Search results for "Karnofsky Performance Status"

showing 5 items of 25 documents

Orphan symptoms in advanced cancer patients followed at home

2013

Abstract Orphan symptoms are rarely assessed, particularly at home. The aim of this multicenter prospective study was to assess the prevalence of these symptoms and eventual factors possibly associated in advanced cancer patients at admission of a home care program. A prospective study was performed at three home care programs in Italy. Patients' data were collected, including age, sex, diagnosis, and Karnofsky status. Possible contributing factors were analyzed; preexisting neurological diseases, cerebral metastases, hyperthermia, diabetes, a state of dehydration clinically evident and/or oliguria, possible biochemical parameters when available, data regarding recent chemotherapy, opioids …

MyoclonusMalemedicine.medical_specialtyPalliative careHiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; Tenesmus; Aged; Analgesics Opioid; Female; Fentanyl; Hiccup; Home Care Services; Hospitalization; Humans; Italy; Karnofsky Performance Status; Male; Myoclonus; Neoplasms; Prospective Studies; Pruritus; Sweating; Oncology; Medicine (all)Hiccup; Home care; Myoclonus; Palliative care; Pruritus; Sweating; TenesmusSweatingOpioidSettore MED/42 - Igiene Generale E ApplicataHome careFentanylHiccupPrurituOliguriaInternal medicineDiabetes mellitusNeoplasmsMedicineHumansVesical tenesmusProspective StudiesKarnofsky Performance StatusProspective cohort studyAgedAnalgesicsbusiness.industryPruritusMedicine (all)Tenesmusmedicine.diseaseHome Care ServicesAnalgesics OpioidFentanylHospitalizationDistressItalyOncologyAnesthesiaPalliative careFemalemedicine.symptombusinessMyoclonusMyoclonumedicine.drug
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NCOG-10. FACTORS INFLUENCING NEUROCOGNITIVE FUNCTION IN PATIENTS WITH NEUROEPITHELIAL TUMORS

2017

Though cognitive function is proven to be an independent predictor of survival in patients with intrinsic brain tumors, higher cognitive functions are still seldom studied. Aim of this study was to assess neurocognitive function and to identify risk factors for neurocognitive deficits in patients with intrinsic brain tumors. 103 patients with primary neuroepithelial tumors who received tumor resections or biopsies were included in this prospective study. The following data was acquired: mini-mental state examination, preoperative tumor volume, WHO grade, tumor entity and location, and the Karnofsky performance status scale. Furthermore, patients conducted an extensive neuropsychological tes…

OncologyCancer Researchmedicine.medical_specialtyKarnofsky Performance Statusbusiness.industryNeuroepithelial tumorsRisk identificationAbstractsOncologyInternal medicinemedicineIn patientNeurology (clinical)businessCognitive impairmentNeurocognitiveNeuro-Oncology
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Centre characteristics and procedure-related factors have an impact on outcomes of allogeneic transplantation for patients with CLL: a retrospective …

2017

Abstract Introduction:Even in the era of novel targeted therapies for the treatment of Chronic Lymphocytic Leukemia (CLL) patients, such as BTK, PI3K and BCL2 inhibitors, allogeneic hematopoietic stem cell transplantations (alloHCT) will remain an important treatment option for a subset of patients with very high risk CLL. The current study focused on the impact of center and procedure-related factors on outcomes after alloHCT, taking into account the impact of patient- and disease-related risk factors. Patients and Methods:Data of 684 CLL patients who received a first alloHCT between 2000 and 2011 were analyzed. Their data were collected as part of the EBMT CLL Data Quality Initiative. Out…

OncologyMaleTransplantation ConditioningCancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2]Chronic lymphocytic leukemiaMedizinQUALITY MANAGEMENT-SYSTEMKaplan-Meier Estimaterisk factor analysisGUIDELINESBiochemistryallogeneic stem cell transplantation; centre effects; chronic lymphocytic leukaemia; frailties; risk factor analysiscentre effectsTransplantation Conditioning / methods0302 clinical medicineRecurrenceRisk Factorsallogeneic stem cell transplantationLeukemia Lymphocytic Chronic B-Cell / mortalityRegistriesDelivery of Health Care / statistics & numerical dataIBRUTINIBddc:6160303 health sciencesALEMTUZUMABHazard ratioHematopoietic Stem Cell TransplantationProfessional PracticeHematologyMiddle Aged3. Good healthEurope030220 oncology & carcinogenesisABT-199CohortSURVIVALAlemtuzumabFemaleEurope / epidemiologymedicine.drugAdultmedicine.medical_specialtyAllogeneic transplantationImmunologyLower riskDIAGNOSISSettore MED/01 - Statistica Medica03 medical and health sciencesLeukemia Lymphocytic Chronic B-Cell / therapyHematopoietic Stem Cell Transplantation / methodsInternal medicinemedicineHumansKarnofsky Performance Status030304 developmental biologyAgedRetrospective Studiesbusiness.industryProportional hazards modelCHRONIC LYMPHOCYTIC-LEUKEMIARetrospective cohort studySTEM-CELL TRANSPLANTATIONCell Biologymedicine.diseaseLeukemia Lymphocytic Chronic B-CellConfidence intervalSurgeryProfessional Practice / statistics & numerical dataTransplantationbusinessDelivery of Health Carefrailtieschronic lymphocytic leukaemia030215 immunologyRESPONSES
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The Role of Religiosity in Symptom Expression of Advanced Cancer Patients

2021

Aim: The aim of this study was to assess the religious pattern and its impact on symptom expression in patients with advanced cancer. Methods: A consecutive sample of advanced cancer patients screened at admission to palliative care. Standard epidemiological data were recorded. Patients were asked about their religious beliefs, the degree of social relationship to existing religions, the role of religion in their life, and the frequency of their prayer. The Edmonton Symptom Assessment Scale (ESAS) and Hospital Anxiety Depression scale (HADS) were assessed. Results: Two-hundred-eighty-three patients were screened. Age and gender were found to be independently correlated with religious belief…

Oncologymedicine.medical_specialtyPalliative careCONSECUTIVE SAMPLEReligiosityreligiosity.NeoplasmsInternal medicinemedicineHumansadvanced cancerIn patientKarnofsky Performance StatusAgedpalliative carebusiness.industryGeneral MedicineanxietyAdvanced cancerreligiosityReligionExpression (architecture)AnxietyFemaleSymptom Assessmentmedicine.symptombusiness
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Compliance with patient-reported outcome assessment in glioma patients: predictors for drop out

2017

Abstract Background Patient-reported outcomes are of high importance in clinical neuro-oncology. However, assessment is still suboptimal. We aimed at exploring factors associated with the probability for a) drop out of study and b) death during follow-up. Methods Patients were assessed twice during follow-up visits scheduled within 3 to 5 months of each other by using 3 validated patient-reported outcome measures (t1: first assessment, t2: second assessment). As “death” was seen as a competing risk for drop out, univariate competing risk Cox regression models were applied to explore factors associated with dropping out (age, gender, WHO grade, living situation, recurrent surgery, Karnofsky …

medicine.medical_specialtyMotor dysfunctionKarnofsky Performance Statusbusiness.industryProportional hazards modelMedicine (miscellaneous)Original Articlesmedicine.diseasehumanities03 medical and health sciences0302 clinical medicinePhysical functioning030220 oncology & carcinogenesisDrop outInternal medicineGliomamedicinePhysical therapyDistress ThermometerPatient-reported outcomebusiness030217 neurology & neurosurgeryNeuro-Oncology Practice
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