Search results for "KIR"

showing 10 items of 3870 documents

Toxicity of biomining effluents to Daphnia magna: Acute toxicity and transcriptomic biomarkers

2018

Increasing metal consumption is driving the introduction of new techniques such as biomining to exploit low grade ores. The biomining impacts notably aquatic ecosystems, yet, the applicability of ecotoxicological tests to study the complex mixture effects of mining waters is insufficiently understood. The aim of the present work was to test if transcriptomic biomarkers are suitable and sensitive for the ecotoxicity assessment of biomining affected waters. The study site had been affected by a multimetal biomine, and the studied water samples formed a concentration gradient of contamination downstream from the biomining site. Cadmium and nickel were used as positive controls in the toxicity …

0301 basic medicinelähetti-RNAHealth Toxicology and Mutagenesis010501 environmental sciences01 natural sciencesNickelmetallitmixture toxicityCadmiumbioliuotusbiologyvesien saastuminenChemistryGeneral MedicineContaminationPollutiontranskriptio (biologia)Environmental chemistryToxicitykaivosvesiCadmiumkaivoksetmining effluentEnvironmental EngineeringmRNAta1172Daphnia magnametalschemistry.chemical_elementBiominingmyrkyllisyysMining03 medical and health sciencesToxicity Tests AcuteAnimalsEnvironmental ChemistryEffluent0105 earth and related environmental sciencesPublic Health Environmental and Occupational HealthGeneral Chemistrybiology.organism_classificationAcute toxicitysub-lethal030104 developmental biologyDaphniaGene Expression RegulationmarkkeritvesikirputbioleachingEcotoxicityTranscriptomeBiomarkersChemosphere
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The role of immunogenetics in covid‐19

2021

Coronavirus disease 2019 (COVID-19) is induced by SARS-CoV-2 and may arise as a variety of clinical manifestations, ranging from an asymptomatic condition to a life-threatening disease associated with cytokine storm, multiorgan and respiratory failure. The molecular mechanism behind such variability is still under investigation. Several pieces of experimental evidence suggest that genetic variants influencing the onset, maintenance and resolution of the immune response may be fundamental in predicting the evolution of the disease. The identification of genetic variants behind immune system reactivity and function in COVID-19 may help in the elaboration of personalized therapeutic strategies…

0301 basic medicinemedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)ReviewDiseaseImmunogeneticsHuman leukocyte antigenSeverity of Illness IndexCatalysisSARS‐CoV‐2ABO Blood-Group SystemInorganic Chemistrylcsh:Chemistry03 medical and health sciences0302 clinical medicineCOVID‐19HLA AntigensmedicineImmunogeneticsHumansGenetic Predisposition to DiseaseGenetic variabilityPhysical and Theoretical ChemistryIntensive care medicineMolecular Biologylcsh:QH301-705.5SpectroscopyAB0business.industrySARS-CoV-2Organic ChemistryImmunityCOVID-19General MedicineImmunosenescencemedicine.disease3. Good healthComputer Science ApplicationsKIRHLA030104 developmental biologylcsh:Biology (General)lcsh:QD1-999030220 oncology & carcinogenesisIdentification (biology)Disease SusceptibilityCytokine stormbusiness
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Prokaryotic assemblages within permafrost active layer at Edmonson Point (Northern Victoria Land, Antarctica)

2018

This study was aimed at gaining insights on the prokaryotic community (in terms of both taxonomic composition and activities) inhabiting the active layer at Edmonson Point, an ice-free area on the eastern slope at the foot of Mount Melbourne (Northern Victoria Land, Antarctica). Samples were collected during the thawing period, when microbial physiological activities are restored to utilize previously frozen organic substrates. Despite the very small cell sizes (600 daltons) substrates, as indicated also by the obtained rates of enzymatic hydrolytic activities over proteolytic, glycolitic and phosphoric compounds. Taxonomical composition showed that Proteobacteria, Actinobacteria and Firmic…

0301 basic medicinemetabolic activitiesFirmicutesta1172seasonally thawed active layerSoil ScienceikiroutaAntarctica; Metabolic activities; Prokaryotic community; Seasonally thawed active layer; Microbiology; Soil SciencePermafrostMicrobiologyActinobacteria03 medical and health sciencesAbundance (ecology)Organic mattermikrobitaineenvaihduntaNitrogen cycleAntarctica Metabolic activities Prokaryotic community Seasonally thawed active layer Microbiology Soil Sciencechemistry.chemical_classificationbiologyEcologyta1183prokaryotic communitybiology.organism_classificationmikrobisto030104 developmental biologychemistryHabitatEnvironmental scienceAntarcticaantarktinen alueProteobacteria
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Book Review: James Midgley, Espen Dahl and Amy Conley Wright (eds) Social Investment and Social Welfare: International and Critical Perspectives

2018

05 social sciencesSocial Welfareta5142social investmentInvestment (macroeconomics)0506 political scienceWrightkirja-arvostelut0502 economics and businessPolitical Science and International Relations050602 political science & public administrationEconomic historySociology050207 economicsbook reviewsocial welfareCritical Social Policy
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The integration of content and language in students’ task answer production in the bilingual classroom

2016

The notion of content and language integration has recently become a key topic of inquiry in research on content and language integrated learning and other kinds of bilingual educational programmes. Understanding what integration is and how it happens is of fundamental importance not only for researchers interested in gauging the possibilities and limitations of bilingual programmes, but also for practitioners seeking optimal ways to support student development. This study investigates integration as it takes place in the context of collaborative writing in the classroom. Drawing on conversation analytic methodology, text production is investigated as a social and sequentially evolving phen…

050101 languages & linguisticsLinguistics and LanguageCollaborative writingcontent and language integrationconversation analysisTeaching methodDiscourse analysista6121Language and LinguisticsEducationTask (project management)Language integrationPedagogyProduction (economics)0501 psychology and cognitive sciencesta516yhteisöllinen oppiminenContent (Freudian dream analysis)CLILkeskustelunanalyysi05 social sciences050301 educationpeer interactionwritingContent and language integrated learningvieraskielinen opetusPsychology0503 educationkirjoittaminen
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On the participatory agency of texts: Using institutional forms in performance appraisal interviews

2020

Abstract Drawing on studies of the performative effects and agency of texts in organizations, the paper investigates how the agency of texts figures through their participatory status in interaction. The empirical data for the study consist of video-recorded performance appraisal interviews in a Finnish public organization in which the interaction relies heavily on an appraisal form. The data are analyzed through a sequential analysis that draws on multimodal conversation analysis and ethnographic knowledge. The analysis shows that the human participants orient to three different acts that are inscribed in the textual document: 1) presenting demands for the participants; 2) offering topics …

050101 languages & linguisticsLinguistics and LanguagePerformance appraisalvuorovaikutusDiscourse analysismedia_common.quotation_subjectinteractionorganizational textslomakkeetLanguage and Linguistics0502 economics and businessPedagogyAgency (sociology)0501 psychology and cognitive sciencesConversationSociologyperformance appraisal interviewsmedia_commonasiakirjatkeskustelunanalyysiCommunication05 social sciencesApplied linguisticsCitizen journalismtoimijuusPragmaticstekstintutkimusPhilosophytextual agencyarviointikeskusteluconversation050203 business & managementText & Talk
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If you can defend your own point of view, you're good : Norms of voice construction in student writing on an international Master's programme

2019

Abstract This ethnographically oriented study followed the writing experiences of four students on an international masters programme in Finland. Gathering a range of data, the study set out to examine what counts as good writing on a programme with a very diverse student body in which English is used as a lingua franca. Both teachers and students emphasised the importance of arguing one's ‘own point of view’ in academic writing, and teachers often formed impressions of students on the basis of their texts, drawing attention particularly to their use of metadiscourse markers (e.g., self-mentions, attitude markers and hedges). The present article therefore combines a quantitative analysis of…

050101 languages & linguisticsLinguistics and LanguagemaisteriohjelmatmetadiscourseMetadiscourseta6121Lingua francaMaster's programmesLanguage and LinguisticsEducationmetadiskurssiPedagogyAcademic writing0501 psychology and cognitive sciencesStudent writingSet (psychology)computer.programming_languagePoint (typography)opiskelijatstudents05 social sciencesacademic writing050301 educationnäkökulmawritingpoint of viewMaster sPsychology0503 educationDisciplinecomputerkirjoittaminenvoice constructionEnglish for Specific Purposes
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Effectiveness of child protection practice models : a systematic review

2020

Background Attempts to improve child protection outcomes by implementing social work practice models embedded in a particular theory and practice approach, have increased internationally over the past decade. Objective To assess the evidence of the effectiveness of child protection practice models in improving outcomes for children and families. Participants and setting Children < 18 years and their families involved in child protection services. Methods A systematic review was conducted to synthesize evidence regarding the effectiveness of child protection practice models. Systematic searches across 10 electronic databases and grey literature were conducted to identify quasi-experimental s…

050103 clinical psychologymedia_common.quotation_subjectPoison controlchild protectiontoimintamallitOccupational safety and healthsystematic reviewInjury preventionDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesFamily10. No inequalityChildsystemaattiset kirjallisuuskatsauksetmedia_commonSelection biasMedical educationSocial worksocial workChild Protective Services05 social sciencesHuman factors and ergonomicsSocial SupportGrey literaturekäytäntöpractice modelssosiaalityöPsychiatry and Mental healthlastensuojeluChild protectionPediatrics Perinatology and Child HealthPsychology050104 developmental & child psychology
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Ajatuksella ja ahkeruudella kolmen suvun vaiheista neljältä vuosisadalta

2018

Kirja-arvio teoksesta Immonen, Perttu: Suomen rahvaan historia. Kolmen suvun elämää keskiajalta 1800-luvulle. Atena Kustannus Oy, 2017. 639 sivua. ISBN 978- 952-300-335-4. Perttu Immonen yhdistää teoksessaan mielenkiintoisesti ja elävästi mikro- ja makrohistorian varhaismodernin ajan Suomessa. Hän seuraa kronologisesti kolmen eri seutukunnan: LänsiSuomen Sastamalan, Itä-Suomen Rantasalmen ja Pohjanmaan Kokkolan tapahtumia. Poikkeuksellisen ankarien aikojen kuvauksesta muodostuu moniulotteinen ja alueiden erilaisia kohtaloita tarkasteleva analyysi. nonPeerReviewed

17th centurymakrohistoria18th century19th centurykäsityöläisethistoriaSastamalasääty-yhteiskuntaporvaristokeskiaikaKokkolatilallisetkirja-arvostelutpapistomikrohistoriasotilaatRantasalmi1600-lukukonteksti1800-luku1700-lukutalonpojatsäädyt
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Vallan verkostoissa : Per Brahe ja hänen klienttinsä 1600-luvun Ruotsin valtakunnassa

2011

17th centurysocial networksklienttijärjestelmäkirjeetnobilitystate buildingpatronageletter rhetoricRuotsin vallan aikapatronus-klientti -suhteetBrahe Pietarisosiaaliset suhteetpatron-client relationshipskirjeretoriikkasosiaaliset verkostotvaltionrakennushallintohistoriaaatelivaltarakenteet1600-luku
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