Search results for "KER"
showing 10 items of 7682 documents
Serum Vitamin D as a Biomarker in Autoimmune, Psychiatric and Neurodegenerative Diseases.
2022
Vitamin D is a steroid hormone regulating calcium-phosphorus homeostasis, immune response and brain function. In the past thirty years, an increasing number of cohort studies, meta-analyses and randomized controlled trials (RTCs) evaluated the serum levels of 25-hydroxyvitamin D [25(OH)D], which is considered the Vitamin D status biomarker, in patients affected by neurological, psychiatric and autoimmune diseases. Although an association between low 25(OH)D serum levels and the prevalence of these diseases has been found, it is still unclear whether the serum 25(OH)D measurement can be clinically useful as a biomarker for diagnosis, prognosis and predicting treatment response in neurodegene…
Behind the scenes of artificial intelligence: a study of micro-work platforms in France
2019
Este artículo es una versión resumida del informe “Le Micro-travail en France. Derrière l’automatisation de nouvelles précarités au travail?» This article is a summarized version of the report "Le Micro-travail en France. Derrière l’automatisation de nouvelles précarités au travail?" .; International audience; Micro-work internet services allocate small, standardized tasks of data generation and annotation to crowds of providers. The outputs are mainly used to produce artificial intelligence solutions. It is an exemplary instance of the “platformization” of the economy, and of the transformations of labour that digital technologies bring about. To uncover the conditions under which micro-wo…
Optical quality of hyperopic and myopic phakic intraocular lenses
2013
Aims: To assess and compare the optical quality of the myopic and hyperopic implantable collamer lens (ICL) from its wavefront aberrations for different powers and pupil diameters. Settings and Design: Prospective study. Material and Methods: The wavefront aberrations of two myopic (−3 and −6 diopters (D)) and two hyperopic V4b ICLs (+3 and +6D) were measured in vitro . To assess and compare the optical quality of different powers of ICLs, we analyzed the root mean square (RMS) of total higher order aberrations (HOAs), trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration at 3- and 4.5-mm pupil. In addition, the point spread functions (PSFs) of each ICL evaluated were ca…
Assosiaatioiden ilotulituksesta koherentiksi kertomukseksi : kaksisuuntainen mielialahäiriö ja omaelämäkerrallisen kirjoittamisen terapeuttiset mahdo…
2016
Tässä tutkimuksessa tutkin omaelämäkerrallisen kirjoittamisen terapeuttisia mahdollisuuksia osana kaksisuuntaisesta mielialahäiriöstä kuntoutumista. Tutkimukseni pohjaa terapeuttisesta kirjoittamisesta ja omaelämäkerrallisesta kirjoittamisesta tuotetun tutkimustiedon soveltamiseen suhteessa Marya Hornbacherin, Terry Cheneyn ja Cecilia Aspin omaelämäkerrallisten romaanien kerrontaan ja sisältöön sekä henkilökohtaiseen kokemustietooni kaksisuuntaisesta mielialahäiriöstä kirjoittamisesta ja sen terapeuttisuudesta. Tutkimukseni aikana löytämäni teoriatieto vahvistaa tutkimistani omaelämäkerrallisista romaaneista ja omasta tekstistäni havaitsemieni terapeuttisuuden osatekijöiden paikkansapitävyy…
The matrix metalloproteinase and insulin-like growth factor system in oral cancer : a prospective clinical study
2017
Aim The absence of reliable single serum biomarkers for oral premalignant lesion (OPL) and oral squamous cell carcinoma (OSCC) limits early diagnosis, monitoring of advanced disease, and prediction of prognosis. Methods In this prospective study, serum levels of matrix metalloproteinase (MMP)-2, MMP-3, MMP-13, insulin-like growth factor (IGF)-1, and IGF-binding protein (IGFBP)-3 were measured in 81 untreated OSCC patients, 49 healthy subjects, and 75 individuals with OPLs, and correlated with clinicopathological parameters. Results Serum levels of MMP-3 were significantly higher in OSCC patients compared to healthy subjects (p=0.004). Mean IGF-1 and IGFBP-3 levels in OSCC patients were sign…
Inflammatory response elements, glycan, and proteome profiles as salivary biomarkers for the early diagnosis of OSCC
2021
El cáncer oral, sobre todo el, carcinoma oral de células escamosas (COCE), es la neoplasia maligna más común en la cavidad oral que se caracteriza por un mal pronóstico y una baja tasa de supervivencia, cuando se diagnostica en estadios avanzados. Puede ser tratado de forma efectiva si se detecta en estadios iniciales, mejorando el pronóstico. Por tanto, tras la prevención, el diagnóstico precoz se ha convertido en el principal objetivo en el manejo del cáncer oral, dado su impacto positivo en la supervivencia y calidad de vida de estos pacientes. A menudo, los escasos síntomas iniciales pasan desapercibidos y la enfermedad se descubre en fases avanzadas, por lo que se requiere mejorar el d…
The matrix metalloproteinase and insulin-like growth factor system in oral cancer – a prospective clinical study
2017
Eik Schiegnitz,1 Peer W Kämmerer,2 Holger Schön,1 Christoph Gülle,1 Manfred Berres,3,4 Keyvan Sagheb,1 Bilal Al-Nawas5 1Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center, Johannes Gutenberg University of Mainz, Mainz, 2Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Centre Rostock, Rostock, 3Department of Mathematics and Technology, University of Applied Sciences Koblenz, Remagen, 4Institute of Medical Biometry, Epidemiology and Informatics, Johannes Gutenberg University of Mainz, Mainz, 5Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Centre, Martin-Luther University Ha…
The Essential Oil of
2019
Many chemicals used nowadays for the preservation of cultural heritage pose a risk to both human health and the environment. Thus, it is desirable to find new and eco-friendly biocides that can replace the synthetic ones. In this regard, plant essential oils represent effective alternatives to synthetic substances for the preservation of historical monuments. Thymbra capitata (syn. Thymus capitatus) is a medicinal and aromatic plant growing in the Mediterranean area and endowed with important pharmacological properties related to its essential oil. Among them, the antimicrobial ones make the T. capitata essential oil an ideal candidate for industrial applications; for instance, as biocide f…
Tekstin ymmärtämisen arviointi peruskoulun kolmannella luokalla
2001
Effects of training background to acute psychological stress biomarkers
2016
Stressi on laajalti tutkittu aihe ja kroonisen stressin aiheuttamat terveysvaikutukset ovat merkittäviä maailmassa. Stressi käsitteenä voidaan ajatella tarkoittavan tilannetta, jolloin homeostaasia järkytetään. Stressi voidaan jakaa henkiseen ja fyysiseen sekä pitkäaikaiseen ja lyhytkestoiseen. Ihmisen kokiessa stressiä, niin henkistä tai fyysistä, tapahtuu hermoston toiminnan johdosta erilaisia fysiologisia muutoksia ihmiskehossa. Reaktio stressiin johtaa esimerkiksi sykkeen kiihtymiseen, verenpaineen kohoamiseen sekä erilaisten hormonien erittymiseen, kuten: adrenaliini ja kortisoli. Tässä tutkimuksessa on tarkoituksena tutkia miten erilaisen harjoitustaustan omaavien henkilöiden fysiolog…