Search results for "Knowledge base"
showing 10 items of 142 documents
WES/WGS Reporting of Mutations from Cardiovascular "Actionable" Genes in Clinical Practice: A Key Role for UMD Knowledgebases in the Era of Big Datab…
2016
International audience; High-throughput next-generation sequencing such as whole-exome and whole-genome sequencing are being rapidly integrated into clinical practice. The use of these techniques leads to the identification of secondary variants for which decisions about the reporting or not to the patient need to be made. The American College of Medical Genetics and Genomics recently published recommendations for the reporting of these variants in clinical practice for 56 "actionable" genes. Among these, seven are involved in Marfan Syndrome And Related Disorders (MSARD) resulting from mutations of the FBN1, TGFBR1 and 2, ACTA2, SMAD3, MYH11 and MYLK genes. Here, we show that mutations col…
The representation of reality in teaching: A 'mimetic didactic' perspective on examples in plenary talk
2016
ABSTRACTUsing an observation study in Norwegian lower-secondary school classrooms this paper explores how subject matter and students’ real-world experiences are linked within the use of examples in teaching. The theory of “mimetic didactics” claims that giving students the possibility to interpret examples as both subject matter and something that is relevant to their own lives becomes a possibility through imaginative “as-if” experiences. The study finds that “as-if” experiences in the data are created by identifying with others and through a context-dependent knowledge base. The topics in the examples actualise being human within the political, economic and existential realm and offer po…
Effect of High-Fidelity Simulation on Medical Students' Knowledge about Advanced Life Support: A Randomized Study
2015
High-fidelity simulation (HFS) is a learning method which has proven effective in medical education for technical and non-technical skills. However, its effectiveness for knowledge acquisition is less validated. We performed a randomized study with the primary aim of investigating whether HFS, in association with frontal lessons, would improve knowledge about advanced life support (ALS), in comparison to frontal lessons only among medical students. The secondary aims were to evaluate the effect of HFS on knowledge acquisition of different sections of ALS and personal knowledge perception. Participants answered a pre-test questionnaire consisting of a subjective (evaluating personal percepti…
A study protocol for applying the co-creating knowledge translation framework to a population health study
2013
Background: Population health research can generate significant outcomes for communities, while Knowledge Translation (KT) aims to expressly maximize the outcomes of knowledge producing activity. Yet the two approaches are seldom explicitly combined as part of the research process. A population health study in Port Lincoln, South Australia offered the opportunity to develop and apply the co-KT Framework to the entire research process. This is a new framework to facilitate knowledge formation collaboratively between researchers and communities throughout a research to intervention implementation process. Design: This study employs a five step framework (the co-KT Framework) that is formulate…
Knowledge Acquisition in Conceptual Ontological Artificial Intelligence System
2009
The paper deals with active knowledge acquisition based on dialogue between AI system and its user. Presented method uses Conceptual Ontological Object Orientated System (COOS) to distinguish differences between concepts and to unequivocally process the input stream. In case of concepts, that do not exist in the system yet, adequate algorithms are being used to position them in ontological core. Separate concepts differ in attributes values or in sets of direct connections with other concepts. The communication aspect of the system deliver information that allow generating proper interpretation for userpsilas statement.
On incorporating the paradigms of discretization and Bayesian estimation to create a new family of pursuit learning automata
2013
Published version of an article in the journal: Applied Intelligence. Also available from the publisher at: http://dx.doi.org/10.1007/s10489-013-0424-x There are currently two fundamental paradigms that have been used to enhance the convergence speed of Learning Automata (LA). The first involves the concept of utilizing the estimates of the reward probabilities, while the second involves discretizing the probability space in which the LA operates. This paper demonstrates how both of these can be simultaneously utilized, and in particular, by using the family of Bayesian estimates that have been proven to have distinct advantages over their maximum likelihood counterparts. The success of LA-…
Ideal Chaotic Pattern Recognition is achievable: The Ideal-M-AdNN - its design and properties
2013
Published version of a chapter in the book: Transactions on Computational Collective Intelligence XI. Also available from the publisher at: http://dx.doi.org/10.1007/978-3-642-41776-4_2 This paper deals with the relatively new field of designing a Chaotic Pattern Recognition (PR) system. The benchmark of such a system is the following: First of all, one must be able to train the system with a set of “training” patterns. Subsequently, as long as there is no testing pattern, the system must be chaotic. However, if the system is, thereafter, presented with an unknown testing pattern, the behavior must ideally be as follows. If the testing pattern is not one of the trained patterns, the system …
Connectivity and Transformation in Work-Related Learning – Theoretical Foundations
2008
Remote interspecies interactions: Improving humans and animals wellbeing through mobile playful spaces
2019
[EN] Play is an essential activity for both humans and animals as it provides stimulation and favors cognitive, physical and social development. This paper proposes a novel pervasive playful environment that allows hospitalized children to participate in remote interspecies play with dogs in a dog daycare facility, while it also allows the dogs to play by themselves with the pervasive system. The aim of this playful interactive space is to help improving both children¿s and animal¿s wellbeing and their relationships by means of technologically mediated play, while creating a solid knowledge base to define the future of pervasive interactive environments for animals.
An introduction to knowledge computing
2014
This paper deals with the challenges related to self-management and evolution of massive knowledge collections. We can assume that a self-managed knowledge graph needs a kind of a hybrid of: an explicit declarative self-knowledge (as knowledge about own properties and capabilities) and an explicit procedural self-knowledge (as knowledge on how to utilize own properties and the capabilities for the self-management).We offer an extension to a traditional RDF model of describing knowledge graphs according to the Semantic Web standards so that it will also allow to a knowledge entity to autonomously perform or query from remote services different computational executions needed. We also introdu…