Search results for "KRS_SD"

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Molecular response to TBT stress in marine sponge Suberites domuncula: proteolytical cleavage and phosphorylation of KRS_SD protein kinase

2003

Abstract Marine sponges as sessile filter feeders are inevitably under a constant influence of changes in their environment. Mediation of extracellular signals and regulation of cellular response to environmental stress is a key function of cellular protein kinases. Expression, proteolytical cleavage and phosphorylation of stress-responsive KRS_SD protein kinase, in control and tributyl-tin (TBT) treated sponges were investigated. In control sponge, two KRS_SD proteins were expressed: KRS_SD1 (54 kDa) corresponding to KRS_SD calculated molecular weight, and KRS_SD2 (50 kDa). Exposure of sponges to TBT resulted in alteration of KRS_SD1 and KRS_SD2 expression levels and their phosphorylation …

chemistry.chemical_classificationbiologymedicine.diagnostic_testKinaseProteolysisKRS_SD; marine sponge; protein kinase; stress; Tributyl-tinAquatic Sciencebiology.organism_classificationCleavage (embryo)Molecular biologySuberites domunculaEnzymeBiochemistrychemistrymedicineExtracellularPhosphorylationProtein kinase AEcology Evolution Behavior and SystematicsJournal of Experimental Marine Biology and Ecology
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