Search results for "KNOWLEDGE"
showing 10 items of 3108 documents
A Randomised Controlled Trial to Test the Effectiveness of Planning Strategies to Improve Medication Adherence in Patients with Cardiovascular Disease
2017
Background Low levels of adherence to medication prescribed to treat and manage chronic disease may lead to maladaptive health outcomes. Theory-based, easy-to-administer interventions that promote patients’ effective self-regulation of their medication-taking behaviour are needed if adherence is to be maximised. We tested the effectiveness of an intervention adopting planning techniques to promote medication adherence. Methods Outpatients with cardiovascular disease (N = 71) were allocated to either an experimental condition, in which participants were asked to form implementation intentions and coping plans related to their treatment, or to a no-planning control condition, in which partici…
Developing teachers' professional expertise through collaboration in an innovative ICT‐based learning environment
2004
Recent research emphasizes the context‐specific nature of professional knowledge and expertise, implying that developing novel practices in authentic environments is a prerequisite for teachers' professional development. The aim of this study was to find out how teachers develop their practical knowledge and expertise through shared planning and to evaluate an innovative learning project carried out in an ICT‐based environment. Two secondary school teachers of history participated in this study. The data were gathered using a multi‐methodological approach (video recordings, interviews and questionnaires). The results are described in terms of the teachers' shared experiences and their incre…
Cellular Models and Assays to Study NLRP3 Inflammasome Biology
2020
The NLRP3 inflammasome is a multi-protein complex that initiates innate immunity responses when exposed to a wide range of stimuli, including pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs). Inflammasome activation leads to the release of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18 and to pyroptotic cell death. Over-activation of NLRP3 inflammasome has been associated with several chronic inflammatory diseases. A deep knowledge of NLRP3 inflammasome biology is required to better exploit its potential as therapeutic target and for the development of new selective drugs. To this purpose, in the past few years, several tools have…
Catalyzing transcriptomics research in cardiovascular disease: The CardioRNA COST action CA17129
2019
WOS: 000474931400001
Guanxi, trust and reward-based crowdfunding success: a Chinese case
2019
Purpose This paper aims to examine different hypotheses concerning the effects of guanxi on the reward-based crowdfunding project fundraising. Specifically, this study provides new insights into how guanxi and guanxi intensity may affect reward-based crowdfunding success and project performance in the Chinese context. Design/methodology/approach The research data including 989 crowdfunding projects were collected from zhongchou.com which is the largest reward-based crowdfunding platform in a one-year period (2014.1-2014.12). The hypotheses are tested by using robust OLS regressions and robust logistic regressions. Robustness check was also conducted to test the validation of the results. F…
Toward completion of the Earth’s proteome: an update a decade later
2017
Protein databases are steadily growing driven by the spread of new more efficient sequencing techniques. This growth is dominated by an increase in redundancy (homologous proteins with various degrees of sequence similarity) and by the incapability to process and curate sequence entries as fast as they are created. To understand these trends and aid bioinformatic resources that might be compromised by the increasing size of the protein sequence databases, we have created a less-redundant protein data set. In parallel, we analyzed the evolution of protein sequence databases in terms of size and redundancy. While the SwissProt database has decelerated its growth mostly because of a focus on i…
A Proposed Knowledge Based Approach for Solving Proteomics Issues
2010
In this paper we present a novel knowledge-based approach that aims at helping scientists to face and resolve a large number of proteomics problem. The system architecture is based on an ontology to model the knowledge base, a reasoner that starting from the user's request and a set of rules builds the workflow of tasks to be done, and an executor that runs the algorithms and software scheduled by the reasoner. The system can interact with the user showing him intermediate results and several options in order to refine the workflow and supporting him to choose among different forks. Thanks to the presence of the knowledge base and the modularity provided by the ontology, the system can be e…
Opinion of the Patients About an Internet-Based Psychological Treatment Protocol
2015
Emotional disorders (depression and anxiety disorders) are highly prevalent. Currently, there is evidence showing the efficacy of disorder-specific cognitive-behavior therapy for emotional disorders. However, high comorbidity rates among emotional disorders have led some researchers to shift the focus to treatment strategies that might be more widely effective across these diverse conditions (transdiagnostic approach). Another important line of research in the literature is Internet-based psychotherapy. An increasing number of meta-analyses have shown the efficacy and effectiveness of Internet-based cognitive-behavior treatment protocols for emotional disorders. Nevetherless, little is know…
Teaching mechanical oscillations using an integrate curriculum
1997
Abstract A set of teaching materials dealing with harmonic oscillations was developed as part of a research project investigating the influence of different pedagogical tools on physics learning. The materials incorporate simulation software and laboratory activities associated with Teacher and Student Units. The project involved research groups at seven Italian universities and the materials have been trialled in high schools nation‐wide. This paper describes the experimental protocol for the use of these materials in pilot classes and the evaluation of student learning and teacher training results. The intervention was found to improve physics education at school praxis level and to promo…
INTERVENCIÓN PSICOSOCIAL EN ESPACIOS DE ALTA DIVERSIDAD EXPERIENCIA INTERCULTURAL Y BUENA PRAXIS
2021
espanolPsychosocial interventional approaches in reducing intergroup biases can be divided into two areas: intragroup and intergroup. The former includes work with counterstereotypespecimens (Plant et al., 2009), strategies based on cognitive dissonance (Festinger, 1957, cited in Rodriguez, 2019) and the promotion of empathy (Galinsky & Moskowitz, 2000; Stephan & Finlay, 1999). Intergroup strategies are those based on the contact hypothesis (Allport, 1954, cited in Rodriguez, 2019) and those based on the theory of social categorization or sociocognitive strategies (Tajfel & Turner, 1979). The research was ascribed to the interventional research model proposed by Rothman and Thomas (1994), c…