Search results for "L8."
showing 10 items of 37 documents
Motivations, engagement and adoption of e-WOM in restaurants.
2022
Resumen El objetivo del presente trabajo fue estudiar el efecto que tienen las motivaciones para consultar y escribir e-WOM sobre el compromiso con el e-WOM y la influencia de dicho compromiso en la adopción del e-WOM consultado. Para analizar estas relaciones, se realizó una investigación empírica aplicada en el contexto de los restaurantes. El ámbito geográfico fue Ecuador, con una muestra de 461 consumidores. Se utilizó un modelo de ecuaciones estructurales y se validó la cadena de relaciones. Los resultados confirmaron las relaciones entre estas variables; además, se presentaron implicaciones académicas interesantes para profundizar en el estudio sobre el compromiso con el e-WOM, así co…
Associations of epstein-barr virus-positive gastric adenocarcinoma with circulating mediators of inflammation and immune response
2018
Epstein-Barr virus (EBV)-positive gastric adenocarcinoma exhibits locally intense inflammation but systemic manifestations are uncertain. Our study examined whether circulating mediators of inflammation and immune response differ by tumor EBV status. From a Latvian series of 302 gastric cancer cases, we measured plasma levels of 92 immune-related proteins in the 28 patients with EBV-positive tumors and 34 patients with EBV-negative tumors. Eight markers were statistically significantly higher with tumor EBV positivity: chemokine C-C motif ligand (CCL) 20 (Odds Ratio (OR) = 3.6; p-trend = 0.001), chemokine C-X-C motif ligand 9 (OR = 3.6; p-trend = 0.003), programmed death-ligand 1 (PD-L1; OR…
Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs.
2021
Mitochondria contain a specific translation machinery for the synthesis of mitochondria-encoded respiratory chain components. Mitochondrial tRNAs (mt-tRNAs) are also generated from the mitochondrial DNA and, similar to their cytoplasmic counterparts, are post-transcriptionally modified. Here, we find that the RNA methyltransferase METTL8 is a mitochondrial protein that facilitates 3-methyl-cytidine (m3C) methylation at position C32 of the mt-tRNASer(UCN) and mt-tRNAThr. METTL8 knockout cells show a reduction in respiratory chain activity, whereas overexpression increases activity. In pancreatic cancer, METTL8 levels are high, which correlates with lower patient survival and an enhanced resp…
The One Savior Paradigm
2009
The one savior paradigm is discussed not only as doctrinal aspect of religious teachings but as one of mostly manifested aspect of our psychic, that should be adequately investigated. We suggest simple idea that could serve as starting cognitive model for the one savior paradigm, that might give effect in considering global aspects of humanity, e.g., such as global economy and exact sciences in more friendly connection with religious thinking.
Can we be satisfied with our football team? Evidence from spanish professional football.
2009
This article assesses the sporting performance of Spanish professional football teams at competition level, namely, League, King’s Cup, and European competitions (Champions League and Union of European Football Associations [UEFA] Cup). Then, the gap between the result obtained by a team at the end of a season and that expected according to its potential is used as a proxy of the degree of satisfaction that fans should feel: the narrower the gap the greater the level of satisfaction. Regarding methodology, Data Envelopment Analysis techniques and directional distance functions are used. Results reveal that most teams perform rather differently across competitions, the lower average performa…
A general equilibrium analysis of climate change impacts on tourism
2006
This paper studies the economic implications of climate-change-induced variations in tourism demand, using a world CGE model. The model is first re-calibrated at some future years, obtaining hypothetical benchmark equilibria, which are subsequently perturbed by shocks, simulating the effects of climate change. We portray the impact of climate change on tourism by means of two sets of shocks, occurring simultaneously. The first set of shocks translate predicted variations in tourist flows into changes of consumption preferences for domestically produced goods. The second set reallocate income across world regions, simulating the effect of higher or lower tourists' expenditure. Our analysis h…
Sustainable tourist development in Italian holiday destinations
2008
This paper argues that tourism, will become a major activity in a modern welfare state, which will have serious consequences for environmental sustainability. This issue calls for an assessment of the pros and cons of the ecological efficiency of tourism. We propose an overall efficiency indicator that comprises both a sustainable tourism index and an economic efficiency index. Based on a data set for Italian provinces and using Activity Analysis, a quantitative assessment of the relative position of Italian tourist destination areas is made from the perspective of sustainable tourism. Copyright © 2008 Inderscience Enterprises Ltd.
La producción científica sobre distribución comercial en España, 1990-2000
2002
Este trabajo presenta una revisión bibliográfica de la investigación académica sobre distribución comercial publicada en España en el horizonte temporal de 1990 a 2000. Tras una revisión de los trabajos sobre el estado de la cuestión de la investigación en marketing, y las aportaciones más específicas en el campo de la distribución comercial, presentamos la metodología y los principales resultados de la revisión de un número de trabajos procedentes de las publicaciones más relevantes en el campo del marketing. Se extraen conclusiones sobre el carácter científico de los trabajos, los grupos de investigación, la metodología empleada y el contenido de los trabajos y, finalmente, se proponen lí…
Fundamental isomorphism theorems for quantum groups
2017
The lattice of subgroups of a group is the subject of numerous results revolving around the central theme of decomposing the group into "chunks" (subquotients) that can then be compared to one another in various ways. Examples of results in this class would be the Noether isomorphism theorems, Zassenhaus' butterfly lemma, the Schreier refinement theorem for subnormal series of subgroups, the Dedekind modularity law, and last but not least the Jordan-H\"older theorem. We discuss analogues of the above-mentioned results in the context of locally compact quantum groups and linearly reductive quantum groups. The nature of the two cases is different: the former is operator algebraic and the latt…
Familial combined hypolipidemia due to mutations in the ANGPTL3 gene
2013
The role of ANGPTL3 in lipoprotein metabolism emerged from studies in a mutant mouse strain characterized by severe hypotriglyceridemia and carrying a loss-of-function (LOF) mutation of the ANGPTL3 gene. ANGPTL3 was found to inhibit lipoprotein lipase and endothelial lipase. Genome-wide association studies in humans demonstrated the association of ANGPTL3 variants with plasma triglyceride levels and LOF mutations of ANGPTL3 were found in hypotriglyceridemic subjects in population studies. Recently, individuals originally classified as affected by familial hypobetalipoproteinemia were found to be homozygotes/compound heterozygotes for rare LOF mutations of ANGPTL3. They show a striking reduc…