Search results for "Kawasaki"

Studio neurofisiologico dei potenziali evocati uditivi e visivi in bambini affetti da malattia di Kawasaki: contributo personale.

2007

BRAINSTEM AUDITORY EVOKED POTENTIALS AND VISUAL POTENTIALS IN KAWASAKI DISEASE: EXPRESSION OF CNS VASCULITIS?

2015

Kawasaki disease (KD) is an acute, self-limited vasculitis of infants and children that is nowadays the most common cause of acquired heart disease in children. Transient sensorineural hearing loss (20 to 35 dB) is a possible complication of acute phase KD and may be related to salicylate toxicity in some patients.

Oral necrotizing microvasculitis in a patient affected by Kawasaki disease

2007

Kawasaki disease (KD) was first described in 1967 by Kawasaki, who defined it as ?mucocutaneous lymph node syndrome?. KD is an acute systemic vasculitis, which mainly involves medium calibre arteries; its origin is unknown, and it is observed in children under the age of 5, especially in their third year. The principal presentations of KD include fever, bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, changes in the extremities, rash, and cervical lymphadenopathy. Within KD, oral mucositis ? represented by diffuse mucous membrane erythema, lip and tongue reddening and lingual papillae hypertrophy with subsequent development of strawberry tongue ? can occur both i…

Malattia di Kawasaki tipica resistente a immunoglobuline e steroidi: uso di Infliximab.

2009

Molecular mimicry may explain multi-organ damage in COVID-19

2020

International audience

MALATTIA DI KAWASAKI ATIPICA

2019

A.L. 9 anni ricoverato presso altro PO per febbre da 4 giorni, cefalea, artralgie diffuse, vomito, diarrea ed iperemia congiuntivale bilaterale. Per rigidità nucale esegue puntura lombare (negativa) ed inizia terapia con Ceftriaxone e teicoplanina.In 6° giornata di febbre comparsa di rash (tronco e arti superiori) e dolore addominale con quota fluida nello scavo pelvico all’ETG addome. Viene trasferito presso la nostra UO per competenze. All’ingresso: febbre da 8 giorni, edemi agli arti inferiori, epatosplenomegalia e riduzione del MV alle basi, alvo chiuso a feci, non ai gas. Esami radiologici: versamento addominale periepatico, fra le anse intestinali e nello scavo pelvico e colecistite, …

MALATTIA DI KAWASAKI ED INFEZIONE DA EBV IN PAZIENTE CON TRIPLICE MUTAZIONE DEL GENE DELLA FEBBRE MEDITERRANEA FAMILIARE

2012

MALATTIA DI KAWASAKI E MAS INDOTTA DA INFEZIONE DA EBV IN PAZIENTE CON LINFOISTIOCITOSI EMOFAGOCITICA DI TIPO 2

2019

L’HLH, rara patologia da alterata risposta infiammatoria sistemica, presenta elevata mortalità, se non diagnosticata e trattata tempestivamente. Il quadro clinico è caratterizzato da febbre elevata persistente, epatosplenomegalia, citopenia di almeno due linee cellulari, linfoadenopatia generalizzata, rash, iperferritinemia, ipertrigliceridemia, ipofibrinogenemia, ipertransaminasemia e alterazioni della coagulazione. La HLH è divisa in primaria o familiare (autosomica recessiva) e secondaria (S. Autoinfiammatorie, infezioni, trapianti, ecc). La terapia si basa su chemioterapia (protocollo HLH94 e HLH2004) e, per le HLH familiari, e trapianto di midollo osseo. Fra le forme familiari, il tipo…

THE USE OF INTERLEUKIN 1 RECEPTOR ANTAGONIST (ANAKINRA) IN KAWASAKI DISEASE: A RETROSPECTIVE CASES SERIES

2018

Introduction: Persistent fever and inflammation after infusion of 2g/kg of IVIG, the standard treatment of KD represents a high-risk situation for coronary aneurysms in Kawasaki disease. Identifying patients at risk for IVIG resistance is difficult outside the Asian population, and there remains a critical unmet need to identify an anti-inflammatory treatment that is efficacious in all KD patients. Recent evidence from studies in animals and humans suggest a critical role for interleukin-1 (IL-1) α and β in the pathogenesis of KD. Objectives: To identify the clinical characteristics, reasons for use and response to treatment with anakinra in a retrospective series of patients with Kawasaki …

Kawasaki disease triggered by EBV virus in a child with Familial Mediterranean Fever

2019

Abstract Background Familial Mediterranean Fever is a monogenic autoinflammatory disease, secondary to mutation of MEFV gene, and typically expressed with recurrent attacks of fever, serositis, rash, aphthous changes in lips and/or oral mucosa. Kawasaki Disease, an acute systemic vasculitis with persistent fever (5 or more days), rash, stomatitis, conjunctivitis, lymphadenopathy, changes in extremities, is currently considered a multifactorial autoinflammatory disease. An infection, as Epstein Barr virus, can be the trigger of Kawasaki Disease. Case presentation We describe the clinical case of a 3-year-old boy with Kawasaki disease. Successfully treated with intravenous immune globulin, ac…