Search results for "Kaempferols"

showing 5 items of 5 documents

Isolation and identification of new anthraquinones from Rhamnus alaternus L and evaluation of their free radical scavenging activity

2018

From the butanolic and the ethyl acetate extracts of Rhamnus alaternus L root bark and leaves, three new anthraquinone glycosides, alaternosides A-C (1,4,6,8 tetrahydroxy-3 methyl anthraquinone 1-O-ß-D-glucopyranosyl-4,6-di-O-α-L-rhamnopyranoside (1); 1,2,6,8 tetrahydroxy-3 methyl anthraquinone 8-O-ß-D-glucopyranoside (2) and 1, 6 dihydroxy-3 methyl 6 [2′-Me (heptoxy)] anthraquinone (3)) were isolated and elucidated together with the two known anthraquinone glycosides, Physcion-8-O-rutinoside (4) and emodin-6-O-α-L-rhamnoside (5) as well as with the known kaempferol-7-methylether (6), β-sitosterol (7) and β-sitosterol-3-O-glycoside (8). Their chemical structures were elucidated using spectr…

DPPHRadicalEthyl acetateAnthraquinonesPlant Science01 natural sciencesBiochemistryAnthraquinoneMedicinal chemistryAnalytical Chemistrychemistry.chemical_compoundRhamnus alaternusAnthraquinonesGlycosidesKaempferolschemistry.chemical_classificationbiologyMolecular Structure010405 organic chemistryPlant ExtractsOrganic ChemistryGlycosideFree Radical Scavengersbiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistryRhamnuschemistryvisual_artvisual_art.visual_art_mediumBark
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Two New Glycosides from Astragalus caprinus

2001

A new glycoside of flavonol (1) and a new glycoside of a cycloartane-type triterpene (2) were isolated from the leaves and the roots of Astragalus caprinus, respectively. Their structures were elucidated in turn by spectroscopic data interpretation as 3-O-[[beta-D-xylopyranosyl(1-->3)-alpha-L-rhamnopyranosyl(1-->6)][beta-D-apiofuranosyl(1-->2)]]-beta-D-galactopyranosyl kaempferol (1) and 3-O-(beta-D-xylopyranosyl)-24-O-(beta-D-glucopyranosyl)-20,25-epoxycycloartane-3beta,6alpha,16beta,24alpha-tetrol (2).

Magnetic Resonance SpectroscopyTunisiaSpectrophotometry InfraredStereochemistryFlavonoidSaponinPharmaceutical ScienceSpectrometry Mass Fast Atom BombardmentPharmacognosyPlant RootsAnalytical Chemistrychemistry.chemical_compoundTriterpeneDrug DiscoveryTetrasaccharideGlycosidesKaempferolsFlavonoidsPharmacologychemistry.chemical_classificationPlants MedicinalHydrolysisOrganic ChemistryGlycosideSaponinsTriterpenesTerpenoidPlant LeavesComplementary and alternative medicinechemistryMolecular MedicineSpectrophotometry UltravioletKaempferolJournal of Natural Products
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Nutraceutical Value of Pantelleria Capers (Capparis spinosa L.)

2019

Abstract: Unopened flower buds of Capparis spinosa L. (capers), generally used in the Mediterranean area as food flavoring, are known to be a good source of bioactive compounds. The aim of this work was to evaluate the nutraceutical value of salt-fermented capers collected from different areas of Pantelleria Island (Italy), testing their methylglyoxal and glyoxal trapping capacity and antioxidant activity by 2,2-diphenyl-1-picryl hydrazyl (DPPH), [2,2-azinobis(3-ethylben- zothiazoline-6-sulfonic acid)] diammonium salt (ABTS), and oxygen radical absorbance capacity (ORAC) assays. Hydrophilic extracts were also characterized by high-performance liquid chromatography–electrospray ionization/ma…

Oxygen radical absorbance capacity030309 nutrition & dieteticsDPPHFlavonoidGlucosinolatesAntioxidantsCapparis spinosa03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyfoodFlavonolsPhenolsnutraceutical propertiesFood scienceKaempferolsChromatography High Pressure LiquidPantelleria Island caperschemistry.chemical_classificationFlavonoids0303 health sciencesABTSPlant ExtractsCapparis spinosa04 agricultural and veterinary sciencesnutraceutical propertie040401 food sciencefood.foodSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeCapparischemistryItalymethylglyoxal and glyoxal trapping capacityhydrophilic extract compositionDietary SupplementsSeedsQuercetinQuercetinKaempferolFood Science
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Kaempferol as a dietary anti-inflammatory agent: current therapeutic standing

2020

Inflammation is a physiological response to different pathological, cellular or vascular damages due to physical, chemical or mechanical trauma. It is characterized by pain, redness, heat and swelling. Current natural drugs are carefully chosen as a novel therapeutic strategy for the management of inflammatory diseases. Different phytochemical constituents are present in natural products. These phytochemicals have high efficacy both in vivo and in vitro. Among them, flavonoids occur in many foods, vegetables and herbal medicines and are considered as the most active constituent, having the ability to attenuate inflammation. Kaempferol is a polyphenol that is richly found in fruits, vegetabl…

medicine.drug_classPhytochemicalsAnti-Inflammatory AgentsPharmaceutical ScienceBiological AvailabilityReviewChemical FractionationAnti-inflammatoryAnalytical Chemistrylcsh:QD241-441therapeutic utility03 medical and health scienceschemistry.chemical_compoundStructure-Activity Relationship0302 clinical medicinelcsh:Organic chemistryDrug DiscoveryToxicity TestsmedicineAnimalsHumansPhysical and Theoretical ChemistryKaempferols030304 developmental biologyTherapeutic strategyFlavonoids0303 health sciencesBiological ProductskaempferolPlants MedicinalTraditional medicineOrganic Chemistryfood and beveragesKaempferol Anti-Inflammatory TherapyBioavailabilityReview articlechemistryPhytochemicalChemistry (miscellaneous)Polyphenolinflammation030220 oncology & carcinogenesisDietary SupplementsMolecular MedicineKaempferol
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Steroid activities comparison of natural and food wrap compounds in human breast cancer cell lines

2004

Abstract In this study, we tested and compared the endocrine disruption activities of compounds in materials used to package foods (bisphenol A, bisphenol F, and bisphenol A diglycidylether BADGE) with natural molecules (genistein, apigenin, kaempferol, and tangeretin) in the human breast cancer cell lines MCF-7 (ER + ) and MDA-MB453 (AR + ; GR + ). Octylphenol was also chosen as a xenoestrogen reference. Two compounds had no estrogenic activity: BADGE and tangeretin. Genistein was the most active compound in the E-Screen assay with MCF-7, followed by octylphenol, bisphenol F, bisphenol A and apigenin, with kaempferol the least potent. All estrogenic compounds competed with 17β-estradiol fo…

medicine.medical_specialtyBisphenol A[SDV]Life Sciences [q-bio]medicine.medical_treatmentGenisteinAntineoplastic AgentsBreast NeoplasmsEndocrine SystemToxicologySteroid03 medical and health scienceschemistry.chemical_compoundTangeretin0302 clinical medicinePhenolsInternal medicineTumor Cells CulturedmedicineAnticarcinogenic AgentsHumansEstrogens Non-SteroidalApigeninBenzhydryl CompoundsKaempferolsComputingMilieux_MISCELLANEOUS030304 developmental biologyFlavonoids0303 health sciencesDose-Response Relationship DrugFood PackagingGeneral MedicineFlavonesGenistein3. Good health[SDV] Life Sciences [q-bio]XenoestrogenEndocrinologyReceptors EstrogenchemistryMCF-7Receptors Androgen030220 oncology & carcinogenesisApigeninCarcinogensEpoxy CompoundsFemaleKaempferolhormones hormone substitutes and hormone antagonistsFood Science
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