Search results for "L8."

DYNAMIC SEMANTIC USER PROFILING FROM IMPLICIT WEB NAVIGATION DATA

2014

International audience; On the Web, pages are often dynamically generated and allow publishers to individually adapt contents to each viewer. Underlying systems must correctly understand the user's context - crucial especially in the case of online advertisement placement. The article at hand describes our proposition of a novel profiling system, adapted to the special needs of digital advertising. Based on Semantic Web Technologies, the MindMinings system relies on an ontology to enable thorough understanding of each user's context and needs. The underlying ontology structure also provides enhanced interoperability with semantically annotated knowledge resources, notably vocabularies from …

Cannabinoid 1 Receptors in Keratinocytes Modulate Proinflammatory Chemokine Secretion and Attenuate Contact Allergic Inflammation

2013

Abstract Epidermal keratinocytes (KCs) and cannabinoid (CB) receptors both participate in the regulation of inflammatory responses in a mouse model for allergic contact dermatitis, the contact hypersensitivity (CHS) response to the obligate sensitizer 2,4-dinitrofluorobenzene. In this study, we investigated the cellular and molecular mechanisms how CB1 receptors attenuate CHS responses to 2,4-dinitrofluorobenzene. We used a conditional gene-targeting approach to identify the relative contribution of CB1 receptors on epidermal KCs for the control of CHS responses. To determine the underlying cellular and molecular mechanisms that regulate inflammatory responses in the effector phase of CHS, …

Sectoral Transformations in Neo-Patrimonial Rentier States: Tourism Development and State Policy in Egypt

2007

This article challenges claims that liberalising state regulated markets in developing countries may induce lasting economic development. The analysis of the rise of tourism in Egypt during the last three decades suggests that the effects of liberalisation and structural adjustment are constrained by the neo-patrimonial character of the Egyptian political system. Since the decline of oil rent revenues during the 1980s tourism development was the optimal strategy to compensate for the resulting fiscal losses. Increasing tourism revenues have helped in coping with macroeconomic imbalances and in avoiding more costly adjustment of traditional economic sectors. Additionally, they provided the p…

RNA recognition by human TLR8 can lead to autoimmune inflammation

2013

High expression level of human TLR8 in mice results in spontaneous, multiorgan inflammation attributable in part to increased DC activation.

Marketing de l'Art et de la Culture

2009

2e édition; International audience; Les organisations culturelles modernes ont besoin d'une démarche et d'outils marketing rigoureux adaptés à leurs spécificités. Cet ouvrage de référence poursuit un double objectif : éclairer le lecteur sur les caractéristiques du secteur et définir les enjeux stratégiques et outils opérationnels du marketing dans les principaux domaines des arts et de la culture (spectacle vivant, patrimoine, industries culturelles). Dans le secteur des arts et de la culture le marketing souffre d'un fort déficit d'image. Pourtant qu'il s'agisse de lancer des projets, de nouer des relations avec des partenaires, d'attirer et de fidéliser des publics, de démocratiser l'acc…

Un enfoque de marketing de relaciones a la educación como un servicio: aplicación a la Universidad de Valencia

2014

Esta investigación se plantea como una aproximación exploratoria a la vez que innovadora, en la medida en que su objetivo básico es el de aplicar el paradigma del marketing de relaciones al análisis de la gestión educativa. Más concretamente, lo que se persigue es construir un modelo integrado de relaciones entre el egresado y la universidad. Se realizaron 500 encuestas a egresados de una universidad española y se utilizaron modelos de ecuaciones estructurales para contrastar las relaciones planteadas. La aportación fundamental del trabajo radica en la conceptuación y medición de variables relativas al comportamiento y percepción de los egresados. Los resultados más relevantes confirman tre…

Como as práticas ecológicas e o desperdício de alimentos influenciam o capital de marca do restaurante?

2020

Resumen El presente trabajo tuvo por objetivo evaluar la incidencia de las prácticas verdes, la innovación sostenible y el manejo del desperdicio alimentario en la construcción del capital de marca de los restaurantes. A partir de una investigación cuantitativa dirigida a responsables de restaurantes en Ecuador, se obtuvieron 120 cuestionarios válidos que permitieron estimar un modelo de ecuaciones estructurales a través de la regresión de mínimos cuadrados parciales. Los resultados obtenidos evidencian que las prácticas verdes orientadas a la formación del empleado y la innovación sostenible contribuyen significativamente a la reducción del desperdicio alimentario, que, a su vez, junto a l…

Role of interleukin 8 in exosome-mediated crosstalk between chronic myelogenous leukaemia cells and bone marrow stromal cells

2013

Crosstalk between chronic myelogenous leukemia (CML) and bone marrow stromal cells: role of interleukin 8 and CML derived- exosomes

2013

Chronic myelogenous leukemia (CML) is a myeloproliferative disorder characterized by the t(9:22) (q34:q11) reciprocal translocation, resulting in the expression of the chimeric Bcr–Abl oncoprotein with constitutive tyrosine kinase activity. Exosomes (Exo) are small vesicles of endosomal origin and of 40-100 nm diameter released by many cell types including cancer cells. Several data indicate that Exo play an important role in cell-to-cell communication and tumor-stroma interaction, thus potentially affecting cancer progression. It is well known that stromal microenvironment contributes to disease progression through the establishment of a bi-directional crosstalk with cancer cells. In the b…

Attractiveness and Effectiveness of Competing Tourist Areas: A Study on Italian Provinces

2005

Tourism has become a wide-spread phenomenon in our age and a focal point of economic policy of many regions competing for the favours of tourists. Consequently, competitiveness of tourist destinations has received increasing interest in economic research with a view to the identification of the user attractiveness of a tourist area. The present paper is inspired by the conceptual competitiveness model developed by Crouch and Ritchie and presents an attempt to assess the relative attractiveness of tourist destinations on the basis of aggregate tourist strength of competing destinations. The main novelty of the present work is formed by the micro-based foundation of tourism attractiveness of …