Search results for "L6."

Seasonal Human Coronavirus Respiratory Tract Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

2021

Abstract Background Little is known about characteristics of seasonal human coronaviruses (HCoVs) (NL63, 229E, OC43, and HKU1) after allogeneic stem cell transplantation (allo-HSCT). Methods This was a collaborative Spanish and European bone marrow transplantation retrospective multicenter study, which included allo-HSCT recipients (adults and children) with upper respiratory tract disease (URTD) and/or lower respiratory tract disease (LRTD) caused by seasonal HCoV diagnosed through multiplex polymerase chain reaction assays from January 2012 to January 2019. Results We included 402 allo-HSCT recipients who developed 449 HCoV URTD/LRTD episodes. Median age of recipients was 46 years (range,…

Stochastic Galerkin method for cloud simulation

2018

AbstractWe develop a stochastic Galerkin method for a coupled Navier-Stokes-cloud system that models dynamics of warm clouds. Our goal is to explicitly describe the evolution of uncertainties that arise due to unknown input data, such as model parameters and initial or boundary conditions. The developed stochastic Galerkin method combines the space-time approximation obtained by a suitable finite volume method with a spectral-type approximation based on the generalized polynomial chaos expansion in the stochastic space. The resulting numerical scheme yields a second-order accurate approximation in both space and time and exponential convergence in the stochastic space. Our numerical results…

Acute Myocardial Infarction and Proinflammatory Gene Variants

2007

We identified four genetic risk sets for acute myocardial infarction (AMI) from information on functional gene variants that favor inflammation or modulate cholesterol metabolism: IL6 -174 G/C, TNF -308 G/A, IL10 -1082 G/A, SERPINA3 -51 G/T, IFNG +874 T/A, HMGCR -911 C/A, and APOE ε2/3/4; 316 patients and 461 healthy subjects, all Italian. Putative risk alleles are shown underlined. The sets were identified using grade-of-membership analysis. Membership scores in the sets are automatically generated for individuals. The ''low intrinsic risk'' set had alleles that downregulate inflammation and cholesterol synthesis (IL6, TNF, ILl0, HMGCR). ''AMI across a broad age range'' carried multiple pr…

- SHADOW PRICES AND DISTANCE FUNCTIONS: AN ANALYSIS FOR FIRMS OF THE SPANISH CERAMIC PAVEMENTS INDUSTRY.

1999

This paper deals with the calculation of shadow prices for two industrial wastes generated on their production processes by a sample of eighteen firms belonging to the Spanish ceramic pavements industry. These prices are used to construct a corrected index of productivity which allows for considering wastes going with the production of marketable goods. It is followed the ethodologicalapproach first proposed by Färe, Grosskopf, Lovell y Yaisawarng (1993), which establishes a duality between distance and revenue functions. The shadow prices obtained for watery muds and used oils allow to measure in terms of a loss of marketable output the cost of achieving a marginal reduction in the product…

Factores de localización regional en las inversiones industriales

2008

En este trabajo se analiza la localización regional de la inversión industrial en España en el periodo 1964-2000, evaluando tanto la influencia de factores clásicos de demanda y coste como economías de aglomeración, y el papel desempeñado por las infraestructuras de transporte además del capital humano. Los resultados muestran que son el capital humano y las diferencias salariales los factores que más han contribuido a modificar la localización y el desplazamiento de la inversión hacia nuevos núcleos industriales, mientras que las infraestructuras de transporte y el crecimiento de los salarios han contribuido también a intensificar la utilización de capital sobre todo en las regiones con ma…

Inorganic Polyphosphate in Human Osteoblast-like Cells

1998

Significant amounts of inorganic polyphosphates and of polyphosphate-degrading exopolyphosphatase activity were detected in human mandibular-derived osteoblast-like cells. The amount of both soluble and insoluble long-chain polyphosphate in unstimulated osteoblast-like cells was higher than in human gingival cells, erythrocytes, peripheral blood mononuclear cells, and human blood plasma. The cellular content of polyphosphate in osteoblast-like cells strongly decreased after a combined treatment of the cells with the stimulators of osteoblast proliferation and differentiation, dexamethasone, beta-glycerophosphate, epidermal growth factor, and ascorbic acid. The amount of soluble long-chain p…

Synthesis and antiproliferative activity of triazenoindazoles and triazenopyrazoles: a comparative study.

2003

Several triazenoindazoles and triazenopyrazoles were prepared transforming the appropriate aminoindazoles and aminopyrazoles in the corresponding diazonium salts which were reacted with dimethylamine, diethylamine and pyrrolidine. All the triazenes were tested for their antiproliferative activity against K562, HL60, L1210 and MCF7 cell lines. The biological data showed that the benzocondensation plays a positive role on the antiproliferative activity. The (1)H-NMR spectra showed that the rotational barrier around the N(2)-N(3) bond in the triazene group can be influenced both by the position of this group in the indazole nucleus and by the substitution pattern in the benzene moiety.

QUALITY AND PRICES OF INTRA-EUROPEAN TRADE OF FOOD-INDUSTRY PRODUCTS

2000

The completion of the European Single Market should bring out an exploitation of comparative advantages in production and trade. It is usually assumed that, given the predominance of intraeuropean trade flows in the global import figures of the European Union, efficiency gains from trade creation could be potentially important. However, the analysis of the effects of the Single Market on trade specialisation with a greater degree of accuracy requires trade quality indicators to be available. This paper uses the theory of index numbers to establish the relative quality levels of the food industry shipments to the European Internal Market from European Union member countries. It is found a po…

Down-regulation of wild-type β-catenin expression by interleukin 6 in human hepatocarcinoma HepG2 and leukemia HL60 cells: a possible role in the gro…

2000

A computational approximation for the solution of retarded functional differential equations and their applications to science and engineering

2021

<p style='text-indent:20px;'>Delay differential equations are of great importance in science, engineering, medicine and biological models. These type of models include time delay phenomena which is helpful for characterising the real-world applications in machine learning, mechanics, economics, electrodynamics and so on. Besides, special classes of functional differential equations have been investigated in many researches. In this study, a numerical investigation of retarded type of these models together with initial conditions are introduced. The technique is based on a polynomial approach along with collocation points which maintains an approximated solutions to the problem. Beside…