Systemic juvenile idiopathic arthritis (sJIA) is an autoinflammatory disease characterised by fever and arthritis. We describe the case of a 14-year-old girl hospitalised with fever associated with rash, myalgia, arthralgia and polyarticular involvement. Examinations revealed increased levels of C-reactive protein, erythrocyte sedimentation rate, ferritin, triglycerides, leukocytes, neutrophils, lactate dehydrogenase, fibrinogen, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT). Bone marrow biopsy showed polyclonal leukocyte activation. A genetic study revealed a heterozygous mutation of the MEFV gene, c.442G>C (E148Q), which is typical of…
Plasma markers of platelet and polymorphonuclear leukocyte activation in young adults with acute myocardial infarction
2005
Our goal was to evaluate some plasma markers of platelet and polymorphonuclear leukocyte (PMN) activation in a group of young adults with acute myocardial infarction (AMI) at the initial stage and after three months. We enrolled 49 AMI subjects aged<45 years and examined plasmatic levels of platelet factor 4 (PF4), β-thromboglobulin (β-TG), elastase and myeloperoxidase (MPO) using ELISA methods. PF4 and β-TG were increased, compared to control subjects, both at the initial stage and after 3 months. In control subjects and in AMI patients, at both times of observation, there was a significant and positive correlation between the two platelet parameters, while no correlation was present betwe…
Análisis de la narrativa infantil escrita por mujeres (1920-1939)
2012
Resumen basado en el de la publicación Título, resumen, palabras clave en español e ingles Se aborda el estudio de un corpus de cuentos infantiles publicados por mujeres en la prensa nacional de adultos entre 1920 y 1939. Son sus objetivos : hacer visible esa producción ; analizar las diferentes propuestas estéticas e ideológicas formalizadas en esta escritura y reinsertar esta producción artística en el sistema literario en el que se produjo, ya que nace dentro de éste y son las circunstancias históricas posteriores las que lo aíslan y lo convierten en una escritura menor. La visibilización de la escritura femenina infantil para niños se constituye en tres fases : autoras que publican en e…
Respiration and growth rates of F0 and F1 larval and juvenile European seabass Dicentrarchus labrax in response to ocean acidification and warming
2022
Ongoing climate change is leading to warmer and more acidic oceans. The future distribution of fish within the oceans depends on their capacity to adapt to these new environments. Only few studies have examined the effects of ocean acidification (OA) and warming (OW) on the metabolism of long-lived fish over successive generations. We therefore aimed to investigate the effect of OA on larval and juvenile growth and metabolism on two successive generations of European sea bass (Dicentrarchus labrax L.) as well as the effect of OAW on larval and juvenile growth and metabolism of the second generation. European sea bass is a large economically important fish species with a long generation time…
Photoperiodic regulation of life-history traits before and after eclosion: egg-to-adult development time, juvenile body weight and reproductive diapa…
2012
Photoperiod is the main environmental cue used by northern insects to predict the forthcoming seasonal changes and to adjust their life-history traits to fit these changes. We studied the effects of photoperiod on egg-to-adult development time, juvenile body mass and female reproductive diapause in two northern Drosophila montana populations with different patterns of voltinism. The most interesting findings were consistent between the populations: (1) when maintained before eclosion in short day conditions, representing early autumn, the flies developed faster and were lighter than when maintained in long day conditions, representing early summer, (2) photoperiodic time measurement is appa…
La gestión de expedientes juveniles de reforma (I): un análisis de su tramitación en la fiscalía provincial de valencia (2011)
2023
Se analizan la tramitación procesal de los expedientes penales incoados a menores de edad en la provincia de Valencia durante el año 2011, estudiando la exploración del menor y la derivación –o no– a mediación. Se deja para una segunda parte el análisis de los supuestos en que se realiza escrito de alegaciones, se sustancia vista y en su caso se impone medida. The procedural processing of criminal files initiated against minors in the province of Valencia during the year 2011 is analyzed, studying the exploration of the minor and the referral –or not– to mediation. The analysis of the cases in which a statement of allegations is made, the hearing is substantiated and, where appropriate, a m…
La delincuencia juvenil en España: cifras y datos de la estadística oficial (2002-2016)
2022
Se analizan las cifras que proporcionan las estadísticas oficiales españolas sobre delincuencia juvenil (anuarios del Ministerio del Interior, memorias de Fiscalía, estadísticas del Consejo General del Poder Judicial y explotación del Registro de Sentencias de Responsabilidad Penal de los Menores) en el periodo 2002-2016. Analysis of data provided by Spanish official statistics on juvenile delinquency (Home Office annual reports, reports of the Office of the Prosecutor, statistics of the General Council of the Judiciary and exploitation of the Record of Sentences of Criminal Responsibility of Minors) in the period 2002-2016.
“La responsabilidad penal del menor en España: mapa de una realidad geográficamente diversa a partir de la estadística oficial”
2022
Las estadísticas oficiales españolas evidencian que la aplicación de la Ley Orgánica Reguladora de la Responsabilidad Penal de los Menores encuentra aterrizajes muy diversos en las distintas regiones; se analizan y contrastan en esta contribución datos policiales, memorias de la Fiscalía, estadísticas del Consejo General del Poder Judicial y explotación del Registro de Sentencias de Responsabilidad Penal de los Menores, contrastándolos con datos poblacionales de los diferentes territorios, para evidenciar este extremo. PID2021- 123441NB-I00 The official Spanish data show that the application of the Organic Law Regulating the Criminal Responsibility of Minors involves very different practice…