Search results for "L3"
showing 10 items of 80 documents
DNASE1L3 deficiency, new phenotypes, and evidence for a transient type I IFN signaling.
2022
Background: Deoxyribonuclease 1 like 3 (DNASE1L3) is a secreted enzyme that has been shown to digest the extracellular chromatin derived from apoptotic bodies, and DNASE1L3 pathogenic variants have been associated with a lupus phenotype. It is unclear whether interferon signaling is sustained in DNASE1L3 deficiency in humans. Objectives: To explore interferon signaling in DNASE1L3 deficient patients. To depict the characteristic features of DNASE1L3 deficiencies in human. Methods: We identified, characterized, and analyzed five new patients carrying biallelic DNASE1L3 variations. Whole or targeted exome and/or Sanger sequencing was performed to detect pathogenic variations in five juvenile …
Restoring Harmony in the Lifeworld? : Identity, Learning, and Leaving Preelite Sport
2020
Sport provides many youth participants with a central life project, and yet very few eventually fulfill their athletic dreams, which may lead them to disengage from sport entirely. Many studies have explored the processes of athletic retirement, but little is known about how youth athletes actually reconstruct their relationship with sport and embodiment postretirement. The authors explored these issues in the story of “Pilvi,” a Finnish alpine skier who disengaged from sport in her late adolescence. Employing an existential-phenomenological approach, they conducted six low-structured interviews with Pilvi, combined with visual methods, and identified key themes relating to the body, space,…
Spectroscopic and structural characterization of pure and FeCl3-containing tri-n-butyl phosphate
2014
The spectroscopic properties and liquid structure of pure tri-n-butyl phosphate (TBP) and FeCl3/TBP solutions have been investigated by Uv–Vis and Raman spectroscopies, X-ray diffraction and conductometry. Uv–Vis and Raman spectra, supported by conductometric measurements, consistently indicate that the solubilized salt is present mostly as TBP n [FeCl3 − n ] n+ and FeCl4 − complex ions due to specific interaction with the TBP phosphate group. Thanks to this interaction, a high amount of salt (up to 13 % w/w) can be dissolved despite the relatively low dielectric constant of TBP. The X-ray diffractogram of pure TBP has been interpreted in terms of three main contributions which can be attri…
The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser
2020
Please check the README file for more information about the dataset.
Synthesis and characterization of ethylene-1-hexene copolymers prepared by using MgCl2(THF)2-supported Ziegler-Natta catalysts
2000
Ethylene was copolymerized with 1-hexene over vanadium (VOCl3 and VCl4) and titanium (TiCl4) catalysts supported on MgCl2(THF)2 and activated with Et2AlCl. So far these catalyst systems have not been known as initiators of ethylene-1-hexene copolymerization. The vanadium catalysts were more active than the titanium catalyst and, at identical comonomer concentrations in the feed, gave rise to a greater incorporation of 1-hexene into the copolymer. Even at relatively low fractions of 1-hexene, the MgCl2(THF)2-supported catalysts affected much the copolymer properties like density, melting point and crystallinity.
Beyond life-skills: talented athletes, existential learning and (Un)learning the life of an athlete
2022
Following developments in educational discourse more broadly, learning discourses in youth sport have been shaped by outcome-based and instrumental goals of developing useful life-skills for ‘successful’ lives. There is, however, a need to expand such traditional understandings of sport-based youth development, which we undertook by exploring existential learning in sport through encountering discontinuity. We conducted in-depth qualitative research with 16 Finnish athletes (seven men/nine women, aged 19–20), five of whom had recently disengaged from the athlete development pathway. In the interviews, we used creative non-fiction vignettes to invite reflections on learning experiences in sp…
La economía social como enfoque metodológico, como objeto de estudio y como disciplina científica
1999
This article continues an article written by the same author and published by CIRIEC-España in 1997 (no. 25). It analyses social economy at three cognitive levels: first, as a social reality (Social Economy); second, as a scientific discipline which studies its previous reality (the science of Social Economy); third, as a methodological approach in social sciences (the approach of Social Economy). The author claims that, at these three levels, social economy becomes an alternative way of “making the economy”.
Cooperación condicional y tercer sector
2000
The following paper analyzes the problem of social cooperation in the provision of a public good from an evolutionary perspective. To this end we depart from behavioral programs as the basic building block for modeling individuals in the social interaction, which is based on a generalized prisoners dilemma. In it, a population of individuals follow a conditional cooperative program, which some authors refer as to morality, and that we will show that is equivalent to the application of the principle of reciprocity. It will be shown that the degree of cooperation, that is the individual contribution toward the provision of the public good, is positive although sub-optimal. Finally, if we comp…
Le point sur... Les privatisations
2005
(VF)L'objectif de ce « Point sur… » est de présenter les principales tendances actuelles guidant les recherches concernant le phénomène des privatisations. Suivant le mouvement observé en pratique depuis la fin des années quatre-vingt dix, les recherches se focalisent sur les privatisations des pays émergents et (ou) sortant d'une économie planifiée et centralisée. Les privatisations menées actuellement dans les pays de l'OCDE concernent des entreprises agissant sur des secteurs réglementés, souvent en position de monopole, et suscitent une littérature plutôt axée sur les problèmes de recherche d'une réglementation optimale que nous n'aborderons pas ici.(VA)The objective of this "Point sur.…
Privatisation, gouvernement d'entreprise et processus décisionnel:une interprétation de la dynamique organisationnelle à travers le cas France Télécom
2001
This article tries to explain the influence of privatization on the decision making process, especially in terms of investments through the corporate governance theory. In this perspective we suggest a conceptual framework based on the analysis of disciplinary mechanisms and their dynamic as a foundation of an explanatory research applied to the France Télécom case.