Search results for "L-alanine"
showing 8 items of 8 documents
Conformational properties of N-acetyl-L-alanine N',N'-dimethylamide
2004
Ab initio/DFT analysis of the conformational properties of free Ac-Ala-NMe(2) (N-acetyl-L-alanine-N',N'-dimethylamide) in terms of the N-H.O, N-H.N, C-H.O hydrogen bonds and C(delta+) = O(delta-) dipole attractions was performed. The Ala residue combined with the C-terminal tertiary amide prefers an extended conformation and that characteristic of the (i + 1)th position of the betaVIb turn. These can be easily remodelled into a structure compatible with the (i + 1)th position of the betaII/betaVIa turn. The residue has also the potential to adopt the conformation accommodated at both central positions of the betaIII/betaIII' turn or the (i + 1)th position of the betaI/beta'I turn.
CCDC 192133: Experimental Crystal Structure Determination
2003
Related Article: B.Rzeszotarska, D.Siodlak, M.A.Broda, I.Dybala, A.E.Koziol|2002|J.Pept.Res.|59|79|doi:10.1034/j.1399-3011.2002.10951.x
CCDC 740342: Experimental Crystal Structure Determination
2010
Related Article: J.Lapic, S.Djakovic, M.Cetina, K.Heinze, V.Rapic|2010|Eur.J.Inorg.Chem.||106|doi:10.1002/ejic.200900679
CCDC 192134: Experimental Crystal Structure Determination
2003
Related Article: B.Rzeszotarska, D.Siodlak, M.A.Broda, I.Dybala, A.E.Koziol|2002|J.Pept.Res.|59|79|doi:10.1034/j.1399-3011.2002.10951.x
CCDC 611082: Experimental Crystal Structure Determination
2007
Related Article: D.Siodlak, A.Macedowska-Capiga, K.Ejsmont, J.Zaleski, B.Rzeszotarska|2007|Z.Kristallogr.|222|297|doi:10.1524/zkri.2007.222.6.297
Pyrrolomycins as antimicrobial agents. Microwave-assisted organic synthesis and insights into their antimicrobial mechanism of action
2019
Abstract New compounds able to counteract staphylococcal biofilm formation are needed. In this study we investigate the mechanism of action of pyrrolomycins, whose potential as antimicrobial agents has been demonstrated. We performed a new efficient and easy method to use microwave organic synthesis suitable for obtaining pyrrolomycins in good yields and in suitable amount for their in vitro in-depth investigation. We evaluate the inhibitory activity towards Sortase A (SrtA), a transpeptidase responsible for covalent anchoring in Gram-positive peptidoglycan of many surface proteins involved in adhesion and in biofilm formation. All compounds show a good inhibitory activity toward SrtA, havi…
Experimental and theoretical studies on electropolymerization of polar amino acids on platinum electrode
2017
International audience; The anodic oxidation of polar amino acids (L-serine, L-threonine, L-asparagine, and L-glutamine) in aqueous electrolyte on smooth platinum electrode was carried out by cyclic voltammetry coupled to electrochemical quartz crystal microbalance (EQCM). pH (zwitterion, acidic and alkaline) effects on their electrochemical behavior were examined. The maximum current values are measured for zwitterion species. In addition, the current increases with increasing of concentration and scan rate, and decreases with increasing pH. The resulting passivation was studied by spectroscopic analysis such as attenuated total reflection FT infrared spectroscopy (ATR-FTIR), X-ray photoel…
Molybdenum(VI) complexes with a chiral L-alanine bisphenol [O,N,O,O’] ligand : Synthesis, structure, spectroscopic properties and catalytic activity
2023
Dioxidomolybdenum(VI) compound [MoO2Cl2(dmso)2] reacts with a chiral tetradentate O3N-type L-alanine bisphenol ligand precursor (Et3NH)H2Lala to form an oxidochloridomolybdenum(VI) complex [MoOCl(Lala)] (1) as two separable geometric isomers with phenolate groups in cis or trans positions. The single crystal X-ray and NMR analyses of cis- and trans-1 reveal that the complexes are formed of monomeric molecules, in which the ligand has a tetradentate coordination through three oxygen donors and one nitrogen donor. The reaction of Na2MoO4·2H2O with the same ligand precursor in an acidic methanol solution leads to the formation of an anionic dioxido complex (Et3NH)[MoO2(Lala)] (2) with a trans …